tag:blogger.com,1999:blog-15174486913853617542024-03-14T09:59:36.882-07:00Scientific Health JournalThe Scientific Health Journal is a resource and publication providing facts and findings from advanced scientific health research that is now available for health care providers and families.Unknownnoreply@blogger.comBlogger30125tag:blogger.com,1999:blog-1517448691385361754.post-6308266856044200082015-05-11T09:21:00.002-07:002015-05-11T09:21:43.805-07:00The Spread of DNA - Further Research NeededThis is a very curious area of study but one that warrants a more in depth review.<br />
<br />
<br />
DID YOU KNOW? Women (or men) absorb and carry living DNA and cells from every male they ever have had sexual intercouse with. In fact anyone who has assumed male spermatozoa into their bodily system has the living cells and genetic energetic imprint/signature of each individual whose sperm they have consumed or received IN ANY WAY. <br />
<br />
Don't have sex with anyone who you wouldn't want to be- This adv<span class="text_exposed_hide">...</span><span class="text_exposed_show">ice, if followed, would transform the energy on Earth from war, hatred and strife to that of love, peace and concord.<br /> <br /> This phenomena is called "Male Microchimerism"<br /> Microchimerism is the harboring of small numbers of cells that originated in a genetically different individual.<br /> <br /> "BUT, when they autopsied the brains of women who had never even been pregnant they STILL found male DNA prevalent in the female brain. <br /> <br /> They did their best to hide the evidence. They buried it in numerous sub studies but I sifted through it all and found the damning statement, the one they tried to avoid. The statement that every single article written about this extremely important study completely censored and left out. <br /> <br /> What are they so afraid of??<br /> <br /> "CONCLUSIONS: Male microchimerism was not infrequent in women without sons. Besides known pregnancies, other possible sources of male microchimerism include unrecognized spontaneous abortion, vanished male twin, an older brother transferred by the maternal circulation, or SEXUAL INTERCOURSE. Male microchimerism was significantly more frequent and levels were higher in women with induced abortion than in women with other pregnancy histories. Further studies are needed to determine specific origins of male microchimerism in women."<br /> <br /> Its so convenient how they flat out ignore the MOST OBVIOUS source of microchimerism male DNA hosting inside the female body. And the periodicals just deleted it alltogether. The scum bags. <br /> <br /> This has very important ramifications for women. Especially promiscuous women who practice unprotected sexual intercourse. Every male you absorb spermatazoa from becomes a living part of you FOR LIFE. The women autopsied in this study were elderly. Some had carried the living male DNA for well over 50 years! <br /> <br /> This will certainly piss the feminists off. But it explains so much about women, life, and relationships. <br /> <br /> Sperm is alive. It is living cells. When it is injected into you it swims and attaches and burrows into your flesh. If its in your mouth it swims and climbs into your nasal passages, inner ear, and behind your eyes. Then digs in. It enters your blood stream and collects in your brain and spine. Like something out of a scifi movie. <br /> <br /> I love how the agenda has convinced young ladies to be promiscuous. They knowingly are sabotaging generations of young women. Of COURSE they are. <br /> <br /> The male DNA can also pass into and become part of a fetus from an entirely different male. So if your woman has a long track record, then your kids are likely carrying DNA from her past hookups. <br /> <br /> Is this why the ancient Sumerian Gods specifically said to not have premarital sex? Is this why they forbid homosexuality?<br /> <br /> We have only begun to understand the power and ramifications of this. <br /> Links below:<br /> <br /> Male microchimerism in women without sons: quantitative assessment and correlation with pregnancy history<br /> <a href="http://l.facebook.com/l.php?u=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fm%2Fpubmed%2F16084184%2F&h=sAQHQ7HX1&enc=AZOSFleB5kt_da6VioSnVCegV5ckJr7KPxNlYayWdUkjPoav-QGzpqh8Hbt-MswzdPddDYab0R91qWdyGoOYdlVeHqPHFFa8QD898nDDRlrKj8qYPa1lE6XSNQcc-wdgInEWg6vzKXmUAPl18YrA_hNB9hs0OROC1Nd1l3gG8K1zK0bOR-Na7nWDiTOFhlp9tcY&s=1" onclick="LinkshimAsyncLink.swap(this, "http:\/\/l.facebook.com\/l.php?u=http\u00253A\u00252F\u00252Fwww.ncbi.nlm.nih.gov\u00252Fm\u00252Fpubmed\u00252F16084184\u00252F&h=sAQHQ7HX1&enc=AZOSFleB5kt_da6VioSnVCegV5ckJr7KPxNlYayWdUkjPoav-QGzpqh8Hbt-MswzdPddDYab0R91qWdyGoOYdlVeHqPHFFa8QD898nDDRlrKj8qYPa1lE6XSNQcc-wdgInEWg6vzKXmUAPl18YrA_hNB9hs0OROC1Nd1l3gG8K1zK0bOR-Na7nWDiTOFhlp9tcY&s=1");" onmouseover="LinkshimAsyncLink.swap(this, "http:\/\/www.ncbi.nlm.nih.gov\/m\/pubmed\/16084184\/");" rel="nofollow nofollow" target="_blank">http://<wbr></wbr><span class="word_break"></span>www.ncbi.nlm.nih.gov/m/<wbr></wbr><span class="word_break"></span>pubmed/16084184/</a><br /> <br /> Women absorb and carry living DNA and cells from every male they have sexual intercouse with<br /> <a href="http://www.godlikeproductions.com/forum1/message2299543/pg1" onclick="LinkshimAsyncLink.swap(this, "http:\/\/l.facebook.com\/l.php?u=http\u00253A\u00252F\u00252Fwww.godlikeproductions.com\u00252Fforum1\u00252Fmessage2299543\u00252Fpg1&h=vAQGpiHP4&enc=AZNyUd7Yb6KAaw_0nxTriKFuyoHq32fIfi2ArCBz9ZCMSmSUyaRKOODEreILFHEPwMn7o94uYYCgIXNGOdmbFLejSSZHz-E3kXAhau8CZzVXlMhOUBKBQMBhS1ENiAa_Np5nzVHqYHBXwcCYV8AVczAWkbZumVIv-i-6AhS6KF09SGh2mbTsKrd3JR1jaPrYx5w&s=1");" onmouseover="LinkshimAsyncLink.swap(this, "http:\/\/www.godlikeproductions.com\/forum1\/message2299543\/pg1");" rel="nofollow nofollow" target="_blank">http://<wbr></wbr><span class="word_break"></span>www.godlikeproductions.com/<wbr></wbr><span class="word_break"></span>forum1/message2299543/pg1</a><br /> <br /> Male Microchimerism in the Human Female Brain<br /> " In conclusion, male microchimerism is frequent and widely distributed in the human female brain."<br /> <a href="http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0045592#pone.0045592-Lambert1" onclick="LinkshimAsyncLink.swap(this, "http:\/\/l.facebook.com\/l.php?u=http\u00253A\u00252F\u00252Fjournals.plos.org\u00252Fplosone\u00252Farticle\u00253Fid\u00253D10.1371\u0025252Fjournal.pone.0045592\u002523pone.0045592-Lambert1&h=DAQHUWAQE&enc=AZMRjGxRRkSerGzb-kPSFHUGGeAoWJPHJW4PAAl-lOwuGhNC2AV1omeveIjKE9x95gOtBceABal6k7zSaMxnU9erWxeoDk-eQI7zRfkXGmWalYmukKlAIdHTw2TXPrTmDO96hA75-Lpbvrpbbk6Ebs1gUgTWFjbJqNZIJocaF6p_-bDoFIEUl4XgrylX10lI7zg&s=1");" onmouseover="LinkshimAsyncLink.swap(this, "http:\/\/journals.plos.org\/plosone\/article?id=10.1371\u00252Fjournal.pone.0045592#pone.0045592-Lambert1");" rel="nofollow nofollow" target="_blank">http://journals.plos.org/<wbr></wbr><span class="word_break"></span>plosone/<wbr></wbr><span class="word_break"></span>article?id=10.1371%2Fjourna<wbr></wbr><span class="word_break"></span>l.pone.0045592#pone.004559<wbr></wbr><span class="word_break"></span>2-Lambert1</a></span><span class="text_exposed_hide"> <span class="text_exposed_link"><a class="see_more_link" data-ft="{"tn":"e"}" href="https://www.blogger.com/blogger.g?blogID=1517448691385361754#" onclick="var func = function(e) { e.preventDefault(); }; var parent = Parent.byClass(this, "text_exposed_root"); if (parent && parent.getAttribute("id") == "id_5550d68f592ff6404008504") { CSS.addClass(parent, "text_exposed"); Arbiter.inform("reflow"); }; func(event); " role="button">See More</a></span></span><span class="fbPhotoTagList" id="fbPhotoSnowliftTagList"><span class="fcg"> — with <span class="fbPhotoTagListTag tagItem"><input autocomplete="off" name="tag[]" type="hidden" value="100004185820038" /><a class="taggee" data-hovercard="/ajax/hovercard/hovercard.php?id=100004185820038&type=mediatag&media_info=6.10152837975942011" data-tag="100004185820038" href="https://www.facebook.com/alan.dawson.7315">Alan Dawson</a></span>.</span></span><br />
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Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-63493882147604735772013-07-15T18:50:00.000-07:002013-07-15T18:50:03.418-07:00CHEMOTHERAPY<span style="font-size: large;">In the video below Dr. Peter Glidden cites the study that concludes better than 97% of the time, chemotherapy does not work. Yet it’s one of the main treatments in the battle against cancer. Dr. Glidden explains why that’s still the case.</span><br />
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<center>
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<param name="allowFullScreen" value="true"></param>
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<br />
<span style="font-size: large;">Dr. Peter Glidden talks about the incredibly low success rate for chemotherapy as a cancer treatment. Be sure to talk to your doctor about all of your options before deciding on a cancer treatment path.</span>
<br />
<br />
More on <a href="http://www.advancedhealthplan.com/page3.html" target="_blank">Understanding Cancer:</a> <br />
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<a href="http://www.advancedhealthplan.com/page3.html" target="_blank">http://www.advancedhealthplan.com/page3.html</a><br />
<br />
<a href="http://cannabiscures.blogspot.com/" target="_blank">http://cannabiscures.blogspot.com</a><br />
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Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-11829067617181123742013-07-13T10:03:00.000-07:002013-07-13T10:03:35.509-07:00ANTIBIOTICS<div class="section abstract" id="abstract-3">
<div id="p-6">
<span style="font-size: large;">Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells</span></div>
<em></em><br />
<em>Sci Transl Med<span class="slug-pub-date" itemprop="datePublished">
3 July 2013:
</span><br />
<span class="slug-vol">
Vol. 5,
</span><span class="slug-issue">
Issue 192,
</span><span class="slug-pages">
p.
192ra85
</span>
<br />
Sci. Transl. Med. DOI:
<span class="slug-doi" title="10.1126/scitranslmed.3006055">10.1126/scitranslmed.3006055
</span></em><br />
<span style="font-size: large;"></span><br />
<br />
<span style="font-size: large;">ABSTRACT: Prolonged
antibiotic treatment can lead to detrimental side effects in patients,
including ototoxicity, nephrotoxicity, and
tendinopathy, yet the mechanisms underlying the
effects of antibiotics in mammalian systems remain unclear. It has been
suggested
that bactericidal antibiotics induce the
formation of toxic reactive oxygen species (ROS) in bacteria. We show
that clinically
relevant doses of bactericidal
antibiotics—quinolones, aminoglycosides, and β-lactams—cause
mitochondrial dysfunction and
ROS overproduction in mammalian cells. We
demonstrate that these bactericidal antibiotic–induced effects lead to
oxidative
damage to DNA, proteins, and membrane lipids.
Mice treated with bactericidal antibiotics exhibited elevated oxidative
stress
markers in the blood, oxidative tissue damage,
and up-regulated expression of key genes involved in antioxidant defense
mechanisms,
which points to the potential physiological
relevance of these antibiotic effects. The deleterious effects of
bactericidal
antibiotics were alleviated in cell culture and
in mice by the administration of the antioxidant <em>N</em>-acetyl-<span class="sc">l</span>-cysteine
or prevented by preferential use of bacteriostatic antibiotics. This
work highlights the role of antibiotics in
the production of oxidative tissue damage in
mammalian cells and presents strategies to mitigate or prevent the
resulting
damage, with the goal of improving the safety of
antibiotic treatment in people.</span>
<br />
</div>
<br />
<ul class="copyright-statement">
<li class="fn" id="copyright-statement-1">Copyright © 2013, American Association for the Advancement of Science</li>
</ul>
<div class="dynamic-citation-bottom">
<div class="custom-cit">
<span class="custom-cit-label">Citation: </span><span class="custom-cit-author">S. Kalghatgi, C. S. Spina, J. C. Costello, M. Liesa, J. R. Morones-Ramirez, S. Slomovic, A. Molina, O. S. Shirihai, J. J.
Collins, </span><span class="custom-cit-title">Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells. </span><span class="custom-cit-jour-title">Sci. Transl. Med. </span><span class="custom-cit-volume">5</span><span class="custom-cit-volume-sep">, </span><span class="custom-cit-fpage">192ra85</span><span class="custom-cit-date"> (2013).</span></div>
<div class="custom-cit">
</div>
<div class="custom-cit">
SOURCE: <a href="http://stm.sciencemag.org/content/5/192/192ra85.abstract">http://stm.sciencemag.org/content/5/192/192ra85.abstract</a></div>
</div>
<ul class="copyright-statement">
</ul>
Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-46620349660647402262013-07-07T16:23:00.000-07:002013-07-07T16:23:47.358-07:00BIOPHOTONS<div class="nd-region-header clear-block ">
<div class="field field-post-date-custom post-date-custom">
<div>
<b><h1>
<span style="font-size: large;">Biophotons: The Human Body Emits, Communicates with, and is Made from Light</span></h1>
<a href="http://www.greenmedinfo.com/gmi-blogs/sayer%20ji"></a></b></div>
</div>
</div>
<div class="nd-region-middle-wrapper nd-no-sidebars">
<div class="nd-region-middle">
<div class="field field-body">
<div class="rtecenter">
<em><strong>Increasingly science agrees with the poetry of direct
human experience: we are more than the atoms and molecules that make up
our bodies, but beings of light as well. Biophotons are emitted by the
human body, can be released through mental intention, and may modulate
fundamental processes within cell-to-cell communication and DNA.</strong></em></div>
Nothing is more amazing than the highly improbable fact that <u>we exist</u>. We often ignore this fact, oblivious to the reality that instead of something there <em>could </em>be
nothing at all, i.e. why is there a universe (poignantly aware of
itself through us) and not some void completely unconscious of itself?<br />
Consider that from light, air, water, basic minerals within the crust
of the earth, and the at least 3 billion year old information contained
within the nucleus of one diploid zygote cell, the human body is
formed, and within that body a soul capable of at least trying to
comprehend its bodily and spiritual origins.<br />
Given the sheer insanity of our existential condition, and bodily
incarnation as a whole, and considering that our earthly existence is
partially formed from sunlight and requires the continual consumption of
condensed sunlight in the form of food, it may not sound so farfetched <strong>that our body emits light.</strong><br />
Indeed, the human body emits <strong><a href="http://www.greenmedinfo.com/keyword/biophotons">biophotons</a></strong>,
also known as ultraweak photon emissions (UPE), with a visibility 1,000
times lower than the sensitivity of our naked eye. While not visible to
us, these particles of light (or waves, depending on how you are
measuring them) are part of the visible electromagnetic spectrum
(380-780 nm) and are detectable via sophisticated modern
instrumentation.<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn1" name="_ftnref1" title="">[1]</a><sup>,<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn2" name="_ftnref2" title="">[2]</a></sup><br />
<h1>
<span style="font-size: large;">The Physical and "Mental" Eye Emits Light</span></h1>
The eye itself, which is continually exposed to ambient powerful
photons that pass through various ocular tissues, emit spontaneous and
visible light-induced ultraweak photon emissions.<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn3" name="_ftnref3" title="">[3]</a>
It has even been hypothesized that visible light induces delayed
bioluminescence within the exposed eye tissue, providing an explanation
for the origin of the negative afterimage.<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn4" name="_ftnref4" title="">[4]</a><br />
These light emissions have also been correlated with cerebral energy metabolism and oxidative stress within the mammalian brain.<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn5" name="_ftnref5" title="">[5]</a> <a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn6" name="_ftnref6" title="">[6]</a>
And yet, biophoton emissions are not necessarily epiphenomenal.
Bókkon's hypothesis suggests that photons released from chemical
processes within the brain produce biophysical pictures during visual
imagery, and a recent study found that when subjects actively imagined
light in a very dark environment <em>their intention</em> produced significant increases in ultraweak photo emissions.<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn7" name="_ftnref7" title="">[7]</a>
This is consistent with an emerging view that biophotons are not
solely cellular metabolic by-products, but rather, because biophoton
intensity can be considerably higher inside cells than outside, it is
possible for the mind to access this energy gradient to create intrinsic
biophysical pictures during visual perception and imagery.<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn8" name="_ftnref8" title="">[8]</a><br />
<div class="rtecenter">
<img alt="The Human Eye Emits Light" src="http://www.greenmedinfo.com/sites/default/files/ckeditor/Sayer%20Ji/images/see-eye-to-eye.jpg" /></div>
<h1>
<span style="font-size: large;">Our Cells and DNA Use Biophotons To Store and Communicate Information</span></h1>
Apparently biophotons are used by the cells of many living organisms
to communicate, which facilitates energy/information transfer that is
several orders of magnitude faster than chemical diffusion. According to
a 2010 study, "Cell to cell communication by biophotons have been
demonstrated in plants, bacteria, animal neutriophil granulocytes and
kidney cells."<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn9" name="_ftnref9" title="">[9]</a>
Researchers were able to demonstrate that "...different spectral light
stimulation (infrared, red, yellow, blue, green and white) at one end of
the spinal sensory or motor nerve roots resulted in a significant
increase in the biophotonic activity at the other end." Researchers
interpreted their finding to suggest that "...light stimulation can
generate biophotons that conduct along the neural fibers, probably as
neural communication signals."<br />
Even when we go down to the molecular level of our genome, DNA can be
identified to be a source of biophoton emissions as well. One author
proposes that DNA is so biophoton dependent that is has <a href="http://en.wikipedia.org/wiki/Excimer_laser">excimer laser-like properties</a>, enabling it to exist in a stable state far from thermal equilibrium at threshold.<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn10" name="_ftnref10" title="">[10]</a><br />
Technically speaking a biophoton is an elementary particle or quantum
of light of non-thermal origin in the visible and ultraviolet spectrum
emitted from a biological system. They are generally believed to be
produced as a result of energy metabolism within our cells, or more
formally as a "...by-product of biochemical reactions in which excited
molecules are produced from bioenergetic processes that involves active
oxygen species," <a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn11" name="_ftnref11" title="">[11]</a><br />
<h1>
<span style="font-size: large;">The Body's Circadian Biophoton Output</span></h1>
Because the metabolism of the body changes in a circadian fashion,
biophoton emissions also variate along the axis of diurnal time. <a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn12" name="_ftnref12" title="">[12]</a>
Research has mapped out distinct anatomical locations within the body
where biophoton emissions are stronger and weaker, depending on the time
of the day:<br />
<blockquote>
Generally, the fluctuation in photon counts over the body was lower
in the morning than in the afternoon. The thorax-abdomen region emitted
lowest and most constantly. The upper extremities and the head region
emitted most and increasingly over the day. Spectral analysis of low,
intermediate and high emission from the superior frontal part of the
right leg, the forehead and the palms in the sensitivity range of the
photomultiplier showed the major spontaneous emission at 470-570 nm. The
central palm area of hand emission showed a larger contribution of the
420-470 nm range in the spectrum of spontaneous emission from the hand
in autumn/winter. The spectrum of delayed luminescence from the hand
showed major emission in the same range as spontaneous emission.</blockquote>
The researchers concluded that "The spectral data suggest that
measurements might well provide quantitative data on the individual
pattern of peroxidative and anti-oxidative processes in vivo."<br />
<h1>
<span style="font-size: large;">Meditation and Herbs Affect Biophoton Output</span></h1>
Research has found an oxidative stress-mediated difference in
biophoton emission among mediators versus non-meditators. Those who
meditate regularly tend to have lower ultra-weak photon emission (UPE,
biophoton emission), which is believed to result from the lower level of
free radical reactions occurring in their bodies. In one clinical study
involving practitioners of transcendental meditation (TM) researchers
found:<br />
<blockquote>
The lowest UPE intensities were observed in two subjects who
regularly meditate. Spectral analysis of human UPE has suggested that
ultra-weak emission is probably, at least in part, a reflection of free
radical reactions in a living system. It has been documented that
various physiologic and biochemical shifts follow the long-term practice
of meditation and it is inferred that meditation may impact free
radical activity.<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn13" name="_ftnref13" title="">[13]</a></blockquote>
Interestingly, an herb well-known for its use in stress reduction
(including inducing measurable declines in cortisol), and associated
heightened oxidative stress, has been tested clinically in reducing the
level of biophotons emitted in human subjects. Known as <strong><a href="http://www.greenmedinfo.com/substance/rhodiola-tibetan-ginseng">rhodiola</a></strong>, a study published in 2009 in the journal <em>Phytotherapeutic Research</em>
found that those who took the herb for 1 week has a significant
decrease in photon emission in comparison with the placebo group.<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn14" name="_ftnref14" title="">[14]</a><br />
<h1>
<span style="font-size: large;">Human Skin May Capture Energy and Information from Sunlight</span></h1>
Perhaps most extraordinary of all is the possibility that our bodily
surface contains cells capable of efficiently trapping the energy and
information from ultraviolet radiation. A study published in the <em>Journal of Photochemistry and Photobiology </em>in
1993, titled, "Artificial sunlight irradiation induces ultraweak photon
emission in human skin fibroblasts," discovered that when light from an
artificial sunlight source was applied to fibroblasts from either
normal subjects or with the condition xeroderma pigmentosum,
characterized by deficient DNA repair mechanisms, it induced far higher
emissions of ultraweak photons (10-20 times) in the xeroderma
pigmentosum group. The researchers concluded from this experiment that
"These data suggest that xeroderma pigmentosum cells tend to lose the
capacity of efficient storage of ultraweak photons, <strong>indicating the existence of an efficient intracellular photon trapping system within human cells.</strong>"<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn15" name="_ftnref15" title="">[15]</a> More recent research has also identified measurable differences in biophoton emission between normal and melanoma cells.<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn16" name="_ftnref16" title="">[16]</a><br />
<br />
<div class="rtecenter">
In a previous article,<strong> </strong><a href="http://www.greenmedinfo.com/blog/does-skin-pigment-act-natural-solar-panel"><strong>Does Skin Pigment Act Like A Natural Solar-Pane</strong>l</a>, we explored the role of melanin in converting ultraviolet light into metabolic energy:</div>
<blockquote>
Melanin is capable of transforming ultraviolet light energy into
heat in a process known as "ultrafast internal conversion"; more than
99.9% of the absorbed UV radiation is transformed from potentially
genotoxic (DNA-damaging) ultraviolet light into harmless heat.<br />
If melanin can convert light into heat, could it not also transform
UV radiation into other biologically/metabolically useful forms of
energy? This may not seem so farfetched when one considers that even
gamma radiation, which is highly toxic to most forms of life, is a
source of sustenance for certain types of fungi and bacteria.</blockquote>
<h1>
<span style="font-size: large;">The Body's Biophoton Outputs Are Governed by Solar and Lunar Forces</span></h1>
It appears that modern science is only now coming to recognize the
ability of the human body to receive and emit energy and information
directly from the light given off from the Sun. <a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn17" name="_ftnref17" title="">[17]</a><br />
There is also a growing realization that the Sun and Moon affect
biophoton emissions through gravitational influences. Recently,
biophoton emissions from wheat seedlings in Germany and Brazil were
found to be synchronized transcontinentally according to rhythms
associated with the lunisolar tide.<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn18" name="_ftnref18" title="">[18]</a>
In fact, the lunisolar tidal force, to which the Sun contributes 30 %
and the Moon 60 % of the combined gravitational acceleration, has been
found to regulate a number of features of plant growth upon Earth.<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftn19" name="_ftnref19" title="">[19]</a><br />
<h1>
<span style="font-size: large;">Intention Is a Living Force of Physiology</span></h1>
Even human intention itself, the so-called ghost in the machine, may have an empirical basis in biophotons.<br />
A recent commentary published in the journal <em>Investigacion clinica</em> titled "Evidence about the power of intention" addressed this connection:<br />
<blockquote>
Intention is defined as a directed thought to perform a determined
action. Thoughts targeted to an end can affect inanimate objects and
practically all living things from unicellular organisms to human
beings. The emission of light particles (biophotons) seems to be the
mechanism through which an intention produces its effects. All living
organisms emit a constant current of photons as a mean to direct
instantaneous nonlocal signals from one part of the body to another and
to the outside world. Biophotons are stored in the intracellular DNA.
When the organism is sick changes in biophotons emissions are produced.
Direct intention manifests itself as an electric and magnetic energy
producing an ordered flux of photons. Our intentions seem to operate as
highly coherent frequencies capable of changing the molecular structure
of matter. For the intention to be effective it is necessary to choose
the appropriate time. In fact, living beings are mutually synchronized
and to the earth and its constant changes of magnetic energy. It has
been shown that the energy of thought can also alter the environment.
Hypnosis, stigmata phenomena and the placebo effect can also be
considered as types of intention, as instructions to the brain during a
particular state of consciousness. Cases of spontaneous cures or of
remote healing of extremely ill patients represent instances of an
exceedingly great intention to control diseases menacing our lives. The
intention to heal as well as the beliefs of the sick person on the
efficacy of the healing influences promote his healing. In conclusion,
studies on thought and consciousness are emerging as fundamental aspects
and not as mere epiphenomena that are rapidly leading to a profound
change in the paradigms of Biology and Medicine.</blockquote>
So there you have it. Science increasingly agrees with direct human
experience: we are more than the atoms and molecules of which we are
composed, but beings that emit, communicate with, and are formed from
light.<br />
<div>
<hr align="left" size="1" width="33%" />
<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftnref1" name="_ftn1" title="">[1]</a> Herbert Schwabl, Herbert Klima. <strong><a href="http://www.greenmedinfo.com/article/living-systems-give-measurable-intensities-light-ie-photons-visible-part-electromagnetic" target="_blank">Spontaneous ultraweak photon emission from biological systems and the endogenous light field.</a></strong> Forsch Komplementarmed Klass Naturheilkd. 2005 Apr;12(2):84-9. PMID: <a href="http://www.greenmedinfo.com/article/living-systems-give-measurable-intensities-light-ie-photons-visible-part-electromagnetic">15947466</a><br />
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<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftnref7" name="_ftn7" title="">[7]</a> B T Dotta, K S Saroka, M A Persinger. <strong><a href="http://www.greenmedinfo.com/article/increased-photon-emission-head-while-imagining-light-dark-correlated-changes" target="_blank">Increased
photon emission from the head while imagining light in the dark is
correlated with changes in electroencephalographic power: support for
Bókkon's biophoton hypothesis.</a></strong> Neurosci Lett. 2012 Apr 4 ;513(2):151-4. Epub 2012 Feb 17. PMID: <a href="http://www.greenmedinfo.com/article/increased-photon-emission-head-while-imagining-light-dark-correlated-changes">22343311</a></div>
<div id="ftn8">
<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftnref8" name="_ftn8" title="">[8]</a> I Bókkon, V Salari, J A Tuszynski, I Antal. <strong><a href="http://www.greenmedinfo.com/article/estimation-number-biophotons-involved-visual-perception-single-object-image" target="_blank">Estimation
of the number of biophotons involved in the visual perception of a
single-object image: biophoton intensity can be considerably higher
inside cells than outside.</a></strong> J Photochem Photobiol B. 2010 Sep 2 ;100(3):160-6. Epub 2010 Jun 10. PMID: <a href="http://www.greenmedinfo.com/article/estimation-number-biophotons-involved-visual-perception-single-object-image">20584615</a></div>
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<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftnref9" name="_ftn9" title="">[9]</a> Yan Sun, Chao Wang, Jiapei Dai. <strong><a href="http://www.greenmedinfo.com/article/biophotons-neural-communication-signals-demonstrated-situ-biophoton-autography" target="_blank">Biophotons as neural communication signals demonstrated by in situ biophoton autography.</a></strong> Photochem Photobiol Sci. 2010 Mar ;9(3):315-22. Epub 2010 Jan 21. PMID: <a href="http://www.greenmedinfo.com/article/biophotons-neural-communication-signals-demonstrated-situ-biophoton-autography">20221457</a></div>
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<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftnref10" name="_ftn10" title="">[10]</a> F A Popp, W Nagl, K H Li, W Scholz, O Weingärtner, R Wolf. <strong><a href="http://www.greenmedinfo.com/article/dna-may-be-source-biophoton-emission" target="_blank">Biophoton emission. New evidence for coherence and DNA as source.</a></strong> Cell Biophys. 1984 Mar;6(1):33-52. PMID: <a href="http://www.greenmedinfo.com/article/dna-may-be-source-biophoton-emission">6204761</a></div>
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<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftnref11" name="_ftn11" title="">[11]</a> Masaki Kobayashi, Daisuke Kikuchi, Hitoshi Okamura. <strong><a href="http://www.greenmedinfo.com/article/imaging-ultraweak-spontaneous-photon-emission-human-body-displaying-diurnal-rhythm" target="_blank">Imaging of ultraweak spontaneous photon emission from human body displaying diurnal rhythm.</a></strong> PLoS One. 2009;4(7):e6256. Epub 2009 Jul 16. PMID: <a href="http://www.greenmedinfo.com/article/imaging-ultraweak-spontaneous-photon-emission-human-body-displaying-diurnal-rhythm">19606225</a></div>
<div id="ftn12">
<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftnref12" name="_ftn12" title="">[12]</a> Masaki Kobayashi, Daisuke Kikuchi, Hitoshi Okamura. <strong><a href="http://www.greenmedinfo.com/article/imaging-ultraweak-spontaneous-photon-emission-human-body-displaying-diurnal-rhythm" target="_blank">Imaging of ultraweak spontaneous photon emission from human body displaying diurnal rhythm.</a></strong> PLoS One. 2009;4(7):e6256. Epub 2009 Jul 16. PMID: <a href="http://www.greenmedinfo.com/article/imaging-ultraweak-spontaneous-photon-emission-human-body-displaying-diurnal-rhythm">19606225</a></div>
<div id="ftn13">
<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftnref13" name="_ftn13" title="">[13]</a> Eduard P A Van Wijk, Heike Koch, Saskia Bosman, Roeland Van Wijk. <strong><a href="http://www.greenmedinfo.com/article/anatomic-characterization-human-ultra-weak-photon-emission-practitioners-transcendental" target="_blank">Anatomic
characterization of human ultra-weak photon emission in practitioners
of transcendental meditation(TM) and control subjects.</a></strong> J Altern Complement Med. 2006 Jan-Feb;12(1):31-8. PMID: <a href="http://www.greenmedinfo.com/article/anatomic-characterization-human-ultra-weak-photon-emission-practitioners-transcendental">16494566</a></div>
<div id="ftn14">
<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftnref14" name="_ftn14" title="">[14]</a> F W G Schutgens, P Neogi, E P A van Wijk, R van Wijk, G Wikman, F A C Wiegant. <strong><a href="http://www.greenmedinfo.com/article/rhodiola-reduces-level-biophoton-emission-human-subjects" target="_blank">The influence of adaptogens on ultraweak biophoton emission: a pilot-experiment.</a></strong> Phytother Res. 2009 Aug;23(8):1103-8. PMID: <a href="http://www.greenmedinfo.com/article/rhodiola-reduces-level-biophoton-emission-human-subjects">19170145</a></div>
<div id="ftn15">
<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftnref15" name="_ftn15" title="">[15]</a> H J Niggli. <strong><a href="http://www.greenmedinfo.com/article/experimental-model-using-artificial-sunlight-irradiation-induce-photon-emissions-human-skin" target="_blank">Artificial sunlight irradiation induces ultraweak photon emission in human skin fibroblasts.</a></strong> J Photochem Photobiol B. 1993 May;18(2-3):281-5. PMID: <a href="http://www.greenmedinfo.com/article/experimental-model-using-artificial-sunlight-irradiation-induce-photon-emissions-human-skin">8350193</a></div>
<div id="ftn16">
<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftnref16" name="_ftn16" title="">[16]</a> Hugo J Niggli, Salvatore Tudisco, Giuseppe Privitera, Lee Ann Applegate, Agata Scordino, Franco Musumeci. <strong><a href="http://www.greenmedinfo.com/article/laser-ultraviolet-induced-ultraweak-photon-emission-mammalian-cells" target="_blank">Laser-ultraviolet-A-induced ultraweak photon emission in mammalian cells.</a></strong> J Biomed Opt. 2005 Mar-Apr;10(2):024006. PMID: <a href="http://www.greenmedinfo.com/article/laser-ultraviolet-induced-ultraweak-photon-emission-mammalian-cells">15910080</a></div>
<div id="ftn17">
<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftnref17" name="_ftn17" title="">[17]</a> Janusz Slawinski. <strong><a href="http://www.greenmedinfo.com/article/photon-emission-perturbed-and-dying-organisms-biomedical-perspectives" target="_blank">Photon emission from perturbed and dying organisms: biomedical perspectives.</a></strong> Forsch Komplementarmed Klass Naturheilkd. 2005 Apr;12(2):90-5. PMID: <a href="http://www.greenmedinfo.com/article/photon-emission-perturbed-and-dying-organisms-biomedical-perspectives">15947467</a></div>
<div id="ftn18">
<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftnref18" name="_ftn18" title="">[18]</a> Cristiano M Gallep, Thiago A Moraes, Samuel R Dos Santos, Peter W Barlow. <strong><a href="http://www.greenmedinfo.com/article/coincidence-biophoton-emission-wheat-seedlings-during-simultaneous" target="_blank">Coincidence of biophoton emission by wheat seedlings during simultaneous, transcontinental germination tests.</a></strong> Protoplasma. 2013 Jun ;250(3):793-6. Epub 2012 Sep 26. PMID: <a href="http://www.greenmedinfo.com/article/coincidence-biophoton-emission-wheat-seedlings-during-simultaneous">23011402</a></div>
<div id="ftn19">
<a href="http://www.greenmedinfo.com/blog/biophotons-human-body-emits-communicates-and-made-light?utm_source=www.GreenMedInfo.com&utm_campaign=d4a7f2513a-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-d4a7f2513a-86792281#_ftnref19" name="_ftn19" title="">[19]</a> Peter W Barlow, Joachim Fisahn. <strong><a href="http://www.greenmedinfo.com/article/lunisolar-tidal-force-and-growth-plant-roots-and-some-other-its-effects-plant" target="_blank">Lunisolar tidal force and the growth of plant roots, and some other of its effects on plant movements.</a></strong> Ann Bot. 2012 Jul ;110(2):301-18. Epub 2012 Mar 20. PMID: <a href="http://www.greenmedinfo.com/article/lunisolar-tidal-force-and-growth-plant-roots-and-some-other-its-effects-plant">22437666</a></div>
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Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-50412166598159294662013-06-23T15:55:00.002-07:002013-06-23T16:17:48.428-07:00CLINICAL GUIDE to VITAMIN C<h1 align="center">
Clinical Guide to the Use of Vitamin C</h1>
<div style="text-align: center;">
<span style="font-size: large;">The Clinical Experiences of Frederick R. Klenner, M.D.,</span></div>
<div style="text-align: center;">
<span style="font-size: large;">abbreviated, sumarized and annotated by</span></div>
<div style="text-align: center;">
<span style="font-size: large;">Lendon H. Smith, M.D.</span></div>
<br />
<h4 align="center">
2233 SW Market Street, Portland, Oregon 97201</h4>
<br />
<hr />
<br />
<h3 align="center">
Preface</h3>
After Frederick Klenner died in 1984, his friend (and mine), Arthur Rybeck, a
nutritionally-oriented dentist practicing in Wheeling, West Virginia, asked if I would be
interested in going over the 27 papers Klenner had written from the early 1940’s to
the early 1970’s. The whole idea would be to let the world know how thoughtful and
careful a researcher he was, and to encourage others to continue his work. If a compendium
of Vitamin C (and other nutritional) therapy could be compiled from the published work of
Dr. Klenner, maybe we could get more traditional medicine-oriented doctors to use his
methods for the relief of sickness and suffering.<br />
<br />
Standard doctors tend to believe studies and reports if published, but tend to
disbelieve hearsay stories about treatments that patients have read in a
“health” newsletter.<br />
<br />
I have used Dr. Klenner’s methods on hundreds of patients. He is right. It helps
almost every condition and situation, and my failures were due to inadequate amounts.<br />
<br />
The timing of such a paper might be most appropriate. Doctors are suffering from low
public esteem because they are perceived to be money-grubbing and mistake-laden. This
would be a scientifically documented - from the medical literature - therapy for a variety
of conditions: cardiovascular, allergies, infections, malabsorption, (see index), and even
AIDS, for which prescription drugs may be hazardous. Now the doctors can say, “We
have a safe, reasonably natural way of treating your condition that is fairly cheap. We
might just keep you out of the hospital.”<br />
<br />
That last part might make the insurance carriers perk up their ears. The patients might
dash back to the doctors’ offices because the word is getting out that doctors are
helping people without side effects. Notice also, the dates on these articles and
references - these things were known decades ago.<br />
Take this booklet to your M.D. and suggest that he read about these documented studies.
Take Dr. E. Cheraskin’s “Vitamin C Connection” along for further
documentation. <b> </b><br />
<b>If your doctor doesn’t know, how can he help you?</b><br />
<br />
<hr />
<br />
<h3 align="center">
Foreword<br />
by Linus Pauling, Ph.D.</h3>
The early papers by Dr. Fred R. Klenner provide much information about the use of large
doses of Vitamin C in preventing and treating many diseases. These papers are still
important. Dr. Lendon Smith has done a valuable service in making the work of Dr. Klenner
available to the public.<br />
<br />
<hr />
<br />
<h3 align="center">
Introduction</h3>
I have before me the published words of Frederick Robert Klenner, B.S., M.S., M.D.,
F.C.C.P., F.A.A.F.P. He graduated from Duke University, School of Medicine back in 1936.
After three years of hospital training he entered the private practice of medicine in
Reidsville, North Carolina. His main subspecialty was diseases of the chest, but he became
interested in the use of massive doses of Vitamin C in the treatment of virus diseases and
other illnesses as well. He inspired Linus Pauling and Irwin Stone to expand the research
on the great benefits of Vitamin C. Dr. Klenner died in 1984.<br />
What follows is a review, and abbreviation, a summary and a critique of the 27
scientific papers he wrote. In the light of the recent developments and research in the
use of Vitamin C, it is essential that the roots of its usage be reviewed. Briefly,
Vitamin C does attenuate most virus infections by aiding the production of interferon,
controls many cancers, relieves some depression, modifies much pain and changes the course
of many diseases, like multiple sclerosis, amyotrophic lateral sclerosis, spider bites,
the bites of poisonous insects and reptiles. The watchword is, “If in doubt, give
Vitamin C.”<br />
<br />
<hr />
<br />
<h3 align="center">
Dedication</h3>
If Dr. Klenner had lived he would have wanted this book to be dedicated to the
following:<br />
Anne Klenner for her patience and understanding.<br />
Fritz for the lively discussions in chemistry.<br />
Mary Anne and Gertrude for being ‘guinea pigs’.<br />
<br />
<hr />
<br />
<h3 align="center">
General Remarks</h3>
He believed in the healing power of nature, but believed that natural remedies could
enhance that power and were safer and usual1y more effective than drugs. Hippocrates said,
“Of several remedies the physician should choose the least sensational”.
Vitamin C fills that criterion.<br />
<br />
In 1948, he published his first paper on the use of large doses of Vitamin C in
the treatment of virus diseases. In 1960, he realized, “Every head cold must be
considered as a probable source of brain pathology.” Hold on to this thought; it is
significant for the understanding of diseases like multiple sclerosis. He also
felt—as do Archie Kalikarinos and Glen Dettman of Australia—that the dreaded
Sudden Infant Death Syndrome was basically a Vitamin C deficiency. His maxim: the
patient should “get large doses of Vitamin C in all pathological conditions
while the physician ponders the diagnosis.”<br />
<br />
We have misled ourselves with the mistaken notion that all C was supposed to do was
keep us from scurvy. If, however, we base our needs on the amounts other mammals
manufacture with their intact enzyme it comes to 2-4 grams daily in the unstressed
condition. Under stress 70 kg of rats make 15 grams of C. [Burns; Salomon; Conney]<br />
<br />
We are willing to accept the premise that some of us are born with genetic defects that
lead to problems that can be somewhat controlled with diet and supplements (i.e.
phenylketonuria, galactosemia, and alkaptonuria and pernicious anemia). Can’t we
accept the fact that we all have a genetic deficiency of the enzyme, l-gulonolactone
oxidase and have to take Vitamin C for health, even for life? [Burns, 1959]<br />
<br />
Irwin Stone calls this human genetic lack, this inability, hypoascorbemia. The point
that Dr. Klenner is making: “The physiological requirements in man are no
different from other mammals capable of carrying out this syntheses.” If one is
anemic due to poor iron intake, is it cheating to swallow iron tablets for a while? If you
are hypoascorbemic because you cannot manufacture Vitamin C from sugar, extra glucose
in your diet will not help, you need to take Vitamin C.<br />
<br />
He reports that one of the Pilgrim Fathers wrote to a friend in England in 1621:
“Bring juice of lemon, and take it fasting. It is of good use.”<br />
<br />
Folklore has revealed to us what natural remedies have been helpful and even curative.
We have been lured into the trap of modern medicine which prescribed a drug for every
condition. But consider acerola: Puerto Rican legend has it that if the tree bearing this
fruit is in one’s backyard, colds will not enter the front door. This fruit bears 30
times the amount of C than oranges. Dr. Klenner credits Boneset with the health of
the Klenner family during the great influenza pandemic of 1918. This plant was made into a
tea, bitter but curative. He assayed the tea for Vitamin C; they were getting 10-30
grams at a time!<br />
<br />
The small amount of Vitamin C, recommended by the RDA (75 mg then and 60 mg now)
is enough to protect the person from gross disease, but not the amount to maintain good
health. Dr. Klenner quotes Kline and Eheart, who in 1944 realized there are wide
variations in the need for Vitamin C, in otherwise “normal” individuals. In
1945 Jolliffe suggested that the optimum requirements might be more than 10 times the
small doses recommended.<br />
<br />
Scurvy develops slowly. Crandon (in 1940) found that the Vitamin C level of the
blood plasma fell to zero for 90 days before there was obvious clinical evidence and that
this was as long as 132 days before the first signs appeared.<br />
<br />
<br />
<hr />
<br />
<h3 align="center">
How it Works</h3>
How does it work: as an oxidizing agent massive amounts, i.e., 5-150 grams,
intravenously, for certain pathological conditions, if allowed to run in rapidly (20 gauge
needle), acts as a “Flash Oxidizer” and may correct the condition in minutes. It
can be a reducing agent. It neutralized toxins, viruses and histamine. The more serious
the condition, the more C is required.<br />
<br />
It appears that Vitamin C acts as a reducing agent, an oxidizing agent, an
anti-clotting agent, an antihistamine, and as an anti-infective agent.<br />
<br />
He summarized the function of C in poliomyelitis:
<br />
<br />
<ol>
<li>Virus destruction.</li>
<li>Dehydrates the brain and the spinal cord safely.</li>
<li>Supports and normalized the stressed adrenal glands.</li>
<li>It preserves the lining of the central canal and maintains more regular spacing and less
crowding of ependymal cells (surface cells of the spinal cord).</li>
</ol>
Ascorbic acid enters all cells. It “proceeds to take up the protein coats being
manufactured by the virus nucleic acid, thus preventing the assembly of new virus
units.” Cells expand, rupture and die, but there is no virus particles available to
enter and infect new cells. If a virus has invaded a cell, the Vitamin C contributes
to its breakdown to adenosine deaminase, which converts adenosine to inosine. Purines are
formed which are catabolized (broken down) and cannot be used to make more virus nucleic
acid.<br />
<br />
Viral nucleic acid has a protein coat which protects this parasite as it rides the
blood or lymph highway to gain specific cell entry. [Larson] it is possible that if the
ascorbic acid can remove that protective protein coat in the blood stream or in the cells,
the white cell phagocytes and immune globulin could then neutralize these vulnerable virus
particles.<br />
<br />
I like this from Dr. Klenner: “Ascorbic acid also joins with the available
virus protein, making a new macromolecule which acts as the repressor factor.”
(interferon?) Multiplication of new virus bodies is inhibited.<br />
<br />
He summarizes the study of Lojkin, (1937), who discovered the inactivation of one virus
was due to a specific intermediate product formed in the course of the oxidation of C but
needed the stimulation of copper ions. It is a peroxide and is decomposed as rapidly as it
is formed. This study indicates why Vitamin C works better in the body and not the
test tube. Every function of the body requires enzymes, some vitamins and some minerals to
act as coenzymes. If enough Vitamin C is supplied, the enzyme system that breaks down
invading viruses and bacteria, will be able to do its job properly. Quote: “Unless
the white blood cells are saturated with ascorbic acid, they are like soldiers without
bullets.”<br />
<br />
Vitamin C <i>in vitro</i> at body temperature inactivates certain toxins at
an unbelievable rate. Back in 1938 some researchers [Klegler] placed Vitamin C in
test tubes with toxins. After incubation for 48 hours the toxins were not lethal to mice
when injected. The more toxin in the tube, the faster the C disappears. “The rate of
disappearance of the C in toxin and ordinary broth was more striking the greater the
concentration of Vitamin C.” Dr. Klenner concluded: “The degree of
neutralization in a virus infection will be in proportion to the concentration of the
vitamin and the length of time which it is employed.”<br />
<br />
This has been Dr. Klenner’s main complaint: failure to benefit from
Vitamin C use is usually due to inadequate amounts being used for too short a period
of time.<br />
<br />
Vitamin C combines directly with the toxin/virus. This new compound is oxidized by
Vitamin C; the toxin/virus and the Vitamin C are destroyed. This must be why C
has to be continued after the apparent cure.<br />
<br />
It acts as a respiratory catalyst, aiding cellular respiration by acting as a hydrogen
transport. The liver has a better chance of detoxifying the blood stream of poisons,
toxins, viruses and bacteria if the plasma is saturated with Vitamin C. Fever, toxins
and bacteria reduce the level of C. Therefore, Dr. Klenner theorizes, if a high level
of C is maintained, all tissues return to normal despite the fever and the bacteria; and
because of its action “as a respiratory catalyst, it enables the body to build up
adequate resistance to the invader.”<br />
<br />
The anaerobic condition in the tissue is relieved. Acidity is decreased and large
amounts of Adrenaline disappear. The constriction of the blood vessels ceases and the
liver and pancreas can receive the proper nutrients to function. Properly calculated doses
of C on a continuing basis will restore the normal physiology of the body.<br />
<br />
The adrenals and Vitamin C are interrelated. During an infection Vitamin C is
absent from the urine and is decreased or absent in blood, even when moderate amounts are
being given intravenously. Vitamin C in the adrenal glands was greatly reduced in
animals succumbing to polio. (Dr. Klenner cites the literature of 1934-35 to document
this.) Hans Selye knew how the adrenals would show damage with stress. He found that all
patients ill with a virus would show petechial hemorrhages (small leaks of blood into the
skin) when a tourniquet was applied to increase venous backpressure. Capillary weakness is
a sign of low levels of Vitamin C. Sugar in the urine, associated with the petechiæ,
disappeared when adequate serum levels of Vitamin C were obtained.<br />
<br />
It is known the C regulates the intercellular substance of the capillary wall. The
collagen of all fibrous tissue structures is dependent on an adequate level of
Vitamin C. Increased capillary fragility is observed in individuals when the blood
level of C drops to 1 mg per liter. These weak capillary walls may allow a simple virus to
invade the brain (see “Insidious Virus”).<br />
<br />
In addition, Vitamin C acts as catalyst in the assimilation of iron.<br />
<br />
(Ascorbic acid is a necessary coenzyme in the metabolic oxidation of tyrosine. The
latter is necessary to break down protein to a usable amino acid.)<br />
<br />
Dr. Klenner states, “The importance of Vitamin C as an antibiotic and as
the precursor of antibody formation lack scientific appreciation because of its
simplicity.” The reluctance of the medical profession to employ it in massive doses
like antibiotics has allowed the appearance of allergies as a major problem.<br />
<br />
Vitamin C is known to be essential for life. He quotes the studies that show that
when Vitamin C is given intravenously to patients with a deficiency, fibroblasts
begin to form connective tissue and capillary buds invade blood clots within just a few
hours. In a similar time frame when used as an antibiotic, fever falls and the white count
climbs.<br />
<br />
Dr. Klenner points out that the standard treatment of colds was based on the
alkalinizing effect of forcing juices down the patient’s throat. Highly alkaline
urine has less Vitamin C. The Vitamin C would be thus retained in the tissues
helping to guard against the viruses and bacteria. When Vitamin C levels drop,
glycogen in the liver is converted to glucose: a response to stress.<br />
<br />
Dr. Klenner is convinced that C will work in any problem but the negative results
reported are only because an insufficient amount was used. A tragic error in judgment has
been made by the National Academy of Science and the National Research Council: the
minimum daily requirement for C. All of us need more; some need a lot more.<br />
<br />
Factors that determine need:
<br />
<br />
<ol>
<li>age</li>
<li>habits, alcohol, drugs, tobacco</li>
<li>sleep, especially if drugged</li>
<li>trauma of infection, of physical injury, of work, of emotions, of surgery</li>
<li>Kidney threshold</li>
<li>environment</li>
<li>physiological stress</li>
<li>climate changes</li>
<li>loss of C in stools</li>
<li>absorption</li>
<li>binders in tablets</li>
<li>individual difference in body chemistry</li>
<li>drugs, pesticides, carbon monoxide exposure</li>
<li>weight</li>
<li>poor storage.</li>
</ol>
Klenner quotes the Food and Life Year Book, 1939, published by the U.S. Department of
Agriculture (surely as conservative and orthodox a group as one could ever find):
“Even when there is not a single outward symptom of trouble, a person may be in a
state of Vitamin C deficiency more dangerous than scurvy itself. When such a
condition is not detected, and continues uncorrected, the teeth and bones will be damaged,
and what may be even more serious, the blood stream is weakened to the point where it can
no longer resist or fight infections not so easily cured as scurvy. Five grains of aspirin
will not relieve kidney colic; don’t expect control of a virus with 100 to 400 mg of
C.”<br />
<br />
<hr />
<br />
<h3 align="center">
Dosage</h3>
The amount of C depends upon the severity of the disease but also upon the efficiency
of the victim’s immune system. The usual dose of 65 mg per kilogram of body weight
may be expected to take care of the usual virus infection when given every 2-4 hours by
needle. The more severe condition would respond to larger single injections.<br />
<br />
However “if the activity of the pathogen is completely stopped, the development of
active immunity will be interrupted.” Therefore, modification of childhood diseases
is the aim of Vitamin C treatment, not the complete overnight suppression that would
prevent the body from making immune memory. To accomplish modification, 250 mg per
kilogram should be given intramuscularly. If necessary, half of this amount would be given
in eight hours. Procaine 1.5-2% can be given with a separate syringe with the same needle
just prior to the C.<br />
<br />
The itch, the irritability, the pain, the vomiting of chicken pox measles and mumps was
assuaged in one hour with this last dose. Crusting of chicken pox was present in 5 hours
instead of 7-9 days. 250 mg per kilogram eliminated the disease in contrast to the 65 mg
which just suppressed it. 350 mg per kilogram may be employed along with antibiotics in
treating stubborn bacterial infections. Because a virus infection will deplete the
Vitamin C reserve, bleeding from the nose or chest would indicate an emergency
situation; Vitamin C, using the above noted dosage schedule, should be pumped in
immediately.<br />
<br />
He cites experimental work by others indicating that in monkeys smaller doses of C
could stop the disease from appearing during the incubation period compared to the
relatively large doses needed to suppress the disease once the disease was diagnosed. It
all suggests that most of us will not get any serious virus disease if we would all take
sufficient Vitamin C daily. We need, however, to get a little sick so we will develop
some immunity, but if we get very sick a lot there is something missing, usually
Vitamin C. He is suggesting that the more serious the disease, the more
Vitamin C should be used to treat it. (We titrate the sickness, as Dr. Cathcart says:
“Well, you’ve got a 200 gram flu or a 50 gram cold.)<br />
<br />
In Dr. Klenner’s review of his over 3000 cases about 15% required more
Vitamin C than the average. This ties in with the idea that we are all different. It
also explains why some dogs, who make their own Vitamin C would die of distemper.
“I have cured many dogs suffering with distemper by giving several grams of ascorbic
acid, by needle, every two hours.” 15% of 300 obstetrical cases required 15 grams of
C daily to remain within normal limits. The other 85% needed only 10 grams per day. He
felt some spillage into the urine indicated the body was saturated. “White blood
cells are useless unless they are full of ascorbic acid.”<br />
<br />
Dr. Klenner argues that the recommended daily allowances are only to prevent
scurvy. “Acute scurvy and chronic hypovitaminosis are metabolically different
conditions.” We all are much more vulnerable to stress, infections, and pollution.<br />
<br />
A shortage is produced from a poor diet but also poor hygiene, overcrowding, dampness,
cold and physical work (or play). There is a narrow margin between health and pathological
changes.<br />
For a very severe illness, the dose he used was large and the most effective route was
intravenous, but the intramuscular route was satisfactory. He gave at least 350 mg per
kilogram of body weight. (A 70 kg man is 150 pounds; thus 70 x 350= 24,500 mg. He would
use a 25 gram dose for a 25 gram illness.) This amount was put in 500 cc of sterile water,
usually with dextrose, saline or Ringer’s solution. It was diluted so that there was
at least 18 cc of diluent to each gram of C. In small children, 2 or 3 grams can be given
intramuscularly once every two hours. An ice cap to the buttocks will prevent soreness and
induration. As much as 12 grams can be given in this manner into 2 or 3 different muscle
sites with a 50 cc syringe; larger amounts must be diluted with dextrose or saline and run
in by I.V. drip. If big concentrated doses are given by push (25 grams in a 100 cc
syringe), the brain may become dehydrated causing convulsive movements of the legs.
Intramuscular injections are always 500 mg to 1 cc solution. At least one gram of calcium
gluconate must be added to the fluids each day. Massive doses of C pull calcium ions from
platelets; and the clotting mechanism is weakened. Nosebleeds may occur. One gram of
calcium gluconate is added to control acidity and to replace the calcium ion loss.<br />
<br />
Sodium ascorbate is less painful. Some of us will put procaine, 2%, with the
Vitamin C when injected into the muscle. Vitamin C can also be taken orally once
the patient is recovering.<br />
<br />
This dose is repeated every hour for 6 to 12 times and then every 2-4 hours until
recovery.<br />
If using under 400 mg per kg body weight, it can be given with the sodium salt. Doses
over 400 mg per kg of body weight must be diluted to at least one gram to 18 cc of
solution.<br />
<br />
He suggests the following for each bottle: 60 grams of C, 500 mg thiamin HCl, 300 mg
pyridoxine, 400 mg calcium pantothenate, 100 mg riboflavin, 300 mg niacinamide. It is to
be given once or twice daily.<br />
<br />
He used a 23 gauge needle intravenously and a 22 gauge needle for intramuscular
use—one inch long for children and one and a half inch for adults.<br />
<br />
The idea of these big doses is to saturate the tissues; the white blood cells will be
able to destroy pathogens. “I have seen diphtheria, hemolytic streptococcus
infections clear within hours following an injection of ascorbic acid in a dose ranging
from 500-700 mg per kilogram of body weight given intravenously as fast as the
patient’s cardiovascular system will allow.”<br />
<br />
He got to know the vulnerability of viruses so well, he played games with them.
“When proper amounts are used it will destroy all virus organisms.” He could
give one gram of ascorbic acid every four hours and modify the disease symptoms, but if he
gave one gram every two hours by mouth for four days, he had stopped the disease,
apparently by killing the virus. If he gave this dose for only two days, the symptoms
returned. (He kept measles simmering in his own children for a month by giving this dose
for two days, then off for two then on, etc.)<br />
<br />
With 350 mg per kilogram of body weight every two hours, he could stop measles and dry
up chicken pox. If he could get in the vein, 400 mg per kilogram two to three times in 24
hours was all that was required (he published this way back in 1951, in the Southern
Medical Surgical Journal).<br />
<br />
He used protamide and it seemed to shorten the course of the course of the disease (it
is a colloidal solution of denatured proteolytic enzyme). It was especially valuable in
herpes simplex and herpes zoster. Dr. Klenner felt that Vitamin C is related to
this enzyme, as it possesses the same anti-neuritic properties. If used together, the
results are more dramatic than either one used alone (the C was used as usual and the
protamide was limited to one ampoule per day). Influenza and poliomyelitis also responded
rapidly to this dual approach. He found calcium made a big difference as it duplicated the
results of the C. He used 10 cc of calcium gluconate (one gram of calcium) along with the
C daily. It can also be injected deep into the gluteus muscle.<br />
<br />
<hr />
<br />
<h3 align="center">
Tests for C</h3>
He noted a monitoring method: “In all virus infections the Benedict urine reaction
for sugar will run from two to four plus. After Vitamin C, this reaction will clear
in 18 to 36 hours.” We all know that Vitamin C is related to glucose and
Vitamin C in the urine will show a reducing reaction, just as glucose does. If a
healthy individual is given one or two grams of C by injection, the urine will show a
positive Benedict sugar reaction for hours.” This paradox, Dr. Klenner explains,
indicates that Vitamin C and the virus bodies do form a new compound, and not a
reducing chemical, otherwise with all this Vitamin C injected, there would be an
increase in the response to the Benedict test.<br />
When the urine starts to show a positive test to Benedict’s test, it is a sign
that the virus is under control and the person is close to normal again. The
Benedict’s urine test is a guide to treatment with C.<br />
<br />
More than 30 years ago, Dr. Klenner developed the silver nitrate urine test. When
treating severe pathological conditions, the test done every four hours will reveal the
level of Vitamin C saturation. If the urine test is positive for Vitamin C, it
means the tissues are saturated and the patient is on the right dose. It is not a waste;
some spillage indicates saturation.<br />
<br />
<hr />
<br />
<h3 align="center">
Insidious Virus</h3>
In June, 1957, he wrote in the Tri-State Medical Journal, on the ‘Insidious’
virus. He recalled a 19 month-old baby, who had a minor cold for two weeks. Then suddenly,
instead of getting well, he developed a high fever and seizures of his right arm and leg.
He was stiff, undernourished, cold to the touch and semi-comatose. Two grams of C were
injected on admission to the hospital and another gram within the hour. Then it was one
gram orally every four hours. Mustard plasters and croup tent were provided. A cup of
orange juice was drunk from a bottle two hours after the first shot. The baby began to
respond to pain. Temperature was still high, 103.8°. The arm and leg were completely
paralyzed, but in eight hours, he began moving the right leg and could hold the juice
bottle with both hands. Penicillin “was given on the second and third days to
discourage secondary invaders”. He was home on the 5th day.<br />
<br />
Dr. Klenner recalls six additional similar cases, all under four years of age.
Four of the children were seen by a physician who noted no fever and was “not
impressed with the illness of the child.” All of these children died within 30
minutes to two hours after that physician’s examination. No treatment was begun
because there was no diagnosis. A virus infection was found at the autopsy. “An
insidious virus involvement of the brain.”<br />
<br />
He takes us through the examination and treatment of a near miss. An eighteen month-old
girl had a cold for a week; then choked on supper. Her temperature was normal, but she was
very restless and whining. On a hunch, Dr. Klenner sent her to the hospital. She was
comatose on arrival, responding only to pain. Temperature still normal, but pulse was 152
and respirations 32 per minute. He felt she had the “Insidious Virus” and
started Vitamin C. Two and one half grams initially intramuscularly; in 30 minutes
she got another two grams. Then every two hours for five doses and then every four hours.
After 36 hours, it was injected every six hours. (30 grams altogether). Croup tent and
penicillin were used.<br />
<br />
Shortly after admission, some water by mouth was tried and she immediately choked, and
the water came out of her nose—like bulbar polio. The normal temperature at admission
slowly rose to 102.4°. Six hours after admission, she was able to swallow. By the 11th
hour the temperature was normal and she was alert and swallowing. In 24 hours from the
first dose of C she was drinking freely from a bottle. She went home on the fifth day.<br />
<br />
Dr. Klenner feels if she had been put to bed after supper that night, she would
have died in her sleep, like a case of Sudden Infant Death Syndrome. He calls it brain
pathology caused by an insidious virus.<br />
<br />
Dr. Klenner was reminded of the case of a 15-year old girl who had had a lingering
cold for several weeks. She complained of extreme fatigue at a dance party, but other than
that and her cold symptoms, she went to bed apparently well. The next morning she was
found dead. The autopsy was virus pneumonia. Dr Klenner believed that the lung pathology
was not enough to kill her, it was the insidious virus that invaded her brain. He feels
that the motor nuclei have the shortest nerves, therefore the virus would reach them
first. It could lead to spasm of the diaphragm muscle and cessation of breathing.<br />
<br />
He felt that ascorbic acid could not reverse the virus once the pathology had
progressed to a certain unknown point. He feels this maxim should guide all treating
doctors: large doses of Vitamin C should be given in all pathological states,
“It should be given by all physicians while they await the diagnosis.”<br />
<br />
These large doses should be reduced once the temperature approaches normal; false
temperature rise may result. If the C is taken from the ampoules and swallowed in some
juice, it will have about the same results as if it had been injected.<br />
<br />
In another similar paper published the next year, 1958, in the Tri-State Medical
Journal, he outlines two important stages:<br />
<br />
Stage (A):<br />
<br />
1) a history of having had the flu for two or three days complicated by
physical or mental stress, or<br />
<br />
2) a mild cold with a runny nose for several weeks.<br />
<br />
Then the
sudden onset of Stage (B) with either 1) convulsions, 2) extreme excitability or dancing
eyeballs, 3) severe chill, 4) strangling during normal swallowing, 5) Collapse or stupor.<br />
<br />
Stage (B) is usually associated with the following:
<br />
<br />
<ol>
<li>rapid pulse,</li>
<li>normal or moderately elevated temperature,</li>
<li>respirations twice the normal rate and sometimes an air hunger (which is reminiscent of
that seen in acidosis or aspirin poisoning),</li>
<li>dilated, unequal pupils,</li>
<li>normal urinalysis,</li>
<li>elevated white blood count (which elevation is usually associated with a bacterial
infection),</li>
<li>normal bowel action,</li>
<li>loss of bladder control when convulsions or coma occurred.</li>
</ol>
He felt that the rapid spread of the virus to the brain tissue was similar to the speed
of the onset of the symptoms after a severe head injury: “... a margin of safety is
so narrow that life and death are separated only by minutes.” There is no time to
wait for the laboratory results.<br />
<br />
Case I: A 64-year old woman had a slight cold for a week, but no other symptoms. She
suddenly developed 104° (axillary) and slipped into a coma (pulse 120). In the hospital
she received achromycin and ascorbic acid. Dr. Klenner put 26 grams of C into 375 cc
of 5% dextrose in water, and let it drip intravenously, 75 drops per minute. An oxygen
mask was applied. The white blood count was 18,000.<br />
<br />
She became conscious an hour after this was begun but could not swallow and was
incontinent. The fever dropped to 102°, but by the ninth hour it was again at 104°.
Another I.V. was given (the same as above) with the antibiotic, and the 26 grams of C was
begun—R=36 per minute.<br />
<br />
In another hour (24 hours after admission) her temperature was 100°, pulse 84, and
respiration 28. By noon the next day (36 hours) she was suddenly able to swallow again.
She continued the achromycin daily and four grams of Vitamin C orally every four
hours.<br />
<br />
Case II: A five-year old boy with no special symptoms suddenly developed a convulsion
and 104° (rectally), pulse 130 and respiration 18. He was extremely restless. His throat
was red and white count 9,000. He had another convulsion in Dr. Klenner’s
office. Dr. Klenner gave him four grams of C intravenously and sent him into the
hospital where he got three grams of C intramuscularly. His dose was then four grams of C
in orange juice every four hours, plus an antibiotic (chloromycetin, rarely used now).
Temperature was normal in 12 hours. He continued treatment at home for three days.<br />
<br />
Case III: A 16 month old boy who had had a mild cold for two weeks suddenly collapsed
into unconsciousness. The pulse was over 200, and respiration 40 per minute and
temperature 100° rectally. Oxygen was started and two grams of C was given
intramuscularly. He roused in ten minutes. Two grams of C was given every two hours for
five times, then every four hours for twelve more doses. The examination and white blood
count (10,000) indicated bilateral pneumonitis so achromycin was added (50 mg every four
hours). The temperature was normal by the third day. And he was home in a week.<br />
<br />
Case IV: A two-and-a-half-year old boy had a lingering cold for ten days. Temperature
was 101° with red swollen tonsils. Ears and chest clear, but the pulse was 130 and
respirations were rapid and labored. He was sent home to have some prescriptions filled
but had a convulsion at the pharmacy and was brought back. Temperature then was 103°. He
received three grams of C intramuscularly plus oxygen. At the hospital he was given
another two grams of C. It was repeated in one hour and then every two hours x 4.
Penicillin was administered along with terramycin. His temperature was normal in eight
hours after admission and remained so; he was taking and retaining fluids. He was home on
the second hospital day.<br />
<br />
Case V: Demonstrates the usual quick response to therapy, but also the recurrence rate
if the C is discontinued prematurely. The patient, a 73 year-old male, was admitted three
times in 24 days with the same disease. He had a slight cold for a few days. Then
abruptly, a severe headache was followed by a chill and coma. T=103, p=138, resp.=36,
BP=150/90, white blood count was 10,000. Moisture was detected in his lungs. Muscle jerks
appeared. Nasal oxygen begun. Intravenous achromycin and Vitamin C were begun; 20
grams of C was added to 378 cc of 5% dextrose in water. It was repeated in eight hours. He
became conscious in 18 hours. He went home on the third day but returned in two weeks with
the same findings and received the same treatment and sent home. In seven days he was back
with the same symptoms. He was given 24 grams of C and sent home on achromycin and ten
grams of C daily indefinitely.<br />
<br />
As these cases show Dr. Klenner was confident that the C would handle the virus,
but he needed the antibiotics to control the bacterial secondary invaders.<br />
<br />
The initial dose administered by needle is no less than 250 mg per kilogram of body
weight. For children the dose would be two to three grams intramuscularly using a
concentration of 500 mg per cc. Ice on the muscle after injection will usually control
pain. “Massive use of C is compatible with any other drug and in most instances it
will enhance the value of these other remedies.”<br />
<br />
He felt that the virus (or their toxins) act on the brain and can culminate in
diaphragmatic spasm with resultant dyspnea and even asphyxia.<br />
<br />
He believed that the lingering “cold” had depleted the stores of
Vitamin C. The capillary beds in lungs and brain are damaged and the virus can invade
these tissues. The microscopic pathology in the brain shows thrombosis of vessels,
hemorrhages and proliferation of leucocytes. These are signs of ascorbic acid deficiency.
If the patients are not given massive doses of C at this critical time, they will
experience permanent nerve injury or may succumb. Pregnant women are thus more susceptible
to polio because of their relatively low stores of C. “With the use of massive doses
of Vitamin C, I have yet to see a patient not fully recovered.” It will also
shorten the illness by at least one-half the usual sickness days, and the patients can be
easily handled at home. Indeed, he treated many of these patients with two and three
visits a day in the office for the Vitamin C shots. He did not exclude the use of
antibiotics.<br />
<br />
In 1960 he reemphasized the need for families and physicians to be vigilant for the
potentially fatal viral encephalitis. As published in The Tri-State Medical Journal,
February, 1960, he warned that “every cold must be considered as a probable source of
brain pathology.” Most doctors are not impressed with the seriousness of the runny
nose, the sore windpipe and the dry cough until this smoldering virus bursts through the
defenses and attacks the brain.<br />
<br />
The point he is emphasizing is that the smoldering virus is depleting the circulating
Vitamin C, and when it gets low enough, the intercellular cement is weakened; the
virus can easily burst through to the susceptible brain. It is like a metastasis of the
pulmonary pathology to the brain (just like cancer cells seeding into the brain).<br />
<br />
The brain is the logical target of any virus floating about in the blood, as the
vascular system supplying the brain is the most extensive of all the capillary beds in the
body. Interference with the blood supply of the nervous system can be disastrous, since
the brain cannot accumulate an oxygen debt.<br />
<br />
Biochemical techniques will some day indicate what is happening at the cellular level.
The proof lies in the results. Dr. Klenner recites some classics way back in 1953. A
patient with virus pneumonia and a fever of 106° received 140 grams of C over a period of
72 hours. On the third day she was alert, sitting in bed and swallowing fluids by mouth.
Dr. Klenner believed that a similar respiratory virus in a baby with a truncated
immune system might spread all over the body in minutes winding up in the brain as
encephalitis, pneumonia and diaphragmatic spasm. (The Sudden Infant Death Syndrome
(S.I.D.S.) that takes 8,000 babies in the U.S. between ages two and ten months of age.)<br />
<br />
It is not just the lung pathology that takes these people; it is the brain invasion.
(It sounds a little like Reye’s syndrome—an innocent flu turns into a fatal
encephalitis.) “It is necessary for everyone to take adequate supplemental
Vitamin C to guard against such disasters.”<br />
<br />
He had searched the literature and found studies reported in 1905 and 1907 that
confirmed the virus lung-to-brain encephalitis pattern. All of Dr. Klenner’s
patients recovered. How do we get doctors to inject massive doses of C into their
collapsed patients while they are “pondering the diagnosis?”<br />
<br />
He felt there were many pathways into the brain: nose, stomach, ears but the basic
fault might be the breakdown of the intercellular cement of the capillary wall in
regulating the permeability of the blood vessels of the C.N.S. Vitamin C is essential
to the integrity of those capillary walls. It makes sense to believe that the chronicity
of the virus infection—mild though it may have been—could have finally depleted
the body of an optimum supply of C for maintenance of tissue repair. Capillaries break
down, blood and viruses are free to attack the brain. The theory and practice seem to fit.
Vitamin C helps control virus infections, and if there is a failure, usually it is
because not enough C was being used.<br />
<br />
In another case, a seven year-old boy was treated for influenza off and on for six
weeks. He got sulfa, a form of penicillin and five to ten grams of C orally. When he had
the fourth recurrence, the antibiotics and C had no effect. On the third day he suddenly
became lethargic and then dropped into a stupor. Temperature was 102.6°. Dr. Klenner
quickly injected him with six grams of ascorbic acid intravenously. In five minutes he was
awake, asking, “what happened?” Another six grams in four hours and two more at
six hour intervals. Recovery complete in 24 hours without a trace of recurrence. The
patient was administered five grams of C in juice every eight hours for a week. The
patient was Dr. Klenner’s son.<br />
<br />
Viral encephalitis can be associated with cold sores; one third of patients die and 85%
of survivors have brain damage. All of us are infected by the age of five years but only
1% experience symptoms. The virus is harbored in a dormant form until a physical or
emotional hurt provokes the virus to reproduce and manifest itself with the canker sore.<br />
<br />
<hr />
<br />
<h3 align="center">
Virus Pneumonia</h3>
He wrote an article about virus pneumonia (Southern Medicine and Surgery, Feb. 1948), a
persistent debilitating illness that responds poorly to antibiotics. In his series of 42
cases he achieved excellent results with, surprisingly, Vitamin C. Some doctors were
using X-rays as therapy!<br />
<br />
His routine: 1000 mg of Vitamin C intravenously every six to twelve hours for a
mild case. In children, 500 mg of C intramuscularly every six to twelve hours was about
right. Three to seven injections were all that was required for complete clinical and
X-ray resolution. Most patients felt better in just one hour and definite improvement
after two hours. Nausea and headache disappeared after the first shot. Fever fell at least
two degrees Fahrenheit in several hours after the first injection.<br />
He gave alkaline drinks as this impedes the excretion of the C through the kidneys.
Mustard plasters were used to relieve chest pain and constricted breathing. In some
patients cyanosis (blueness due to lack of oxygen in tissues) was immediately relieved by
an additional injection of 500 mg of C.<br />
<br />
He then reports the case of virus pneumonia which he treated in the early 1940’s.
The man became blue but refused to be hospitalized; Dr. Klenner wanted to test the
catalytic action of Vitamin C to serve as a gas transport (O<sub>2</sub>) aiding
cellular respiration. He gave him two grams of Vitamin C intramuscularly and the
cyanosis began to clear up in 30 minutes. Six hours later that patient was sitting up
eating dinner; his fever had fallen three degrees. Dr. Klenner suspected that the C
had done more than act as a respiratory catalyst. He was given a gram every six hours for
three days. He was well by this time. Here is “evidence to prove unequivocally that
Vitamin C is the antibiotic of choice in the handling of all types of virus diseases.
Furthermore, it is a major adjuvant in the treatment of all other infectious
diseases.”<br />
<br />
Virus Pneumonia: female, 28 years, temperature = 106°, chest and head cold two weeks,
severe headache, stuporous, dehydration. Antibiotics were of no help.<br />
<br />
Treatment: 1000 cc of 5% dextrose in a saline solution and four grams of C. Temperature
to 100° in eleven hours. Then every two to three hours—two to four grams of C was
given intravenously. At 72 hours the patient was alert, sitting up and swallowing fluids.
Vitamin C treatment was maintained for another two weeks: two grams every twelve
hours. Thiamin was given for deafness (due to previous antibiotics and encephalitis);
hearing normal in ten days. X-ray did not clear up for another two to three months.<br />
<br />
In a 58 year-old man with a severe viral pneumonia only one-half the recommended dose
was used (two grams every four hours). He slowly improved (three grams in six hours). His
dose should have been four grams every four hours or two grams in two hours. “The
course emphasized the necessity of administering massive doses of C at frequent regular
intervals so as to maintain the proper level of this ‘antibiotic’ in the
tissues.”<br />
<br />
Dr. Klenner points out, as all doctors know, a secondary infection frequently gets in
“on top” of the original virus infection. Virus pneumonia very commonly allows a
germ to produce a bronchitis, requiring an antibiotic.<br />
<br />
<hr />
<br />
<h3 align="center">
Poliomyelitis</h3>
In polio, Vitamin C destroys the virus, acts as a diuretic removing the edema of
the brain and prevents crowding of the cells lining the nervous system (see p. 2). The
swollen, infected tissue creates a pressure in the unyielding bony vault and cuts off the
blood supply to the motor cells, thus paralysis follows.<br />
<br />
Dr. Klenner reports the findings of a Dr. McCormick who attended 50 cases of polio
in Toronto, Canada (1949). The polio victims who were white bread eaters developed
paralysis, but the brown bread eaters were protected from paralysis. B vitamins seem to
give anti-paralysis protection. The Vitamin C relieves the pressure on the vessels so
the nutrient—including B<sub>1</sub>—can nourish the cells properly.<br />
<br />
He reports the case of a five year-old girl with paralysis of both legs accompanied by
knee and back pain. Massage was given along with Vitamin C by injection. Within four
days she was able to move both legs. She was sent home to continue the Vitamin C
orally at 1000 mg every two hours. She walked by the eleventh day; the vitamin was stopped
and B<sub>1</sub> begun, only ten milligrams four times each day. She was completely well
by the 19th day after treatment had been started.<br />
<br />
Another polio case with 104.4° temperature (measured in the armpit) severe headache,
red eyes, vomiting and tightness in the hamstrings. Two grams of Vitamin C was given
intravenously immediately and again in two hours; then every four hours for 48 hours. In
six hours after the first intravenous dose, his temperature had fallen to 100°, his eyes
cleared up, he was jovial, sitting and drinking fluids. He would have them on 1500 mg of C
by mouth every two hours for a week. The C was discontinued, and he took 25 mg of B<sub>1</sub>
four times a day. Dr. Klenner felt B<sub>1</sub> should be continued for a period of
at least three months because nerve tissue is slow to recover.<br />
<br />
In another article about viruses in 1949 (Southern Medicine and Surgery, vol. 111, #7,
July) he states his frustration at the lack of ability of standard researchers to
recognize their failure in treating viral diseases; they did not give big enough doses
frequently enough. He found an unbelievable record of these failed studies in the ten
years before he wrote this article.<br />
<br />
He concentrated on the response of poliomyelitis to Vitamin C in this article. He
knew that the virus was floating about in the blood stream and that large doses of
Vitamin C would destroy the virus before it got to the nervous system.
Dr. Klenner reviewed the literature in 1948 because he was having consistent,
positive responses with Vitamin C; he was encouraged when he read that some
investigators had discovered low levels of C in the urine of humans and animals when
infected with the polio virus. He felt there was a “relationship between the degree
of Vitamin C saturation and the infectious and noninfectious state.” An
Australian, Heaslip, showed a “correlation between the severity of the attack and the
level of urinary excretion of the vitamin.” A “deficiency of Vitamin C in
the diet predisposed to infection and to the severity of the attack.”<br />
<br />
One report he cited was published by Jungeblut in 1937. If Vitamin C was given
during the incubation stage in monkeys, the subsequent disease was much less severe. But
if the disease was in its fifth day, much larger doses of C were required. Even when but
100 mg of C were given in 24 hours to these experimental monkeys, there were six times the
number of non-paralytic survivors as in the control group.<br />
<br />
Dr. Sabin attempted to discredit the use of Vitamin C in controlling polio in
monkeys but did not give enough (100mg), and the monkeys had unmodified poliomyelitis.
Scurvy is surely an invitation to infection, but the absence of scurvy does not assure an
adequate immune system—especially when an infection invades. Malnutrition plays a
definite role in susceptibility to virus infections. “Thousands of children owe their
paralyzed limbs to this unfortunate blunder of Sabin.”<br />
<br />
He arbitrarily adopted the following routine injection schedule: 1000 to 2000 mg
initially depending upon age. The intramuscular route was used for children under age four
years. If the fever dropped in two hours, two more hours was allowed before the second
dose. After 24 hours, if the fever remained down, this same dose was given every six hours
for the next 48 hours. All sixty cases were well in 72 hours. Three however, had a
relapse, so the C was continued in all 60 cases for another two days every eight to twelve
hours.<br />
<br />
Home treatment was 2000 mg injected every six hours plus 1000 to 2000 mg orally every
two hours.<br />
Two of the 60 patients had throat muscle paralysis and needed oxygen and drainage but
were recovering in 36 hours.<br />
<br />
In a follow up article on “The Vitamin and Massage Treatment for Acute
Poliomyelitis” (Southern Medicine and Surgery, vol. 114, #8, August, 1952) he
summarized his years of treatment of this scourge that hit every summer. He felt much of
the fear about the disease was due to reckless propaganda. It is a dramatic disease mainly
affecting children. At that time the standard treatment was the splinting of the affected
muscles for two to eight weeks to prevent any kind of motion. Surgery was then used to
correct contractions and stabilize joints. At about that same time Sister Kenny was urging
the use of hot moist packs and early passive motion to relieve spasm. Dr. Klenner
used pillows to rest the affected muscles, immediate and continuous massage and passive
motion, and, of course, Vitamin C to kill the virus, reduce the swelling in the
brain, support the exhausted adrenals and rehabilitate damaged nerve tissue.<br />
<br />
Reducing spinal fluid pressure is important to allow nutrients to reach the shocked
nerve cells. The edema fluid “pressure in the central nervous system is the end
result of the inflammatory reaction caused by the virus.” it is probably augmented by
a deficiency of Vitamin B<sub>1</sub>. Early researchers tried to relieve this pressure by
the use of hypertonic sugar (10% dextrose) solutions designed to pull the fluid from the
brain, relieving the headache and allowing the circulation to open up sufficiently to
permit nutriments into the dying cells. It is known that virus infections deplete the
Vitamin C content of the adrenals. Chemical reactions follow resulting in high blood
sugar; “apparently the adrenal medulla is released from its inhibiting mechanism
allowing a concentration of free adrenaline in the blood high enough to cause
vasoconstriction.” Glucose would only serve to aggravate this artificial diabetes
(Maybe this is why some children develop diabetes after a virus infection, notably mumps).<br />
Vitamin C works as a destroyer of the virus but also as a safe and potent
dehydrator and diuretic. (Most patients complain of thirst after an I.V. of ascorbic
acid.) “Given in massive doses it will relieve the edema pressure of the cord and
brain, thus allowing normal amounts of B<sub>1</sub> to reach chemically shocked nerve
cells.” He occasionally used hypertonic sodium lactate as a dehydrator.<br />
Vitamin C is proven to be low in the blood and tissues of virus victims. In a
loading test, Heaslip found the urine of virus infected patients only revealed 20% of the
ingested dose compared to healthy controls who excreted 44% of the swallowed C.<br />
<br />
Jungeblut, a Vitamin C researcher, observed:
<br />
<br />
<ol>
<li>If a paralytic dose of polio virus were injected into the brains of monkeys, they all
developed paralytic polio. If, however, Vitamin C was injected along with the virus,
the animals remained free of the disease.</li>
<li>If monkeys were infected with a high dose of the virus, Vitamin C by injection
failed to modify the disease course.</li>
<li>If less virus were given and the Vitamin C was kept at 100 mg per day, the results
were variable. Dr. Klenner felt that the virus dose was not standard, and the
Vitamin C was too small and too infrequently given.</li>
</ol>
Dr. Klenner felt the best time to treat the virus was during the viremia stage;
that is, when it was floating about in the blood stream and had not invaded the tissues.
He repeats: “For optimum results the vitamin must be given in massive doses, every
two to four hours, around the clock.” Intestinal absorption is inconsistent; it must
be given by needle.<br />
<br />
Dr. Klenner wondered if some of the manifestation of polio might be due to mild
scurvy. Fever, vomiting, diarrhea, aches are all seen with scurvy and with polio.
Certainly when Vitamin C is given all these symptoms and signs disappear. Was it
scurvy or polio?<br />
<br />
He points out the similarities in pathology in the nerve cells of polio and beri-beri
(B<sub>1</sub> deficiency). He believed this sequence: the virus causes a Vitamin C
deficiency which stresses the medulla of the adrenal gland. Adrenaline is released, which
causes not only vascular constriction but affects carbohydrate metabolism, that is, it
causes the blood sugar to rise. B<sub>1</sub>, thiamin, is absolutely necessary for sugar
metabolism, and most diets are low in B1. In addition, absorption of vitamins and foods
are decreased when a disease is active. The Adrenaline-induced constriction of the blood
vessels about the intestines cuts some of the blood supply to the intestinal enzymes.
Pyruvic acid accumulates at the neuromuscular junction. To metabolize pyruvates, an
enzyme, cocarboxylase, is required. This enzyme has two B<sub>1</sub> molecules combined
with phosphate; no B<sub>1</sub>, no action. When pyruvates accumulate at this area,
fatigue is the result. The flaccid paralysis of polio is related. B<sub>1</sub> therapy is
indicated for polio and most cases of fatigue. “Nerve and muscle cells in a flaccid
extremity may be only tired, but it is reasonable to believe that unless they are relieved
promptly, they may die.” Massage would improve the circulation and help remove toxic
agents during this emergency.<br />
<br />
In 1956 Dr. Klenner published, “Poliomyelitis—Case Histories”
(Tri-State Medical Journal, Sept). He had a continuing supply of zingers he would throw at
doctors who insisted on disregarding his logic. He quotes Ratner, “There are two ways
of practicing the medical art: the first is to employ art; the second is to employ
fancy.” If one has used speculation, preconceived opinions and prejudice, then he is
proceeding by emotions, faith and dreams. We must proceed by REASON. Husky put it,
“Science commits suicide when it adopts a creed.”<br />
<br />
He was disturbed by the enthusiasm preached by the vaccine enthusiasts. They claim that
the dead Salk vaccine was safe and that it makes antibodies. He was convinced that was not
true. He argued for a live virus, which would be more likely to give the recipients
protective antibodies. 98% of all adults possess these antibodies. He seems to be arguing
for all of us to acquire a natural immunity to all viral infections by taking enough
Vitamin C to attenuate the disease no matter when it strikes.<br />
<br />
He suggests for poliomyelitis:
<br />
<br />
<ol>
<li>Gentle massage for paralysis, continuous in the first few hours.</li>
<li>Ascorbic acid, best intravenously, at 300 to 500 mg per kg of weight. In small children:
two to three grams intramuscularly every two to four hours. Ice on the injected muscle
will assuage the pain.</li>
<li>He suggests penicillin and sulfa drugs would be worthwhile, (I would disagree).</li>
<li>Desoxycortisone acetate is suggested daily x 3.</li>
<li>Thiamin, 100 to 250 mg a day for three months will help rehabilitate the nerves.</li>
<li>And make the patient EAT.</li>
</ol>
He reports some severely ill adults with polio. They had a high fever, 4+ headaches on
a scale of one to four, deep eye pain, stilt neck, muscle pain and spasm in the hamstring
muscles. Blood tests were negative for bacterial infection.<br />
<br />
Injections of twelve to twenty-two grams of Vitamin C were given every twelve
hours for six to eight times. The headaches and fever were improved in 48 hours, and most
were well in six to ten days at which time oral C was substituted: 1,500 mg or so at three
to four hour intervals. Then the B<sub>1</sub> for three months to heal the nerves.<br />
<br />
<hr />
<br />
<h3 align="center">
Hepatitis</h3>
Vitamin C will cure viral hepatitis in two to four days and allow the patient to
resume his usual activities. (500-700 mg/kg body weight taken orally; approximately 30
grams/24 hours in orange juice). Dr. Klenner reports that Dr. Bauer at the University
Clinic at Basel, Switzerland used just ten grams daily intravenously. It proved to be the
best treatment available. He indicated that hepatitis (infectious and serum) can be
reversed in a few days using intravenous Vitamin C. Heavy exercise had no effect on
the outcome. [Freebern]<br />
<br />
1) A 27 year old male with 103° temperature, nausea and jaundice of three days. 60
grams of sodium ascorbate in 600 cc of normal saline was given intravenously at 120
drops/minute. Five grams of Vitamin C was given orally every four hours around the
clock. Fifteen grams of C was again given three hours after the first I.V. Another 60
grams of C was given intravenously twelve hours after the initial one (he used 5% glucose
in water this time). That one took 75 minutes to accomplish. Then another fifteen grams of
C intravenously after two more hours.<br />
<br />
For the 30 hours of treatment he received 270 grams intravenously and 45 grams
orally—no diarrhea. Temperature was normal at this time and urine clear of bile.
Discharged from the hospital, he was back to work. C sets in as a flash oxidizer and helps
the body manufacture interferon, a natural antiviral agent.<br />
<br />
2) A 22 year old male with chills and fever and a diagnosis of viral hepatitis. His
roommate had been admitted the day before. Fifteen grams of sodium ascorbate was given
intravenously every twelve hours for three days, then once daily for six days. Sodium
ascorbate was swallowed at five grams every four hours (135 grams intravenously, and 180
grams orally). No diarrhea appeared with these doses. He was sent home on the sixth day
with no fever and no bile in the urine. Soon he was back to work. His roommate with just
bed rest was in the hospital for 26 days!<br />
<br />
3) Another male contracted hepatitis in Central America. There, he got lemon juice
orally and rectally. Hot mud packs were placed over his liver. He had 104° degree
temperature and was sent home. He was told to try bed rest and a protein diet. When
Dr. Klenner saw him, he was jaundiced, temperature = 101° and had a very large
tender liver. His I.V. was 30 grams sodium ascorbate and one gram calcium gluconate. Oral
C: five grams every four hours around the clock for three days. 400 mg adenosine IM.
100,000 units of palmitate Vitamin A given daily. On the fourth day he got 70 grams
ascorbate intravenously and one gram calcium. On the sixth day, he got another 70 grams
intravenously, and on the seventh day the bilirubin in the serum was down to 1.9 compared
to 98 on the first day; SGOT had fallen from 450 to 45. At home he took fifteen grams of C
orally, 1,400 mg of choline three times a day plus a high protein and carbohydrate
diet—no sequelae.<br />
<br />
4) A 42-year-old male suffering from chronic hepatitis had been unsuccessfully treated
with steroids for seven months. He was given B complex and Vitamin C: 45 grams of
sodium ascorbate plus one gram of calcium gluconate in 500 cc of water with 5% glucose was
given intravenously three times a week. He took five grams of C orally every four hours.
He was free of the disease in five months. Dr. Klenner felt if he had more massive
and continuous doses in the hospital he would have been well in a few weeks, but his peers
on the staff would have denied the patient this safe treatment.<br />
Dr. Klenner reemphasized the point, “Sodium ascorbate in amounts ranging up
to 900 mg per kilogram body weight every eight to twelve hours will effect cures in two to
four days.” Adenosine, 400 to 1,200 mg. intramuscularly, daily.<br />
<br />
He felt that the risk of serum hepatitis from dialysis machines could be eliminated by
flushing the machines with 50 grams of sodium ascorbate. When he needed to give a patient
a blood transfusion he always added ten grams of sodium ascorbate to each pint. The
Japanese, he said, have added but five grams of C to each unit of blood; result, no
hepatitis and in thousands of cases.<br />
<br />
<hr />
<br />
<h3 align="center">
Herpes Simplex & Zoster</h3>
Adenosine, 400 mg is given intramuscularly upon diagnosis. Fifteen grams of sodium
ascorbate intravenously is next using a six-cc syringe intravenously. Then a second dose
of adenosine, 400 mg, 30 minutes after the C. Paint the lesion with tincture of benzoin.
Then apply calomine lotion with 5% phenol. Continue to paint only the raw areas, but apply
the calomine and phenol to entire area. Continue the injections every twelve hours for
three days then daily for several days. A B complex capsule with 100 mg of each of the
B’s along with “massive” amounts of Vitamin A orally are taken daily.<br />
<br />
To control pain after the lesions heal, a daily I.V. is used containing thiamin, 1000
mg; pyridoxine, 300 mg; niacinamide, 600 mg, diluted to twenty cc with saline, daily for
five days. He uses twenty-three gauge, one inch needle.<br />
<br />
Herpes simplex must he treated as above for 72 hours as recurrences are common if
treatment is shortened.<br />
<br />
Fever blisters: three percent ointment of Vitamin C applied to the lips ten to
fifteen times a day in a water soluble base speeds up the cure. A three-percent solution
of ascorbic acid used as a douche will heal a cervical erosion; direct application of this
solution by the physician would be prudent. Twenty grams of C orally each day would
“erase this form of malignancy.” Dr. Klenner points out that the cancer
seems to hit those with a hereditary tendency; a virus grows more eagerly in the
susceptible. If there is a family tendency, oral C in large doses as a preventative makes
sense.<br />
<br />
<hr />
<br />
<h3 align="center">
Chicken Pox</h3>
Vitamin C orally is less reliable. Dr. Klenner noted his own daughter
struggling with chicken pox. She was getting 24 grams a day, but papules spread and the
itch was intense. After one gram of C intravenously, the itch stopped and she slept well
for eight hours. A new I.V. was then given and no new rash appeared. (Untreated chicken
pox victims break out for five full days). He noted this ability of C to terminate the
usual progress of virus diseases.<br />
<br />
One to three injections of 400 mg per kg every eight hours will dry up chicken pox in
24 hours. Controls nausea with one gram of C per five cc of fluid. Thirst is precluded if
a glass of juice is drunk just before the I.V.<br />
<br />
<hr />
<br />
<h3 align="center">
Hard Measles</h3>
He reports some cases:<br />
<br />
1. A ten month old baby had the high fever, watery nose, dry cough, the red eyes, and
the Koplik spots that gave the disease away: hard measles. He gave 1000 mg of C every four
hours. After twelve hours the temperature had fallen to 97.5°; the cough had stopped and
the redness of the membranes had cleared. Just to see if this improvement happened to be
the natural course of the disease, he stopped the C for just eight hours. The fever rose
to 103.4°. The C injections were resumed and the fever dropped in a few hours to 99°.
1000 mg was given every four hours; no rash developed.<br />
II. An eight-year-old developed measles and mumps closely followed by encephalitis
(T-104°). He could not eat, was stuporous and responded only to pain. Two hours after one
injection of 2000 mg of Vitamin C, he sat up, ate a hearty meal and then played. In
six hours he started to revert to his previous stupor, and the fever returned. Twelve
hours after a second injection of two grams, and 1000 mg every two hours by mouth, he
recovered. Dr. Klenner said, “The rude irritability shown prior to the first
injection of Vitamin C was strikingly absent.” I think what he wants the reader
to grasp is that the symptoms of these devastating virus diseases are similar to the clues
seen in scorbutic patients.<br />
<br />
The bloody nose is common in measles, but can be relieved with one or two injections of
Vitamin C (one to four grams depending on individual differences). Bleeding
tendencies are common with scurvy. Did the disease allow the scurvy to become manifest?
These symptoms are due to acute Vitamin C loss and are nature’s way to ask for
help.<br />
<br />
<hr />
<br />
<h3 align="center">
Mumps</h3>
He reports cases of influenza, encephalitis, and measles easily cured with
Vitamin C injections and oral doses. A 23-year-old male developed mumps plus
bilateral orchitis; his fever was 105°, and he was in overwhelming pain with
“testicles the size of tennis balls.” After one 1000-mg injection of
Vitamin C intravenously the pain began to subside and after six more shots spaced
every two hours the pain was gone. The fever was normal in 36 hours. He was up, about and
well in 60 hours. Total dose 25,000 mg.<br />
<br />
<hr />
<br />
<h3 align="center">
Mononucleosis</h3>
Dr. Klenner felt mono is related to cancer because the same virus (Epstein-Barr)
is found in Burkett’s lymphoma. The disease, mono, can be eliminated with an I.V. of
C in just a few days, “The actual time being directly proportional to the amount of
the vitamin employed in relation to the severity of the infection.” (Most of us use
Dr. Cathcart’s formula for the amount of C to be given: “I think this is a 50
gram disease: some fever, generalized aches, but ambulatory.”) In one patient who was
given the last rites by her church, the girl’s mother took things into her own hands
when the attending physician refused to give ascorbic acid. In each bottle of I.V. fluid
she would secretly and quickly “tap in” 20 -30 grams of Vitamin C. The
patient made an uneventful recovery. Her mother has her BS in nursing and has been a long
time advocate of massive “C” therapy. (100 gram disease: 102-103°, holding down
fluids but needs to stay in bed, miserable. 200 gram disease: 104 degree temperature,
semi-comatose, somewhat dehydrated; hospitalization a good idea.)<br />
<br />
The theory behind the use of adenosine: ascorbic acid stimulates an enzyme which breaks
down the nucleic acid in the virus. Some individuals cannot manufacture enough adenosine
to aid this enzyme activity. Purines are catabolized and are thus unavailable for the
production of new viral nucleic acid.<br />
<br />
<hr />
<br />
<h3 align="center">
Other Diseases</h3>
Dr. Klenner tells the reader about curing <b>diphtheria</b> with Vitamin C
intravenously or intramuscularly. Bacillary dysentery is stopped in 48 hours with
injections of C.<br />
<br />
<b>Pancreatitis</b>. He treated but one case of this. He put 60 grams of sodium
ascorbate in 1000 cc of 5% dextrose in water and let it drip in rapidly and the patient
was able to go home in twelve hours.<br />
Cardiovascular diseases, hypermenorrhea, peptic and duodenal ulcers, postoperative and
radiation sickness, rheumatic fever, scarlet fever, poliomyelitis, acute and chronic
pancreatitis, tularemia, whooping cough, and tuberculosis.<br />
<br />
In one case of <b>scarlet fever</b>, antibiotics had no effect, but the fever responded
dramatically when 50 grams of C was given intravenously.<br />
<br />
Others - Massive doses for <b>rheumatic fever</b>. C will cure TB by removal of the
organism’s coat. Also pneumonia—(so it does not matter if one has a viral or
bacterial pneumonia, it works).<br />
<br />
<b>Rocky Mountain Spotted Fever</b>. Dr. Klenner was an authority in the treatment
of this rather debilitating, serious disease because his practice was right in the middle
of a constant locus of infection for tick bite fever.<br />
<br />
Dr. Klenner had been taught in his training that there was no cure for it, only
supportive. So when he was confronted with an obvious case—104.4° degree
temperature, spots over body, coma, and positive blood test—he quickly gave 30 grams
of C intravenously every six hours. The patient was given para-aminobenzoic acid orally,
six grams, every two hours x3, then 4 grams every two hours for 24 hours, then 4 grams
every 4 hours until his fever was gone for 24 hours. At about the sixth hour of treatment
he became conscious and rational. He was sent home on the sixth day, fully recovered.<br />
<br />
He reported the story of a twelve-year-old female with spots and 105° temperature. She
was given chloroamphenicol and PABA but with only a poor response on the third day, so she
was given an I.V. with 30 grams of C. In two hours she was almost well, cheerful and
responsive. She was given 30 grams every eight hours and was well and home in seven days.<br />
<br />
He wrote of his son, sick with R.M.S.F. who almost died. He needed Vitamin C,
vibramycin (an antibiotic), PABA. Thiamin 1000 mg, B2 300 mg, and B3 500 mg were added to
the I.V.’s daily. On the third day his temperature was still up (105 degrees); he was
losing interest, and candida was developing. He finally got well on the fourth day.<br />
<br />
What Dr. Klenner shows and tells us that with a devastating disease like R.M.S.F.;
everything known to be helpful should be used. It seems obvious that antibiotics have a
place, but Vitamin C is extremely useful. He pointed out one medical center used the
large doses of PABA, and had no fatalities, except a six year old who was given only one
half the calculated dose.<br />
<br />
The C is given around the clock and at the 500-900 mg per kg body weight level. The
disease “can always be reversed.”<br />
<br />
Dr. Klenner even treated <b>trichinosis</b>. In the Tri-State Medical Journal for
April, 1954, an article entitled, “The Treatment with Massive Doses of Vitamin C
and Para-Amino-Benzoic Acid” Dr. Klenner pointed out that sixteen percent of
humans in the U.S. have these worms. An acute case will have puffy eyelids, high
eosinophil count in the blood stream, pain and swelling of the muscles, fever, profuse
sweating, cough and profound weakness. The eosinophil count is high with some allergies
also. He found that the lymphocytes stimulate anti-body formation and that the lymphocytes
rise with the patient’s recovery.<br />
<br />
He reported the case of a man who had eaten sausage. He came down with a fever (104°),
very puffy skin of the eyelids, hacking cough. Tests were positive for trichinosis and the
eosinophil count was fifteen percent (normal less than four percent).<br />
<br />
He was given large doses of C by needle because it would aid antibody formation and to
detoxify him. Calcium gluconate, one gram every day for several days. Antibiotics were
worthless.<br />
<br />
Fever rose to 106°, and he lapsed into a semi-coma. As it reminded Dr. Klenner of
tick bite fever, he forced para-aminobenzoic acid down his throat. Four grams initially,
then 3 grams every 2 hours. Eight hours after this was started he ate a full
breakfast—the first in several days. His profuse sweating stopped. His temperature
returned to normal. The PABA was stopped after two days to see the effect; in 36 hours the
fever was back up to 101°. The sweating recurred.<br />
<br />
The PABA was restarted at three grams every 2 hours during the day and every three
hours at night. After 9 days he was well, the PABA was stopped and there was no
recurrence.<br />
<br />
Another patient, a woman, age 33, had a fever (103.4°), swollen lids, eosinophils 30%,
cough. She took 6 grams of PABA and then 3 grams every three hours for 37 hours then that
amount every 4 hours. Fruit juice also. Twelve grams of C was given every twelve hours.
Ten grams of C orally daily. She returned to work in eight days.<br />
<br />
Dr Klenner had no explanation as to why PABA was a curative for trichinosis.<br />
<br />
<b>Tetanus</b> (Lockjaw). In two articles in the Tri-State Medical Journal for June and
July of 1954, he again scored some points for Vitamin C in “The History of
Lockjaw”, and “Recent Discoveries in the Treatment of Lockjaw.”<br />
<br />
He stated that lockjaw is not difficult to cure. He believed that doctors rely on
antitoxin as the sole therapy because some “authority” recommends it. Many
patients are sedated “to the point of narcosis.”<br />
<br />
He felt that the practice of injecting the tetanus antitoxin into the tissues near the
wound was for medico-legal reasons as it had no benefit and might even be harmful. The
antitoxin “cannot travel from the circulation into the nervous system and unless it
be injected into the nervous tissue, it is relatively valueless.”<br />
<br />
Dr. Klenner reports on other research: Vitamin C inactivates the toxin of
tetanus.<br />
<br />
He recounted the history of a six-year-old boy who had never had any immunizations and
developed tetanus after falling off his pony into some brush. Over a period of three weeks
the boy developed increasing muscle tightness, abdominal cramps, inability to smile or
open his mouth. Liquids were all he could manage. If stimulated his back would arch so his
body was as a bridge resting on heels and back of head.<br />
<br />
Dr. Klenner used Tolserol to control the convulsive spasm without sedating the
senses unduly (the FDA has taken it off the market; Methocarbamol can be used
intravenously with comparable results). The boy was treated with Vitamin C,
penicillin, tetanus antitoxin and Tolserol. He spent eighteen (18) days in the hospital,
but the use of tetanus antitoxin seemed to aggravate the seizures and required more
Vitamin C, sedatives and its use definitely prolonged the hospitalization.<br />
<br />
He received 2 to 4 grams of Vitamin C every four to six hours depending upon the
symptoms and within one hour he would be calm and free of spasms. The idea was to help the
body’s natural detoxifying process. He also developed hives from the TAT or the
penicillin and needed Benadryl and Adrenaline for that.<br />
<br />
He summarized <b>the treatment of tetanus</b>:
<br />
<br />
<ol>
<li>debride and clean any wound thoroughly. (He felt ether was good because it kills most
bacteria without destroying tissue.)</li>
<li>75,000 units antitoxin deep intramuscularly above the wound,</li>
<li>intravenous fluids,</li>
<li>massive doses of Vitamin C intravenously around the clock,</li>
<li>intradermal tetanus toxoid, 0.1 cc for five consecutive days,</li>
<li>intravenous Tolserol—now Methocarbamol. He felt all states should pass legislation
requiring tetanus toxoid for all ages.</li>
</ol>
He felt that the number of fatalities from the disease were equal to the number of
those who die from the treatment. He emphasized some principles of treatment 30 to 40
years ago that many of us have forgotten: namely, do no harm, and the body has tremendous
restorative powers if the doctor will supply it with the raw materials to promote
recovery.<br />
<br />
<b>Urethritis</b>: Dr. Klenner points to the study done by Rous in 1971. Only
three grams of Vitamin C per day stopped the pain and frequency of urination in just
four days. Apparently alkaline urine allows phosphate crystals to form; Vitamin C
acidified the urine and the crystals went back into solution.<br />
Chronic <b>cystitis</b> is usually associated with alkaline urine. Germs grow more
easily in this alkaline urine. Vitamin C will discourage these bacteria and cut the
chance of an ascending infection which might devastate the kidneys (pyelitis). Ten grams
of C per day are suggested.<br />
<br />
<hr />
<br />
<h3 align="center">
Other Conditions</h3>
<b>Antabuse</b> is a chemical used to discourage alcoholics from drinking. Alcohol and
Antabuse in the body form acetaldehyde; the person feels awful; weak, headaches even coma
as this case illustrates. Dr. Klenner felt he may have been the first to recommend
Vitamin C in the control of this chemical reaction. The man was on Antabuse. At one
Christmas holiday his “friends” persuaded him to drink with them. Shortly
thereafter he was brought to the emergency room where Dr. Klenner happened to be. He
was unconscious with BP of 90/60. He suffered from shock (same clinical picture with
barbiturate poisoning.) His I.V. was 500 ml of 10% glucose in water with 50 grams of
sodium ascorbate. After 30 grams had run in, he awakened, felt well and wanted to go home.
He got the whole 50 grams in three hours and was sent home. He also received oxygen by
nasal mask.<br />
The company that manufactures Antabuse suggests but one gram intravenously as an
antidote calling it “massive.” Dr. Klenner felt that amount was
“without value.”<br />
<br />
For acute alcoholism Dr. Klenner has given 1000 mg of thiamin intramuscularly
every two hours until recovery. Pyridoxine, 500 mg is given every six hours. 40 grams of C
intravenously will detoxify the patient.<br />
<br />
<b>Arthritis</b>: Vitamin C counteracts the damaging effects of aspirin. C is the
number one precursor for collagen formation. If serum levels of C are high, synovial fluid
is thinner allowing for easier joint movement. Those taking 15 to 25 grams daily will
experience commensurate benefit. Prevention seems prudent. “A person who will take
ten to twenty grams of ascorbic acid a day along with other nutrients might very well
never develop arthritis.”<br />
<br />
<b>Cancer</b>: He cites Schlegel’s (Tulane University) use of ascorbic acid (1.5
grams a day only) in preventing bladder cancer recurrence. “This is the so called
wasted Vitamin C.”<br />
He “demonstrated that in the presence of ascorbic acid, carcinogenic metabolites
will not develop in the urine. They suggested that spontaneous tumor formation is the
result of faulty tryptophan metabolism while urine is retained in the bladder.” Other
researchers report that the depletion of mast cells from guinea pig skin was due to
ascorbic acid deficiency. It suggests Vitamin C is necessary for the formation and
maintenance of mast cells.<br />
<br />
Vitamin C will control myelocytic leukemia with 25-30 grams orally daily.
“How long must we wait for someone to start continuous ascorbic acid drip for two to
three months, giving 100 to 300 grams each day, for various malignant conditions?<br />
<br />
Small basal cell epithelioma: 30% Vitamin C ointment.<br />
<br />
He cites a disturbing study: particles resembling viruses were found in some breast
milk samples of women with breast cancer. Could this help to explain why some cancers seem
to be “inherited?” It makes sense that all members of cancer prone families
should be taking at least ten grams of C daily.<br />
His protocol for treating cancer is printed here in total, although I do not understand
the rationale for some of the ingredients. All of this is designed to kill the cancer
cells by shoring up the immune system. He even recognized the therapeutic value for a
positive attitude.
<br />
<br />
<ol>
<li>Use radioactive cobalt when and where indicated.</li>
<li>Give 45 grams of sodium ascorbate intravenously every twelve hours for one month. Then
use 60 to 65 grams in 500 cc of normal saline or 5% dextrose in water for five days a week
until a cure is obtained. It usually takes five months.</li>
<li>Each bottle is to contain one gram of calcium gluconate, a cc of some B complex, plus
1,200 mg of thiamin, 300 mg of pyridoxine, and 600 mg of niacinamide.</li>
<li>Oral sodium ascorbate, 5, 10, 20, grams daily. The dose depends upon the bowel
tolerance.</li>
<li>Vitamin A palmitate, 50,000 units, daily, orally.</li>
<li>Pantothenic acid, (B5) one gram orally four times a day.</li>
<li>Amino acid protein powder with all the eighteen amino acids. 60 tablets each day or, if
a powder, several tablespoons daily. This supports the immune system and the enzymes.
Tyrosine should be taken separately, if possible, as this one makes the others work
better; 500 mg tablets—six daily.</li>
<li>In addition, a high protein diet using white chicken meat, fresh fish, chicken livers,
and brown-shelled eggs. Beef (but once a week) should be as lean as possible: lean stew
beef or sirloin tip are the best but have the butcher grind it three times. Hamburgers?
Only once a week. No sugar and no starches. Fruit and fruit juices are permitted. Almonds
are excellent.</li>
<li>30 to 40 apricot almonds should be chewed every day in divided doses until a continuous
bitter almond taste develops. At this point the patient cuts the dose in half. “This
will form cyanide by way of the stomach acid. Cyanide will kill cancer cells.
Vitamin C will protect one against the lethal effects of cyanide. It is the antidote.
500 mg tablets of vitamin B<sub>17</sub> are available. One after each meal and at bed
time.” (Not everyone would agree with this part of the therapy. Cancer victims are
still getting amygdalin B<sub>17</sub>, as injections from Mexico, but there is some doubt
as to its efficacy. LHS)</li>
<li>Vitamin E, d-alpha tocopheryl acetate, 400 International unit size, 3,200 units daily.
Don’t take iron with it.</li>
<li>One pint of grape juice daily.</li>
<li>B complex tablets with 100 mg of each of the B’s and 100 mcg of B<sub>12</sub>. Six
to eight tablets daily. Theragran-M or a similar capsule with all the minerals to replace
what is being pulled out by the C.</li>
<li>Maintain the hemoglobin at 13 grams.</li>
<li>Keep a good attitude.</li>
</ol>
He reported a case of a man with lymph glands all over his body. He got the above
treatment and although the glands increased in size for a while, his liver and spleen were
back to normal size in four months. Dr. Klenner noticed a ‘parachute-like’
substance in the urine. Microscopic examination revealed they were clumps of cancer cells.<br />
<br />
Another case was that of a woman who had an adenocarcinoma of two years duration. She
had had chemotherapy, two surgeries and extensive radiation over her chest, especially the
neck area where the cancerous glands were. The cancer had spread to her lungs, her abdomen
and six glands in her neck. Dr. Klenner gave her the above protocol. In three months
the lesion in her lung had cleared and gone were the glands in her neck. After six months
of intravenous Vitamin C and the B complex, the abdominal masses had disappeared, but
she could not swallow food. The radiation had scarred her esophagus beyond dilatation and
she refused more surgery. The cancer was gone; she died from starvation due to the
radiation.<br />
<br />
Dr Klenner summarized this paper with this: “The results suggest that larger daily
amounts could be given in a hospital with faster results. I would suggest at least 100
grams in 1000 cc of fluid and given every twelve to 24 hours. The vitamins and the calcium
gluconate also must be given.” He thought interferon could be assayed while the
patient is in the hospital. “How long will it take for the general population to
challenge the drug cartel?”<br />
<br />
There is a relationship of Vitamin C and <b>cholesterol</b>. Scorbutic guinea pigs
have high cholesterol levels. Way back in 1947 high intravenous doses of Vitamin C
were found effective in lowering cholesterol levels. One researcher [Spittle, 1971,
Lancet] postulated that arteriosclerosis might be the end result of a long term deficiency
or negative balance of Vitamin C. [Hecker] He and Dr. Klenner saw the
cholesterol levels in the blood of subjects vary with the amount of C used. In one patient
the cholesterol was lowered 42 mg percent in six weeks when his oral intake of
Vitamin C was increased from 10 grams a day to 20 grams a day.<br />
<br />
This all makes sense as “the main pathway of cholesterol catabolism is in
conversion to bile salts.” Vitamin C aids in the enzymatic conversion. Guinea
pigs, who like humans cannot manufacture their own Vitamin C, will use up dietary
Vitamin C if fed a high cholesterol diet. “Guinea Pigs fed a diet free of
ascorbic acid showed a 600% acceleration in cholesterol formation in the adrenal
glands.” The Soviets have published many articles demonstrating these effects. This
might explain why colds and virus flu are more common in the winter because fresh fruits
and vegetables are less available and fat in the diet in the winter might use up
Vitamin C faster. Gallstones can be made to develop in guinea pigs when fed a diet
rich in cholesterol and low in C.<br />
<br />
(In Medical School we were given the mnemonic to aid in the diagnosis of the gall stone
victims: “Fair, fat, and forty.” Susceptibility plus dietary factors; it makes a
lot of sense.)<br />
<br />
Dr. Klenner quotes the literature as to the use of Vitamin C in coronary
artery disease in animals as well as humans. Arteriosclerosis develops in guinea pigs when
fed a high cholesterol diet but develops rapidly in scorbutic animals even without
exogenous cholesterol. Extra C was able to absorb the plaques. The diet is important, but
extra C seems to be critical especially in those with a family tendency.<br />
<br />
“We must protect our hearts from stress. Adequate Vitamin C is one
answer.” Where did Linus Pauling learn about his need for large doses? Probably from
Dr. Klenner. “Mortality rate for middle-aged people dropped significantly with
increased doses of Vitamin C” [Dr. Klenner was quoting J. Stamler from <i>Comprehensive
Treatment of Essential Hypertensive Diseases</i>. Monograph on Hypertension, Merck, Sharp
and Dohme.] Pauling currently takes 18 grams a day. He seems to be doing well at the age
of 86 years (July, 1987). [Dr. Pauling lived to 93 years –ed.]<br />
<br />
<b>Cavities</b>: A gram of Vitamin C every day for each year of life (five grams a
day for the five year old) will prevent cavities. Ten grams a day from age ten years for a
lifetime should maintain that advantage.<br />
<br />
He quotes Shaw who felt that deposits on the teeth represent a pre-scurvy condition and
that those so afflicted should be taking 2000 mg a day of C before some nasty virus
strikes.<br />
<br />
<b>Disc, ruptured</b> intervertebral: will be prevented with the ten-grams-a-day dose.
Adequate amounts seem necessary for disc metabolism and maintenance.<br />
<br />
<b>Corneal ulcers</b>: healed with but 1.5 grams of C daily. The pain of a corneal burn
was relieved immediately with twelve grams of C intravenously. The cornea was normal in 24
hours. [Boyd & Campbell]<br />
<br />
<b>Diabetes</b>: He noted back in 1951 that the urine in his patients showed a reducing
substance; severe virus infections will allow sugar to spill into the urine.
Vitamin C acts as a reducing agent and it would appear that diabetes has been
induced.<br />
<br />
He reported the story of a seven year old diabetic, who developed measles, and his
insulin requirements went from 5 units to more than 90 units a day, but with one gram of
Vitamin C every four hours his infection and elevated blood sugar came under control.
In these diabetic cases, the Vitamin C can be cut back to reasonable levels after the
infection is under control. Large prolonged doses of “Vitamin C might prove
undesirable due to its dehydrating and diuretic powers.”<br />
<br />
He feels that the pathological condition in this case means that adrenaline was
flooding the boy’s system. The regulator of the adrenaline mechanism had been removed
so the constant supply caused a prolonged vascular constriction. This action on the blood
vessels creates asphyxia of the tissues leading to acidosis. This acidity leads to
adrenaline hyperglycemia. “Slight blood sugar elevation can be controlled with sodium
bicarbonate. This vascular constriction is operative in the pancreas and could restrict
the production of insulin and pancreatic enzymes.”<br />
<br />
As a matter of fact Dr. Klenner had been studying the effects of ten grams of C
per day orally in patients with diabetes mellitus; 60% were able to control the condition
with diet and C. The other 40% were able to reduce the insulin dose. Wounds healed more
readily. The C assists the liver in its function of carbohydrate metabolism.<br />
<br />
<b>Glaucoma</b>: Dr. Klenner was disturbed that marijuana was being used for the
reduction of intraocular pressure. ”One would need to be a chain smoker to maintain
worthwhile levels.“ He quotes Bietti who used large C doses; Virno’s patients
use 35 grams of C (100 mg/kg after meals and bedtime) in divided doses during the 24 hours
and this osmotic dehydration of the eyeball was safe and effective. “The size of the
dose does make a difference—a real difference.”<br />
<br />
Dr. Klenner has found in his investigation of over 300 <b>pregnancies</b>, that
the stress of the condition pushed the needs for C in women up to 15 grams a day. The
human fetus is a parasite draining available C from the mother. We are all different and
our needs for Vitamin C vary depending upon heredity, environment, stress—or its
perception. He reminds us of Roger Williams’ research in 1968 showing that some
guinea pigs needed twenty times more Vitamin C than others to maintain their health.
(The usual dose for pregnant humans: 4 grams daily in the first trimester; 6 grams daily
in the second trimester; 8 to 10 grams in the third trimester). He obtained excellent
results with these large doses of C in women who had been habitual aborters. [Greenblatt]
One woman had had five miscarriages and then with the Vitamin C went on to have two
normal pregnancies. The German literature is full of cases of these good results.
Hemoglobin was easier to maintain, leg cramps were less (Vitamin C enhances iron and
calcium and magnesium absorption). Striae gravidarum (<b>stretch marks</b>) were
seldom encountered. Labor was shorter and less painful. No post partum hemorrhage. The
perineum was more elastic and if Vitamin C was maintained, it continued to remain
firm.<br />
Infants are robust with this Vitamin C. None required resuscitation. 50 mg of
ascorbic acid was begun on the infant’s second day and was gradually increased as
time went on. A set of quadruplets in this series were healthy and taking milk on the
second day. It is especially helpful for the rapidly growing connective tissue, teeth and
blood vessels. [King]<br />
<br />
<b>Schizophrenia</b>: Dr. Klenner reminds us of Hoffer and Osmond’s work with
niacin and Vitamin C back in the early 1950’s. Six to 8 grams of C a day made
the niacin work. One schizophrenic took one gram every hour for 48 hours and was
completely recovered for six months with no further treatment. These megadoses halved the
suicide rate. It has been demonstrated that schizophrenics burn up C ten times faster than
the normal population. Most people show some spill of C in the urine at 4 grams per day;
schizophrenics have to take ten times this amount before it can be detected.
Dr. Klenner noticed this spillage in patients severely affected with a virus only
after two to three days of large doses of C and improvement had begun. (Could
schizophrenia be due to a virus?)<br />
<br />
<b>Burns</b>: can be treated with Vitamin C. “30-100 grams of Vitamin C is
the proper amount to employ.” (500 mg per kg of body weight diluted to at least 18 cc
per gram of C using 5% dextrose or saline in water or Ringer’s solution, repeated
every eight hours for several days, then at twelve hour intervals. Calcium gluconate is
added.) “Vitamin C is given until healing takes place.” It takes seven to
thirty days depending upon the degree of the burn. It may prevent the need for grafting as
it keeps the tissues oxygenated thus preventing the blood from sludging. [Kniseley] On the
fourth to fifth day the malodorous burn eschars will fall off leaving normal tissue.
Vitamin C also eliminates pain; opiates are less necessary. (It stimulates endorphin
production in the brain.)<br />
<br />
In an article he published in the <i>ICAN Journal</i> (there is no date, but it
was probably published in 1973 or 74) he states that Vitamin C is truly a miracle
substance. He believed that large doses of intravenous Vitamin C early in the
post-burn phase would eliminate the third degree burn with its infection and scarring.
Blood sludging seems to be the basic villain that leads to rigid masses of eschar.
[Berkeley] Oxygen is cut off. Tissue destruction is added to already burn-damaged skin.
Vitamin C levels in the blood and urine drop. [Lund & Levenson; Lam]
Vitamin C is necessary for granulation tissue and skin formation. [Bergman] Three
percent ascorbic acid solution is used as a spray every two to four hours for five days.
[Klasson]<br />
<br />
Pseudomonas: (a nasty bacteria, often seen in burn patients; very resistant to
antibiotics): three percent spray plus massive injections.<br />
<br />
<b>Heat stroke</b>: 500 mg per kg of body weight will reverse it.<br />
<br />
<b>Sunburn</b>: One gram taken every one to two hours during exposure will prevent
sunburn; an I.V. injection will quickly relieve the pain and erythema. Even second-degree
burns will be healed.<br />
<br />
<b>Prickly heat, heat stroke, heat collapse</b> can all be treated; the latter needs
twelve to forty grams intravenously. Electric shock patients must be given Vitamin C
immediately after the accident—including lightning victims.<br />
<br />
Vitamin C will control the side effects of <b>radiation</b> including radiation
burns. “Who can say what 100 to 300 grams given intravenously daily for several
months might accomplish in cancer? The potential is so great and the employment so
elementary that only the illiterate will continue to deny its use.”<br />
<br />
Vitamin C inhibits the deaminizing enzymes from the damaged cells (due to burns,
injury, infections). Histamine is produced by these enzymes. The shock is controlled.
[Chambers & Pollock; Clark & Rossiter]<br />
<br />
<b>Surgery</b>: Way back in 1960 and again in 1966, Dr. Klenner delivered papers
before the Tri-State Medical Society calling attention to the “scurvy levels” of
C in post-operative patients. The levels began to fall six hours after surgery and by 24
hours the levels were 3/4 lower than pre-op. Tensile strength of healing wounds is lowered
if the plasma drops to scurvy levels. The lower the C levels the poorer the wound heals.
[Bartlett, Lanman) Even as little a dose as 500 mg of C orally “was remarkable
successful in preventing shock and weakness,” following dental extraction, he quotes
Schumacher.<br />
<br />
He remembers a surgery case in 1949 when he assisted a surgeon in a potentially
hopeless case. Extensive adhesions of the viscera defied separation. The surgeon repaired
twenty tears and closed the abdomen. She should not have survived. The patient was given
two grams of C every two hours intravenously for 48 hours and then four grams per day. In
a day and a half she was up walking and in a week discharged home with normal bowels and
no pain.<br />
<br />
30 grams should be given intravenously daily—post-operatively, until food and
pills are tolerated orally.<br />
<br />
Dr. Klenner used 10 grams preoperatively intravenously and ten grams in each
post-operative bottle and then ten grams orally when eating was resumed. Surgical wounds
rarely separated with this method. Fractures healed faster. (Some surgeons will give ten
grams of Vitamin C at the end of the operation, and the patient is awake and alert in
60 seconds. No need for the nausea and vomiting in the recovery room.)<br />
<br />
<hr />
<br />
<h3 align="center">
Toxins & Heavy Metals</h3>
<b>Heavy Metal Poisoning</b>s: Especially lead and mercury—are controlled with
Vitamin C injections and oral intake. An intake of Vitamin C daily will protect
animals—and by extrapolation, humans—from fatal doses of mercury. If a guinea
pig needed 200 mg one day to protect it from an otherwise fatal dose of mercury, the human
would need 14 grams daily. Smaller doses would be able to protect the body from smaller
amounts of the toxin.<br />
<br />
<b>Lead poisoning</b>: 350 mg of Vitamin C per one kg of body weight taken
intramuscularly every two to four hours; recovery in less than 72 hours.<br />
<br />
Dr. Klenner found that the amount of C used “in any case is the all important
factor. In 28 years of research we have observed that 30 grams each day is critical in
terms of response” regardless of age and weight. (Barbiturate intoxication, snake
bite and viral encephalitis may require larger doses in some individuals.)<br />
<br />
<b>Carbon monoxide</b> (CO): poisoning is on the rise due to smoking and city living.
CO interferes with oxygenation of tissues as it ties up hemoglobin. (The affinity of CO
for hemoglobin is 300 times that of oxygen.) It would be especially dangerous in hearts
already compromised by diseased coronary vessels; those vessels cannot dilate in times of
extra need, e.g., CO poisoning. Smokers, and by inference, anyone exposed to CO or
pollution should be taking extra Vitamin C. He points to the report [Pelletier] that
shows when smokers quit, their “ascorbic level approaches that of the
non-smoker.” In acute CO poisoning: if 12 to 50 grams of Vitamin C is injected
rapidly into the blood stream, it acts as an oxidizer and will “pull CO from
hemoglobin to form carbon dioxide” which is easily exhaled. A burn victim should
immediately receive a dose of 500 mg of C per kg of body weight intravenously. It will
“neutralize the CO or smoke poisoning while at the same time it will prevent blood
sludging which in the major factor in the development of third degree burns.”<br />
An accidental carbon monoxide poisoning was reversed in ten minutes with 12 grams of
ascorbic acid in a 50 cc syringe using a twenty gauge needle. (”We employ a
twenty-gauge needle when using a 50 cc syringe; a twenty-one gauge for a thirty-cc
syringe, a twenty-two gauge for a twenty cc syringe and a twenty-three gauge needle for a
ten cc syringe“).<br />
<br />
Two boys were sprayed with <b>pesticide</b>, one received Vitamin C (10 grams)
every eight hours and went home on the second day. The other boy only fluids; his skin
showed a bad chemical burn; he died on the fifth day.<br />
<br />
Vitamin C will reverse the <b>shock and low blood pressure from barbiturates</b>,
muscarine, and formic acid. One suicidal patient ingested 2640 mg of barbiturate. Twelve
grams was administered using a 50 cc syringe. In ten minutes the blood pressure rose from
60/0 to 100/60. 100 grams was given in the vein for three hours at which time the patient
was awake. The use of large doses of C should be routine in these cases of chemical shock.
“The needle used to give a syringeful of C was attached to a bottle of 5% dextrose in
water with 50 grams of ascorbic acid. She received 125 grams of C. C not only assists with
hepatic metabolism but also as a major diuretic, flushing these compounds out by way of
the kidneys. Oxygen by nasal tube ran constantly.”<br />
<br />
Another patient had taken 2400 mg of Seconal plus para-aldehyde. She was awake after 42
grams of C was administered. The C was injected as fast as a twenty-gauge needle could
carry the flow. Consequent doses of 75 grams intravenously and thirty grams of C taken
orally over a period of 24 hours saved her life.<br />
<br />
<hr />
<br />
<h3 align="center">
Bites, Toxins, Allergies</h3>
In another Tri-State Medical Journal of December, 1957, he outlined the physiology and
treatment of <b>Black Widow Spider poisoning</b> in a case history. Some of those bitten
are not affected at all because the spider was out of poison, but some can be devastated
and may die, partly because of poor resistance but also due to the quantity injected.<br />
<br />
It can be confused with pancreatitis, renal colic, food poisoning, tetanus, angina,
bowel obstruction, pneumonia, perforated ulcer. The abdominal wall muscles become rigid,
the victims have cold sweat, their temperature and blood pressure shoot up, they vomit,
have muscle twitches and spasms, cyanosis, chills, convulsions and delirium. The painful
muscle spasms occur within minutes of the original bite. The cramps occur in all the large
muscles of the body; the victims roll and toss and moan in agony.<br />
<br />
Until someone used calcium gluconate, there were 90 ineffective treatments. An
anti-venom is on the market, but severe reactions and even death have been attributed to
its use.<br />
<br />
The treatment Dr. Klenner suggests is his friend, Vitamin C, 350 mg per kg of
body weight intravenously along with calcium gluconate.<br />
<br />
His three and a half year old patient had been getting worse for 24 hours with
abdominal cramps which the parents assumed were due to food poisoning. She became quieter,
feverish, constipated and her abdomen was exquisitely tender. She was becoming stuporous.<br />
<br />
Dr Klenner noted the red, swollen area around her naval, and two tiny spots about one
eighth of an inch apart were noted in the middle: the fang marks of a Black Widow Spider.
He gave one gram of calcium gluconate and 4 grams of Vitamin C intravenously. In 6
hours she was more responsive, and her temperature had dropped from 103 degrees to 101
degrees and she was given another four grams I.V.<br />
<br />
In another six hours, her temperature was but 100 degrees, and she could swallow
fluids. The next day she was active, and 50% of the discoloration had disappeared. She
received another 4 grams of C intravenously and 3 grams intramuscularly. At home she
swallowed one gram of C every three to four hours. An enema produced a bloody return. When
she recovered, she remembered brushing “a big black bug off her stomach,” before
she took ill.<br />
<br />
Dr. Klenner had treated eight cases of Black Widow Spider bites. “It is
criminal to give these patients an opiate to relieve their pain, for in so doing you might
add to their distress and actually precipitate a fatality.”<br />
<br />
“Some ascorbic acid behaves much like calcium in the body, and also acts
synergistically with it, we elected to observe its action.” The child was destined to
die. “Some physicians would stand by and see their patient die rather than use
ascorbic acid because in their finite minds it exists only as a vitamin.”<br />
<br />
Dr. Klenner was very confident about the benefits of intravenous Vitamin C to
treat the poisonous effects of insects and reptiles,. He felt all emergency rooms should
be adequately stocked. He used sodium ascorbate, 7.5 grams in 30 ml. The syringes are 5 to
60 cc. The needles are 20 gauge (big), one inch long to 31 gauge (I have trouble believing
this) one inch long. I get “miracle like responses.”<br />
Case 1: An eighteen-year-old female was treated just twenty minutes after a hornet
bite. She was covered with hives and had shortness of breath and difficulty swallowing. In
minutes after twelve grams of sodium ascorbate intravenously were pushed in with a 50 cc
syringe her allergic symptoms were gone.<br />
<br />
Dr. Klenner took ten grams of C dissolved in water orally and again in fifteen
minutes to counteract the stings of fifteen yellow jackets. No symptoms.<br />
<br />
Snakebite: He reported on a four-year-old girl bitten by a Highland Moccasin. She had
severe pain in her leg and was vomiting within twenty minutes after the bite.
Dr. Klenner gave four grams of C intravenously and within half an hour she had
stopped crying and could now drink orangeade and began to laugh. “I’m all right
now.” She slept well all night, but because of a slight fever and tenderness,
Dr. Klenner gave her another four grams intravenously and again that late afternoon.
No antibiotics and no anti-serum were necessary.<br />
<br />
Dr. Klenner had worked the schedule out on dogs and published it in hunting and
fishing magazines. He has had many testimonials from satisfied doctors.<br />
<br />
“All the venom that will be encountered exists as you see the patient. It is
important to give sufficient sodium ascorbate to neutralize the bite. The more you give;
the faster will be the cure. We now routinely give 10 to 15 grams sodium ascorbate
depending on the weight of the victim. Then as much of the drug as can be tolerated by
mouth is given, usually 5 grams, every four hours.”<br />
Usually without the use of Vitamin C patients are stuck in the hospital requiring
hot packs, antibiotics, anti-serum and nursing care. Many end up with much scarring.<br />
<br />
He recited the case of a man who was treated at another emergency room. The doctor
tried to cut out the local bite area.<br />
<br />
When Dr. Klenner saw him it was badly infected and the temperature was 104°.
Fifteen grams of C intravenously twice daily, 5 grams of C orally every four hours.
Penicillin injected for the infection. He was back to work in seven days.<br />
<br />
“Sodium ascorbate will cure any type of <b>snake bite</b>.” The amounts and
the speed of injection are critical. Forty to 60 grams intravenously as a starter. Klenner
cites the 6500 deaths a year from snake bites, but many more from insects, bees, spider,
plants and some caterpillars. They produce formic acid, histamine and specific toxin
albumins. Some are neurotoxins; some cause capillary damage and hemorrhage. When cells are
damaged proteins are deaminized, producing histamine and other toxic products; shock may
occur. These deaminizing enzymes from the damaged cells are inhibited by Vitamin C.
The pH of cells changes when cells are damaged; enzymes become destructive instead of
constructive. C reverses this. Vitamin C is reduced in the serum of those in shock.
350-700 mg per kg body weight is the saving intravenous dose. In children up to two grams
can be given in each of several areas (a twenty kg five year old could get two grams in
each of four sites. Ice before and after the injection would control the pain).<br />
<br />
He reports a case of a bite by a <b>Puss caterpillar</b>. The patient was going into
shock with asphyxia and cyanosis. Dr Klenner whipped out his trusty syringe, filled it
with 12 grams of C, squirted it into the man’s veins and before he was done, the
patient was improved enough to exclaim, “Thank God.” And thank Dr. Klenner
for figuring out what to do; the man would have died from shock if it had not been for the
rapid infusion of C. Again, Dr. Klenner’s maxim adds weight: Give the C while
pondering the diagnosis.<br />
<br />
<b>Mosquito bites</b>: eleven grams of C per day and 200 to 400 mg of B complex daily,
both by mouth.<br />
<br />
<b>Poison Oak or Ivy</b>: oral Vitamin C plus a paste of C powder will control the
contact allergy in 24 hours.<br />
<br />
<hr />
<br />
<h3 align="center">
Multiple Sclerosis & Myasthenia Gravis</h3>
Dr. Klenner also turned his attention to other nervous system diseases. In a paper
entitled, “Response of Peripheral and Central Nerve Pathology to Mega-doses of the
Vitamin B complex and other Metabolites,” he focuses on Multiple Sclerosis and
Myasthenia Gravis. (Journal of Applied Nutrition, Vol. 25, #304, 1973).<br />
<br />
He felt fatigue was the key to the understanding of the nervous system and its
physiology. Substances are consumed for the production of energy in the muscles. Products
of this process accumulate in the tissue. Some diseases will prevent this use of available
energy. The junction between neuron and neuron and the connection between motor nerves and
the fibers of skeletal muscle are the two locations for normal fatigue.<br />
<br />
Plants will wilt if fatigued; improper atmosphere and inadequate soil are responsible.
Animals and humans need food, oxygen and faith to stay alive and healthy. He felt a
sharecropper working in fresh open air would be less fatigued than a factory worker.
Oxygen supply has much to do with fatigue.<br />
If a muscle is repeatedly stimulated, it will become so exhausted it will fail to
respond. Either the glycogen is used up, or the lactic acid has accumulated to a poisonous
level.<br />
<br />
(At this point he describes the aerobic and anaerobic metabolism of muscles.
Phospho-creatine, adenosine triphosphate, calcium, magnesium and stored glycogen are all
necessary for muscle function. Oxygen and small amounts of protein play a part in muscle
contraction. Acetylcholine and its esterase are essential; too much or too little of any
of these substances may prevent or slow down muscle action.)<br />
<br />
Myasthenia Gravis is a disease in which too much pyruvic acid, due to faulty
metabolism, affects the interaction of acetylcholine at the junction of the nerve and the
muscle. He felt at that time that Multiple Sclerosis was due to “sluggish and bizarre
muscle activity due to the inability to utilize essential factors because of mechanical
and chemical road blocks.”<br />
<br />
He felt chemical fatigue was common. Body lassitude is the result of ingestion of
sedatives, hypnotics, tranquilizers and even sodium bicarbonate. The latter can displace
oxygen from hemoglobin, cutting down oxygenation of tissues. But Vitamin C will
prevent this type of energy loss. Smoking aggravates this fatigue.<br />
<br />
A person’s muscle exhaustion point is determined by his oxygen absorbing and
carbon dioxide discharging ability. At rest we use 200 to 300 cc of oxygen per minute.
With sudden exertion this will rise to 2000 to 4000 cc. The more oxygen absorbed, the more
lactic acid will be removed. Efficient use of oxygen is the key to adequate energy
production and removal of wastes.<br />
<br />
He described mental fatigue, active and passive. Passive is neurasthenia or brain fog:
sensations of pressure in the head, poor memory, loss of ability to concentrate,
irritability of temper, insomnia, anorexia and a variety of aches and pains.<br />
<br />
Active mental fatigue is caused by continuous work, and this change is due to the
sensory-motor exhaustion and not the mental work per se. The primary area of fatigue is at
the synapses which beg only diversion of interest and activity.<br />
<br />
Adequate oxygen is assured if the lungs and hemoglobin are normal, but also by taking
10 to 30 grams of ascorbic acid by mouth every 24 hours. Oxygen is released for tissue use
when ascorbic acid becomes dehydroascorbic acid. Enzymes are necessary to make all these
reactions possible. Genetic faults manifest themselves through enzymatic deficiencies.<br />
<br />
He outlines the nineteen stops from glucose to pyruvic acid which provides energy. This
energy release depends upon oxygen and, Dr. Klenner emphasized, it is important to
maintain good ventilation capacity, and, of course, a substantial intake of
Vitamin C.<br />
<br />
He felt pyruvic acid metabolism was important for the understanding of Myasthenia
Gravis. Coenzyme A (COA, the active form of pantothenic acid) is in limited supply in M.G.
It, COA, intercepts pyruvic acid at the end point of glucose metabolism. Another enzyme,
cocarboxylase, splits the carboxyl group (COOH) away from pyruvic acid to form CO<sub>2</sub>
and free hydrogen. The remaining two carbon fragment (acetate) join with coenzyme A to
form acetyl coenzyme A. A high energy package named NADH2 is formed from the carboxyl
group from pyruvic acid and a sulfur group from coenzyme A.<br />
<br />
Thiamin is important in all this energy production as two molecules of thiamin combined
with two molecules of phosphoric acid become cocarboxylase. This enzyme must be present
for the continuance of the metabolic cycle. When thiamin is deficient, pyruvates and
lactate accumulate, and at the neuromuscular junction the nerve end plate becomes swollen
and poorly operative. That same enzyme is necessary for the syntheses of acetylcholine,
the neurotransmitter that initiates muscle contraction. “Thiamin deficiency inhibits
lactic acid metabolism.” A thiamin deficiency means a cocarboxylase deficiency. Liver
enzymes are mainly responsible for the phosphorylation of thiamin to cocarboxylase. Liver
disease would obviously reduce this synthesis. “The activity of choline esterase
(breaks down acetylcholine) is inhibited by this same double thiamin unit.” (See also
p. 20.)<br />
In the conversion of fatty acids to energy some of the same enzymes are necessary:
coenzyme A, hydrogen carriers (niacin-adenosine-dinucleotide) and Vitamin C. The
latter acts as a hydrogen transport.<br />
<br />
He puts Myasthenia Gravis and Multiple Sclerosis in the same therapeutic group as he
found thiamin was the key to the therapy. M.G. is a genetically transmitted disease and
M.S. is triggered by a virus and mimics poliomyelitis. Nerve damage in M.S. is due to
microscopic hemorrhages in the nervous system. During healing, scar tissue contracts
clamping off capillary flow and nutrition. This wasting results in loss of the myelin
sheath protection.<br />
<br />
He felt that remyelinating these damaged nerves was every bit as hopeful as the
myelination that occurs normally in infancy with nothing more spectacular than breast
milk. It requires two years of treatment to repair the damage caused by one year of the
disease.<br />
<br />
He cites works in the late 1930s by Stern at Columbia University who used thiamin
intraspinally for the treatment of Multiple Sclerosis with astonishing results. After 30
mg of thiamin was injected into the spinal canal of paralyzed MS. victims, they had a
temporary remission. They could walk for a while. And Stern felt it was a B<sub>1</sub>
avitaminosis. It was known at that time that polyneuritis can cause degeneration of myelin
sheaths.<br />
<br />
Dr. Klenner felt that both M.G. and M.S. were basically a disturbance of supply
and demand and not a functional defect nor impaired diffusion. He followed the belief of
Dr. Leon Rosenberg (Yale) who distinguishes between vitamin deficiency diseases and
vitamin dependency diseases. Some diseases would require 1000 times the calculated minimal
daily requirement. Another investigator [Moore] used high intravenous doses of nicotinic
acid (B3) in the control of M.S.<br />
<br />
Dr. Klenner’s protocol for M.G. and M.S. in the 1950’s:
<br />
<br />
<ol>
<li>Thiamin, (B<sub>1</sub>), orally: 300 to 500 mg 30 minutes before meals and at bedtime.
Intramuscularly: 400 mg daily. Intravenously: 1000 mg (or 20 mg per kg body weight) two to
three times a week. A 20 cc to 30 cc syringe with a one inch 22 gauge (or smaller) needle
is used. The patient is to be supine and the pulse counted as the solution is injected. If
the pulse rises, the solution is being injected too rapidly. Thiamin can be toxic but as
soon as it is phosphorylated (in seconds) it becomes cocarboxylase, a necessary enzyme.
Benadryl® intramuscularly stops any allergic reaction. Dr. Klenner reassures us that
if injected slowly, no problem is encountered. The preservatives are more likely to cause
reactions than the thiamin.</li>
<li>Niacin or nicotinic acid, (B<sub>3</sub>), orally: 100 mg to 3000 mg thirty minutes
before meals and at bedtime. The dose should be enough to produce a strong body flush. As
it dilates the blood vessels—“even those that have been compressed by scar
tissue”—a greater amount of the nutrients reach the muscle and nerve cells.
Dr. Klenner felt it would be better to have a constant flush.</li>
<li>Pyridoxine, (B<sub>6</sub>), orally: 100 to 200 mg before meals and at bedtime.
Intramuscularly: 100 mg daily. Lack of B6 causes anemia and neurological lesions.
Intravenously: 300 mg. It is necessary for the metabolism of fatty and amino acids.</li>
<li>Cobalamin, (B<sub>12</sub>), intramuscularly: 1000 mcg three times a week. B<sub>12</sub>
is a factor in the synthesis of myelin. In the treatment of neurological diseases, B<sub>12</sub>
reduces the requirement of choline.</li>
<li>Ascorbic acid, orally: 10 to 20 grams are to be taken daily in divided doses.
Vitamin C will prevent a superimposed infection and aids in metabolism.</li>
<li>Riboflavin, (B<sub>2</sub>), orally: 25 mg before meals and at bedtime. Intramuscularly:
40 to 80 mg daily. It is essential for metabolism of carbohydrates and in the regulatory
function of the hormones involved in carbohydrate metabolism.</li>
<li>d-alpha tocopherol acetate, (Vitamin E), orally: 800 Units before meals and at bedtime.
A deficiency results in demyelinization and distortion of the spinal cord nerves.</li>
<li>Crude Liver, daily injections. It contains factors still unknown but essential in
metabolism. (Not manufactured now.)</li>
<li>Adenosine-5-monophosphoric acid. By adding this, all the chemistry dealing with cell
metabolism is enhanced. It is essential to muscle function and, thus, energy.</li>
<li>Choline, orally: 700 to 1400 mg after each meal and at bedtime. It is in fat and nerve
tissue. Acetylcholine plays an important role in humoral transmission of nerve impulses to
effector organs like muscles.</li>
<li>Lecithin, orally: 1200 mg of soybean lecithin after each meal. Lecithin contains
choline. It plays an important part in the structure of cell membranes. It is the lipid
used in nerve tissue.</li>
<li>Magnesium, orally: 300 mg after each meal. Muscle activity requires magnesium. It also
serves as an enzyme activator.</li>
<li>Calcium gluconate, orally: ten-grain tablets. Two tablets after each meal and bedtime.
Intravenously: one gram twice weekly. Helps muscle activity.</li>
<li>Calcium pantothenate, orally: 500 mg after each meal and at bedtime. This is a coenzyme
A. It participates in the acetylation of amines and metabolism of carbohydrates and fatty
acids.</li>
<li>Aminoacetic acid, (Glycine), orally: one heaping tablespoon of the powder in a glass of
milk four times a day. It is concerned with the syntheses of glutathione which is involved
with intracellular oxidation and reduction. It stimulates the combustion of other tissue
constituents. It has an adaptability in the detoxification process.</li>
<li>The hemoglobin should be kept to at least thirteen grams.</li>
<li>The diet is to be high protein, including two to three eggs for breakfast.</li>
<li>One Theragran-M capsule daily for trace minerals.</li>
<li>Dantrium to relieve tremors. Sysmmetrol to relieve stiffness.</li>
<li>Zinc gluconate, orally: 20 mg three times a day helps Myasthenia Gravis.</li>
</ol>
This treatment works dramatically in M.G. An abbreviated schedule can be effective. One
gram thiamin four times a day, niacin, enough to produce a flush four times a day, 200 mg
calcium pantothenate four times a day, 100 mg pyridoxine four times a day, 10 grams of C
in divided doses, glycine one tablet four times a day. This treatment is effective, but
the full therapy will afford more dramatic response.<br />
<br />
Dr. Klenner felt that most cases (80%) of Multiple Sclerosis had their origin in
an illness—probably a coxsackie virus—compatible with a summer “flu”.
He mentioned other theories of the etiology of M.S., but was convinced that the scar
tissue that forms around the nerves and produces the symptoms “is the end result of
microscopic hemorrhages following virus invasion.”<br />
<br />
He believed that in M.G. the thymus gland was hyperplastic in many cases, and that
muscle antibodies might account for others, but the importance of the excessive pyruvates
at the neuromuscular junction has to be recognized as the basic cause of the hypotonia.<br />
<br />
Here followed a number of a case histories of neurological diseases. One case of M.S.
was of a male confined to a wheel chair in the hospital for two years. After a month of
the treatment listed above his physician realized the improvement and sent him home. In
three years he was free from the disease and remained so as he continued in a modified
treatment.<br />
<br />
One M.G. case was of a male receiving prostigmine to which he was becoming
unresponsive; thiamin was given intramuscularly along with other B vitamins three times a
day. He was off the prostigmine in a year. He lived a normal life for eighteen years. He
died of an unrelated cerebral accident.<br />
<br />
A woman with polyneuritis began her illness with pain, burning and jerking of her legs
accompanied by a high fever for ten days. Paralysis on left side plus weakness of the
hands. She received oral and intramuscular injections. In several months intravenous
vitamins were begun. In sixteen months she began to move her right leg. In five years from
the beginning of the illness she began to get around with knee braces and a walker. In one
more year she was able to move about without a back brace. Dr. Klenner felt if she
had had 200 grams of ascorbic acid early, she would not have had the paralysis. She was
also given 300 mg ribonucleic acid four times a week.<br />
<br />
Another woman developed weakness in her extremities and was diagnosed as M.S.
superimposed by a viral encephalitis. She was sent home with a wheelchair and was expected
to die. She fully recovered on Dr. Klenner’s protocol and continued to take her
supplements.<br />
<br />
A male, aged 28, developed numbness and loss of muscle control from the waist down
about two years before he came to Dr. Klenner’s treatment. He also had loss of
bladder control. Dr. Klenner felt he had M.S. and put him on the above treatment. He
was so much better in five weeks that he stopped treatment but the symptoms returned in
three weeks, so he went back on the full treatment. Within a year he was back to full
employment and able to follow his hobby as a crack pistol shooter.<br />
<br />
A white 57 year old female began to be fatigued seven years before coming to
Dr. Klenner. She had normal function after a night’s sleep but had drooping
eyelids and could not chew food after a few bites. Some doctors had called it
psychosomatic. But it was quite obvious to Dr. Klenner that she had M.G. After 1000
mg of thiamin and 300 mg of pyridoxine administered intravenously in ten minute intervals,
she was able to chew and make facial movements for the first time in three years. She has
no symptoms as long as she continues the Klenner program.<br />
<br />
He was quite definite: “Any victim of Multiple Sclerosis who will dramatically
flush with the use of nicotinic acid and has not yet progressed to the stage of myelin
degeneration, as witnessed by sustained ankle clonus, can be <i>cured</i> with the
adequate employment of thiamin, B complex proteins, lipids, carbohydrates and injectable
crude liver.” “We had patients in wheel chairs who returned to normal activities
after five to eight years of treatment.” He also noted that if M.S. patients had a
course of ACTH or cortisone, it extended the recovery period.<br />
<br />
He noted the peripheral neuritis that is due to thiamin deficiency is common in chronic
alcoholism.<br />
“The treatment of M.G. is that of any pathology dealing with the interruption of
the normal physiology of nerve cells.” He had found that after successfully treating
poliomyelitis victims with Vitamin C, he had to follow up with B vitamins for the
nerve repair. He found the same results when treating damage to the spinal cord, whether
trauma or viral infection. B<sub>1</sub> restores the ability of the nervous system to
handle pyruvic acid and dextrose properly. Cocarboxylase may be the “food required
for nerve life.”<br />
<br />
Since M.G. does not suffer the loss of myelin sheaths in vital areas, it does not have
to be treated as rigorously as M.S. But the chemistry is more complex because muscles are
involved. 900 different enzymes have been identified, therefore vitamin therapy must be
intense. Of course, good liver function is necessary for good results. Dr. Klenner
stumbled on a liver test: a test tube is filled with a morning urine specimen. In 24 hours
there is usually a gelatinous mass accumulation at the bottom; the more the amount, the
more the stress to the liver. Choline will prevent this from appearing. These are
phosphates.<br />
<br />
In an article, “Fatigue—Normal and Pathological”, [Southern Medicine and
Surgery, Volume III, #9, Sept. 1949], he had already had success with the vitamin
treatment of MS. and M.G. Dr. Klenner felt that fatigue is a warning signpost along
the road of infectious disease. Heavy muscular exercise throws a great burden on the
defensive mechanisms. The tissue of the adrenal cortex of rats is increased in weight
after repeated periods of exercise.<br />
<br />
He pointed out the importance of oxygen in the etiology of fatigue. If the air that is
inhaled has but 0.1 percent of carbon monoxide, half the hemoglobin will be bound to the
CO and unavailable for carrying oxygen to the tissues.<br />
<br />
Poorly oxygenated blood can come from drugs, analgesics, and even sodium bicarbonate. A
deficiency of B<sub>1</sub> will reduce tissue (which breaks down acetylcholine needed at
the nerve ending to activate the muscle). Shots of it are to be given daily from one to
three weeks and then a 15 mg tablet orally every six hours.<br />
<br />
B<sub>1</sub>, 100 mg intramuscularly three times a day are given along with oral
glycine. The other members of the B complex were added.<br />
<br />
“Avitaminotic nerve fibers have a hunger for this vitamin (B<sub>1</sub>), and it
is easy to know when the optimum return of function is obtained. When the nerve structure
has been repaired, the patient will become irritable, the appetite will be lost and he or
she will experience a sensation of heaviness and stiffness of the muscles of the
extremities. Sufficient Vitamin C is then given by mouth to maintain optimum
therapeutics.”<br />
<br />
As to M.S. the diagnosis is determined by the “evidence of lesions affecting
chiefly the white matter, scattered in time and space: palsy of one of the oculomotor
nerves, nystagmus, slight ataxia of arms, absence of abdominal reflexes and other
scattered neurological anomalies (such as poor bladder control and patchy sensory
changes).<br />
<br />
Subtle forms of encephalitis might cause changes in the nervous system preventing a
normal supply of Vitamin B<sub>1</sub> from reaching distal parts of the nervous system.
He noted the increased incidence of M.S. after the encephalitis epidemic of 1920-26 and in
1934. Also unrecognized cases of poliomyelitis may be an important factor in the cause of
avitaminotic symptoms in the central nervous system. This could happen in these disease
conditions even with sufficient B<sub>1</sub> in the diet; the vitamin is not diffused
properly. Initially it is the virus and when that dies down, it is scar tissue blocking
the circulation. The capillaries must be opened and extra B<sub>1</sub> must be supplied
with the protocol cited above.<br />
<br />
In a letter to the editor of the Tri-State Medical Journal, Oct. 1954, he boldly stated
that he was curing Myasthenia Gravis. He seemed more definite about the biochemistry:
pyruvic acid, if allowed to accumulate, will produce a cloudy swelling of the distal
portion of nerves, and that the primary biochemical fault in B<sub>1</sub> deficiency is
the failure of the organism to metabolize pyruvic acid. Also he realized that creatine
(needed for normal muscle function) is formed by the body when choline and urea combine.
Choline is in short supply in M.G. unless supplemented orally. He felt glycine should be
supplemented in the diet because it yields urea. Protein is needed in the diet to sustain
muscle wear and tear. Tyrosine is needed to help turn ingested protein into usable amino
acids and Vitamin C is essential in this reaction.<br />
<br />
This leads us to paper he put together in 1980. It was not published: “<b>Multiple
Sclerosis Diagnosis and Treatment</b> Suggestions.”<br />
<br />
He again stated the origin was due to a childhood virus of the coxsackie group
mimicking red measles. The initial illness was a severe lung infection, or an encephalitis
which subsided only to recur as M.S. twenty to thirty year later. 70% of cases have the
onset of their M.S. symptoms from the age of 20-40 years.<br />
<br />
40% will have optic neuritis as the initial symptom, then optic atrophy may follow.
Most will notice double vision early. Weakness, loss of reflexes, numbness in fingers,
dizziness, loss of position sense, feeling heat over spine, rheumatoid arthritis may occur
concurrently (shortage of B vitamins), intention tremor, poor bladder control, and spastic
paraplegia.<br />
<br />
His treatment suggestion for M.S. at this time (1980) consisted of:
<br />
<br />
<ol>
<li>Thiamin HCl (Vitamin B<sub>1</sub>) one gram (1000 mg) taken thirty minutes before meals
and at bedtime.</li>
<li>Nicotinic Acid (Niacin; Vitamin B<sub>3</sub>) 50 mg to 300 mg, depending on flushing of
skin, thirty minutes before meals and bed time.</li>
<li>Riboflavin (Vitamin B<sub>2</sub>) 250 mg after meals and bed time.</li>
<li>Pyridoxine (Vitamin B<sub>6</sub>) 100 mg after meals and bed time.</li>
<li>Calcium pantothenate (pantothenate acid/Vitamin B<sub>5</sub>) one gram after meals and
bed time.</li>
<li>Lecithin. 1200 mg (19 grains) one capsule after meals and at bed time with two percent
milk.</li>
<li>Vitamin A (palmitate) one 50,000 unit capsule after breakfast and supper.</li>
<li>Vitamin E (d-alpha tocopheryl acetate) 400 I. units. Four capsules at bedtime.</li>
<li>Niacinamide (Vitamin B<sub>3</sub> amide) 500 mg. tablets. One after meals.</li>
<li>Magnesium oxide 300 mg tablet. One tablet after meals and before bed time.</li>
<li>Trinsicon or Feosol. One capsule twice daily or sufficient to maintain a hemoglobin of
at least thirteen grams.</li>
<li>Folic acid. Two milligrams after each meal. Only recommended when the hemoglobin will
not respond to iron treatment.</li>
<li>Sunflower seed oil capsules. One capsule after meals and bed time.</li>
<li>Lipotriad. Three capsules yields 700 mg of choline. Two capsules after each meal. It is
used as a methylating agent.</li>
<li>Calcium gluconate, 10 grain tablets. Twelve tablets daily. May be omitted if patient can
drink a quart of milk a day.</li>
<li>Linseed oil capsules. One capsule after meals and at bedtime. Contains linolenic, oleic
and linoleic acids.</li>
<li>Muscle relaxants. Prescribed according to patient needs.</li>
<li>Calcium Orotate (Vitamin B13) 500 mg tablet. One after meals and at bed time.</li>
<li>Calcium pangamate, 50 mg tablet. One tablet twice daily.</li>
<li>Protein supplement containing eighteen amino acids. One ounce in a glass of milk four
times a day. Some of the above can be taken with this drink.</li>
</ol>
[This list was originally numbered 1) to 22), with 11) and 12) missing –ed.]<br />
Intramuscular injection, given five to seven days each week.:
<br />
<br />
<ol>
<li>2 cc crude liver daily. (Hard to get now. I can’t find it.)</li>
<li>2cc Thiamin HCl, (B<sub>1</sub>), 400 mg daily.</li>
<li>1.5-2cc Pyridoxine, (B<sub>6</sub>), 150 mg daily. Add to B<sub>12</sub>.</li>
<li>1.5-2cc Cyariocobalamin, (B<sub>12</sub>), 1500 mcg daily. Add to B<sub>6</sub>.</li>
<li>1.5-2cc Riboflavin, (B<sub>2</sub>), 75 mg daily. Add to B<sub>3</sub> amide.</li>
<li>1.5-2cc Niacinamide, (B<sub>3</sub>), 150 mg daily. Add to B<sub>2</sub>.</li>
</ol>
Some of the above vitamins are given one to three times each week:<br />
<br />
Thiamin HCl, 1000 mg; Pyridoxine, 300 mg; Niacinamide, 500 mg; dilute these to 20 cc
with saline solution or best, sodium ascorbate (250 mg/cc). Give slowly with a 23 gauge
needle, one inch long. Pulse is taken during the injection; if the pulse rises, the
injection speed is slowed.<br />
<br />
He found that RNA and DNA tablets, 100 mg of each, were helpful to some patients; one
to three of each daily along with the other vitamins. Inositol, 500 mg, one to three times
a day may help.<br />
Because of the large number of pills and capsules to be taken daily, Dr. Klenner
suggested they be put into a blender along with a protein powder, milk, vanilla, and carob
to make a tasty drink. They all might go down more easily.<br />
<br />
He cited some cases:
<br />
<br />
<ol>
<li>Female developed weakness in extremities in 1961 (refer to page 48). She was sent home
to deteriorate. Dr. Klenner began his program, and she is now cured and has been
leading an active life for over 21 years. “The central nervous system can be
regenerated, but it does require time. Ten years was given to the restitution of her
entire nervous pathways.” She is “full of vim, vigor, and vitality.”</li>
<li>Another woman had complete paralysis of both legs and left arm. She required a steel
brace from hips to neck. After two years of this she was taken to Dr. Klenner and
started on the above therapy. In sixteen months she could move her right leg and left arm.
In three years she began to move her left foot and button her blouse. In nine years she
could stand unaided. A modem day miracle, “Enzyme, co-enzyme, and metabolite theory
is the correct approach to the rehabilitation of the central system.”</li>
<li>In 1918 a male was diagnosed as M.S. because of blurred vision, numbness, and low back
pain. In four months Dr. Klenner began his program and in six months the man was back
driving the fire truck. He continued to improve and cut firewood during off hours. Early
M.S. cases will respond quickly.</li>
<li>Another female with dizziness, poor vision, lateral, and rotatory nystagmus (dancing
eyeballs). The nausea was so profound; she could not swallow the oral vitamins. But after
one year of the vitamin injections she could do the oral route. From not being able to
read a billboard, she can now read large type books. The nystagmus is gone, but she needs
a cane to ambulate.</li>
</ol>
<br />
<hr />
<br />
<h3 align="center">
Complications</h3>
Dr. Klenner reports on a few minor complications. Some diarrhea might have been
due to sodium bisulfite. Induration after intramuscular injections was found to be due to
the Vitamin C not being injected deeply enough into the muscle. (One had to be
drained—a sterile abscess.) If the concentration was one gram to 5 cc it caused a
vein spasm up the arm from the injection site in three cases. A thrombosis of the vein
occurred in but one case. A minor face rash developed in a few that cleared after the C
was stopped.<br />
<br />
Calcium seemed to enhance the effects of the C when both were give simultaneously. But
a gram of just the calcium given intravenously can slow the heart rate to a dangerous
degree.<br />
<br />
<hr />
<br />
<h3 align="center">
Safety</h3>
He has some reassuring words for those who feel kidney stones are an automatic result
of large doses of Vitamin C. He says in all cases a stasis of urine flow “and a
concentrated urine appear to be the chief physiological factors.” Oxalic acid
precipitates out of solution only from a neutral or alkaline solution—pH 7 to pH 10.
Urine pH in those consuming ten grams of Vitamin C daily is about 6. Even in
diabetics who take this large amount of C (10 grams), the urinary oxalate excretion
remains relatively unchanged. “Vitamin C is an excellent diuretic. No urinary
stasis; no urine concentration. The ascorbic acid/kidney stone story is a myth.” One
more bon mot: “Methylene will dissolve calcium oxalate stones, if the patient is
given 65 mg orally two to three times a day,” he learned from Medical World News
(Smith, M.J.V., M.D.: Dec. 4, 1970).<br />
<br />
(90% of all stones are calcium stones. Calcium is soluble in acid media. Vitamin C
acidifies the urine. Acid urine discourages the growth of bacteria. Although uric acid
stones are theoretically possible with high doses of C and a low urinary pH, none have
been reported.)<br />
<br />
A report in N.E.J.M. on 11 Feb, 1971 [Merton Lamden] suggested that large doses of C
might cause diabetes in humans. The experiment was done in rats, but the dose translation
in humans would have amounted to 5000 grams! [Paterson] Maybe there is a toxic dose.
(Dr. Klenner at the time of that writing had been on 10 to 20 grams of C daily for
eighteen years. No diabetes, and no kidney stones). This study has no relationship to the
use of therapeutic doses of C.<br />
<br />
Lamden found that an ingestion of 9 grams of C/day resulted in oxalate spills of 68 mg.
in the urine per 24 hours. Controls without C spilled 64 mg./24 hours. Not a big
difference.<br />
<br />
He reiterates the safety of large doses of C. He states that plasma doses of greater
than twenty times normal produce no ill effects. Diarrhea is the most common side effect
of large doses. Some notice thickening of subcutaneous tissue is the C is not injected
deeply enough into, the muscle. (That induration will eventually resolve.) Some will
complain of venous irritation and spasm if the intravenous Vitamin C is too
concentrated or too rapidly injected. (C mixed with calcium will reduce this irritation.)
A rare thrombosis may occur if the concentration of the C is greater than 500 mg per cc.
Some will faint if the injection is given too rapidly. (It is best to have the patient lie
flat.) Large doses by mouth may cause a genital or anal rash and itch.<br />
<br />
He also showed how safe large doses of C were. He gave 200 patients 500 to 1000 mg of C
every four to six hours for five to ten days. No laboratory abnormalities were found in
blood or urine and no symptoms were noted except one percent who developed vomiting; he
assumed from a hypersensitive stomach. And these patients had no virus infection to
“assist in destroying the vitamin.”<br />
<br />
One volunteer received 100,000 mg in a twelve day period; no problems.<br />
<br />
<hr />
<br />
<h3 align="center">
Reluctance by Orthodox Medicine to Accept</h3>
Dr. Klenner knew all this way back thirty to forty years ago. Why has the medical
community taken so long to use this cheap, safe, and valuable tool to control infections?
Dr. Irwin Stone, Dr. Linus Pauling, and Dr. Robert Cathcart have tried to popularize this
method and were only met with poor press and ridicule. Are the drug manufacturers
organized into a conspiracy too powerful to overcome? M.D. types will believe what is
published in their favorite medical journals, but Vitamin C therapy studies are not
seen in medical journals because much of the income to the publishers comes from drug
manufacturers. Vitamin C use represents a threat to their income; it cannot be
patented. Maybe if patients demanded the therapeutic use of Vitamin C from their
doctors, the doctors would become familiar with its use and add it to their therapeutic
tools. Their colleagues would hoot: “Ha ha, you are a quack. You were suckered into
that.”<br />
<br />
The doctor could respond: “I didn’t want to, but the patient made me do
it.”<br />
<br />
But the evidence for its use seems to be there, right in the medical literature, but
how many read the Journal of Preventative Medicine?<br />
<br />
Dr. Klenner writes clearly and cogently. He is cheerful, even enthusiastic. And I
find no bitterness due to the frustrations about the poor acceptance of his research by
the medical establishment. He had done his own literature search and finds plenty of
confirmation for his therapies in animal and human experiments.<br />
<br />
“Many physicians refuse to employ Vitamin C in the amounts suggested, simply
because it is counter to their fixed ideas of what is reasonable.” The new products
advertised by an alert drug company are okay to them. Dr. Klenner tells of many
letters from doctors who used this C treatment on poliomyelitis—in patients, their
own children and even themselves. They were cured.<br />
<br />
Dr. Klenner commented that if these spectacular results had been produced at a
teaching and research center and then published, the medical community might pay some
attention and the use of C would become standard and routine. “There is no doubt that
physicians are being brainwashed with the current journal advertising.” He uses an
appropriate quote from Herber Spencer, “… to keep a man in everlasting
ignorance… condemnation without investigation.”<br />
<br />
He blamed the National Research Council who planted the concept in doctors’ brains
that any dose above 125 mg per day is spilled by way of the kidneys. It was like any drug,
the council implied, and more was no more effective than the dinky dose that protected the
human from scurvy. Doctors do not seem to realize that the need for C is different
“in each one of us either because of the individual kidney threshold level or because
of greater requirements necessitated by pathology.”<br />
<br />
<hr />
<br />
<h3 align="center">
A Few Quotes</h3>
He reminds us of Hippocrates. He felt that of several remedies physicians would choose
the least sensational. Vitamin C meets those requirements.<br />
<br />
“Adults taking at least ten grams of ascorbic acid daily and children under ten at
least one gram for each year of life will find that the brain will be clearer, the mind
more active, the body less wearied, and the memory more retentive.”<br />
<br />
Another summary by Dr. Klenner: “I have never seen a patient that
Vitamin C would not benefit.”<br />
<br />
He discovered the tremendous therapeutic power of Vitamin C to aid the immune
system, to act as an antihistamine, and to neutralize toxins.<br />
<br />
Again, let us not forget
what comes through after examining all these published reports: “Vitamin C
should be given to the patient while the doctors ponder the diagnosis.”<br />
<br />
<hr />
<br />
<h3 align="center">
References</h3>
Page II:
<br />
<br />
<ul>
<li>Pauling, L.: <i>Vitamin C and the Common Cold</i>; W. F. Freeman & Co. San
Francisco, 1970.</li>
<li>Brody, H.D.: <i>J. Amer. Diet. Assoc.</i>, 29: 588, 1953.</li>
</ul>
Page 2, How it Works:
<br />
<br />
<ul>
<li>Klenner, F.R.: Virus Pneumonia and its Treatment with Vitamin C. <i>Southern Med. Surg.</i>,
Feb. 1948</li>
<li>Klenner, F.R.: Encephalitis as a Sequela of the Pneumonias. <i>Tri-State Med. J.</i>,
Feb. 1960.</li>
<li>Klenner, F.R.: An Insidious Virus. <i>Tri-State Med J</i>, June 1957.</li>
<li>Burns, J.J., et al: J. Biol. Chem., 207:679, 1954.</li>
<li>Salomon, L.L., Conney, A.H., et al: <i>NY Acad Science</i>, 92:115, 1961.</li>
<li>Burns. J.J.: <i>Am. J. Med.</i> 26:740, 1959.</li>
<li>Stone, I.: Brief proposal. <i>Per. Biol Med.</i>, Autumn, 1966.</li>
</ul>
Page 1-2:
<br />
<br />
<ul>
<li>Arber, E: <i>The Story of the Pilgrim Fathers</i>, 1897.</li>
<li>Correspondence with colleague from Puerto Rico.</li>
<li>Kline, A.B. and Eheart, M.S. Variations in the Ascorbic Acid Requirements for Saturation
of Nine Normal Young Women, <i>J. Nutrition</i> 28: 413, 1944.</li>
<li>Joliffe, N. Preventive and Therapeutic Use of Vitamins, <i>JAMA</i>, 129:613, 1945.</li>
<li>Crandon, J.H., Lund, C.C. and Dill, D.B.:. Experimental Human Scurvy. <i>N Eng J Med.</i>,
223: 353, 1940.</li>
</ul>
Page 2-3:
<br />
<br />
<ul>
<li>Klenner, F.R.: Massive Doses of Vitamin C and the Virus Diseases. <i>J. So. Med.
& Surg.</i>, 113:#4, Apr. 1951.</li>
<li>Larson, C.: <i>Ordinace</i>, pp. 359-360, Jan-Feb, 1967.</li>
</ul>
Page 3:
<br />
<br />
<ul>
<li>Starr, T.J.: <i>Hospital Practice</i>, 52, Nov 1968.</li>
<li>Kropowski, H.: <i>Med. World News</i>, p 24, June 19,, 1970.</li>
<li>Lojkin cited in Klenner’s paper: Massive Doses of Vitamin C and the Virus
Diseases.</li>
<li>McCall, C.E., and Copper, R.,: Vitamin C Shows Promise as a Bactericidal Agent. <i>Bowman
Gray School Med. Alumni News</i>, 14:1, Feb, 1972</li>
<li>Wintrobe, M.M.: <i>Clinical Hematology</i>, Lea and Febiger, 3rd Ed 1952.</li>
<li>Nossal, G. Most Killed Vaccines in Use not Termed Fit for a Mouse. <i>Medical Tribune</i>,
Apr. 5, 1972.</li>
<li>Kiegler, Guggenheim and Warburg: Vitamin C vs. Toxins, 1938. (No reference cited.)</li>
</ul>
Page 4:
<br />
<br />
<ul>
<li>Harde and Benjamin (1934-1935) found the Vitamin C fraction of the adrenal glands
greatly reduced in monkeys killed or paralyzed by the virus of poliomyelltis.</li>
<li>Yavorsky, Almoden and King (1934) reported identical findings in humans having died of
various infectious agents.</li>
</ul>
Page 4,5:
<br />
<br />
<ul>
<li>Klenner, F.R.: An Insidious Virus. <i>Tri-State Med. J.</i>, June 1957</li>
<li>Klenner, F.R.: Virus Pneumonia and its Treatment with Vitamin C. <i>Southern Med. Surg.</i>,
Feb. 1948.</li>
<li>Klenner, F.R.: Encephalitis as a Sequela of the Pneumonias. <i>Tri-State Med J.</i>,
Feb, 1960</li>
<li>Gothlin, G.F.: A Method of Establishing the Vitamin C Standard of Requirement of
Physically Healthy Individuals by Testing the Strength of Their Capillaries. (No reference
cited.)</li>
<li>Baker, A.B. and Noran, J.A.: Changes in the Central Nervous System Associated with
Encephalitis Complicating Pneumonia. <i>Archives of Internal Med.</i>, Vol 76: 146-153,
July-Dec. 1945.</li>
<li>Krumholz, S. and Luhan, J.A.: Encephalitis Associated with Herpes Zoster. <i>Arch Neur
Psych</i>, 53: 59-67 Jan-Jun, 1945.</li>
<li>Bakay, L,: <i>The Blood-Brain Barrier</i>, C. C. Thomas, Pub., Springfield, IL 1956</li>
<li>Chambers, R. and Zweifach, B.W.: Intercellular Cement and Capillary Permeability, <i>Physiol Rev.</i>,
27: 436-463, 1947.</li>
<li>Youmans, J.B.: <i>Nutritional Deficiencies</i>, 1941.</li>
</ul>
Page 5:
<br />
<br />
<ul>
<li>Hawley, E.E., Frazer, J.P., Button, L.L. and Stevens, D.J.: The Effect of the
Administration of Sodium Bicarbonate and of Ammonium Chloride on the Amount of Ascorbic
Acid Found In the Urine. <i>J. Nutrition</i>, 12:215 (August) 1936.</li>
<li>Klenner, F.R.: Significance of High Daily Intake of Ascorbic Acid in Preventive
Medicine. <i>J. Intl Acad Prev Med.</i>, 1:45-69, Spring, 1974.</li>
<li>Klenner, F.R.: Use of Vitamin C as an Antibiotic. <i>J. of Appl Nutrit.</i>, 6:
1953 (Paper presented at AAN Convention, May, 1963, Pasadena, CA.)</li>
</ul>
Page 6, Dosage:
<br />
<br />
<ul>
<li>Klenner, F.R.: Massive Doses of Vitamin C and the Virus Diseases. <i>J. So Med
& Surg</i>, 113: #4, Apr. 1951.</li>
<li>Shaw, et al: Acute and Chronic Ascorbic Deficiencies in Rhesus Monkeys. <i>J. Nutrition</i>,
29: 365, 1945</li>
<li>Rivers, T.M.: Immunological and Serological Phenomena in Poliomyelitis. Lecture III,
Infantile Paralysis, 1941.</li>
</ul>
Page 7:
<br />
<br />
<ul>
<li>Klenner, F.R.: Significance of High Daily Intake. op cit.</li>
</ul>
Page 8:
<br />
<br />
<ul>
<li>Klenner, F.R.: Use of Vitamin C as an Antibiotic, op cit.</li>
</ul>
Page 9 Tests:
<br />
<br />
<ul>
<li>Klenner, F.R.: A New Office Procedure for the Determination of Plasma Levels for
Ascorbic Acid. <i>Tri-State Med J.</i>, 5, 1956.</li>
</ul>
Lingual tests:
<br />
<br />
<ul>
<li>Ringsdorf, W.M. & Cheraskin, E.: <i>Sec. Oral Med.</i>, U of AL Med Center,
Birmingham, AL</li>
</ul>
Page 9-16, Insidious Virus:
<br />
<br />
<ul>
<li>Klenner, F.R.: An Insidious Virus, op cit.</li>
<li>Klenner, F.R.: The Clinical Evaluation and Treatment of a Deadly Syndrome Caused by an
Insidious Virus. <i>Tri-State Med J.</i>, Oct. 1958.</li>
</ul>
Page 15, Virus Pneumonia:
<br />
<br />
<ul>
<li>Klenner, F.R.: Virus Pneumonia and its Treatment with Vitamin C. <i>So Med & Surg</i>,
Feb. 1948.</li>
<li>Klenner, F.R.: Encephalitis as a Sequela of the Pneumonias. op cit ibid.</li>
</ul>
Page 15, (Herpes Encephalitis):
<br />
<br />
<ul>
<li>Lerner, M, et al: Detecting Herpes Encephalitis Earlier. <i>Med World News</i>, May 20,
1972.</li>
</ul>
Page 15, (X-ray Therapy):
<br />
<br />
<ul>
<li>Oppenheimer, A.: Roentgen Therapy of Virus Pneumonia. <i>Amer J of Roentgen</i>., 49:
#5.</li>
</ul>
Page 17-21, Poliomyelitis:
<br />
<br />
<ul>
<li>Klenner, F.R.: The Treatment of Poliomyelitis and Other Virus Diseases With
Vitamin C. <i>So Med & Surg</i>, Vol. 111: #7, July 1949.</li>
<li>Klenner, F.R., The Vitamin and Massage Treatment for Acute Poliomyelitis. <i>So Med
& Surg</i>, 114: #8, August 1952.</li>
<li>Klenner, FR.: Poliomyelitis—Case Histories. <i>Tri-State Med J.</i>, Sept 1956.</li>
<li>Sabin, A.B.: Vitamin C in Relation to Experimental Poliomyelitis. <i>J Exp Med.</i>,
69: 507, 1939.</li>
<li>Heaslip, Australian <i>J. Exp Biol. & Med.</i>, 1948.</li>
<li>Jungeblut, C.W.: Vitamin C Therapy and Prophylaxis in Experimental Poliomyelitis. <i>J
Exper Med.</i>, 65; 127, 1937.</li>
<li>Jungeblut, C.W.: Further Observations on Vitamin C Therapy in Experimental
Poliomyelitis. <i>J. Exper. Med.</i>, 66: 450, 1937.</li>
<li>Bodian, D. and Horstmann, D.:. Review of Their Work. <i>JAMA</i>, 149: Aug30, 1952.</li>
</ul>
Page 22-23, Hepatitis:
<br />
<br />
<ul>
<li>Freebern, R.K. & Repsher, LR.: <i>Med. World News</i>, Jan 23, 1970.</li>
<li>Klenner, F.R.: Unpublished paper.</li>
<li>Klenner, F.R.: Significance of High Daily Intake. op cit., page 56.</li>
<li>Klenner, F.R.: Massive Doses of Vitamin C, op cit.</li>
<li>Klenner, F.R.: Observations on the Dose and Administration, op cit.</li>
</ul>
Page 23-24, Herpes:
<br />
<br />
<ul>
<li>Klenner, F.R.: Significance, ibid, page 64.</li>
<li>Stephens, J.C. and Cook, M.: Cases of the Hidden Herpes Virus, <i>Med World News</i>,
May 26, 1972.</li>
<li>Goodpasture, E.W.: Case of the Hidden Herpes Virus. <i>Med World News</i>, Feb 25, i972.</li>
<li>Roizman, B. et al: Tracing Herpes Viruses. <i>Med World News</i>, Oct 1, 1971.</li>
<li>Klenner, F.R.: Use of Vitamin C as an Antibiotic. op cit.</li>
</ul>
Page 24-25, Chickenpox and Measles:
<br />
<br />
<ul>
<li>Klenner, F.R.: Massive Doses, op cit.</li>
<li>Klenner, F.R.: The use of Vitamin C as an Antibiotic. op cit.</li>
</ul>
Page 26, Infectious Mononucleosis:
<br />
<br />
<ul>
<li>Hellne, C. and Helene, W.: EB Virus in the Etiology of Infectious Mononucleosis, <i>Hosp
Pract.</i>, July, 1970.</li>
<li>Niderman, College Findings tie Mono to ED virus. <i>Med World News</i>, Dec 1968.</li>
<li>Klenner, F.R.: Observations of the Dose and Administration. op cit.</li>
</ul>
Page 27,
<br />
<br />
<ul>
<li>Klenner, ER.: Unpublished work on RMSF and tick bite fever.</li>
</ul>
Page 28 Trichinosis:
<br />
<br />
<ul>
<li>Klenner, F.R.: The Treatment of Trichinosis with Massive Doses of Vitamin C and
Para-aminobenzoic Acid. <i>Tri-State Medical J.</i>, April i954.</li>
</ul>
Page 30, Urethritis:
<br />
<br />
<ul>
<li>Rous, S.: Urethritis in Men. <i>NY Soc Med.</i>, Dec 15, 1971.</li>
</ul>
Page 30, Antabuse:
<br />
<br />
<ul>
<li>Klenner, F.R.: Unpublished paper.</li>
</ul>
Page 31, Arthritis:
<br />
<br />
<ul>
<li>Klenner, F.R.: Significance. op cit.</li>
<li>Abrams, E. and Sandson, J.: <i>Ann Rheum Dis.</i>, 27: 1964.</li>
</ul>
Page 31, Cancer
<br />
<br />
<ul>
<li>Klenner, F.R.: Unpublished paper.</li>
<li>Schiegel, G.E. et al: The Role of Ascorbic Acid in the Prevention of Bladder Tumor
Formation. <i>Trans Amer Assn Genitour Surg.</i>, 61: 1969.</li>
</ul>
Page 33-34, Cholesterol and Arteriosclerosis:
<br />
<br />
<ul>
<li>Ginter, E.L.: Cholesterol and Vitamin C. <i>Amer J Clin Nutr.</i>, 24: 1238-1245, 1971.</li>
<li>Spittle, C., Atherosclerosis and Vitamin C. <i>Lancet</i>, II: 1280-1281, 1971.</li>
<li>Ginter, E.: Effects of Dietary Cholesterol on Vitamin C Metabolism in laboratory
animals. <i>Acta Med Acad Sci.</i> Hungary. 27:23-29; 1970.</li>
<li>Ginter, E., et al: The Effects of Ascorbic Acid on Cholesterolemia in Healthy Subjects
with Seasonal Deficit of Vitamin C. <i>Nutr Metabol</i>, 12: 76-86. 1970.</li>
<li>Willis, G.C.: An Experimental Study of the Intimal Ground Substance in Atherosclerosis. <i>Can
Med Assoc J.</i>, 69: 17-22, 1953.</li>
<li>Shafer, J.: Ascorbic Acid and Atherosclerosis. <i>Amer J Clin Nutr.</i>, 23:27, 1970.</li>
<li>Stamler, J.: <i>Comprehensive Treatment of Essential Hypertensive Diseases</i>.
Monograph on Hypertension, Merck, Sharp and Dohme.</li>
<li>Hecker, R.R. et al: <i>J Am Chem Soc.</i>, 75:2020, 1953.</li>
</ul>
Page 34, Corneal Ulcers:
<br />
<br />
<ul>
<li>Boyd,T.A., & Campbell, F.W.: <i>B Med J.</i>, 2:1145, Nov 1950.</li>
</ul>
Page 35, Glaucoma:
<br />
<br />
<ul>
<li>Virno, M.: <i>Eye, Ear, Nose and Throat Monthly</i>, 46:1502.</li>
</ul>
Page 35, 36 Pregnancies:
<br />
<br />
<ul>
<li>Greenblatt, R.B.: <i>Obst & Gyn</i>, 2:530, 1953.</li>
<li>King, C.C. et al, <i>New York Times</i>, Nov 2, 1952.</li>
</ul>
Page 36-39, Schizophrenia, Heat Stroke, Sunburn, Slipped Disc, Toxins and Heavy Metal
Poisonings:
<br />
<br />
<ul>
<li>Klenner, F.R.: Significance of High Daily Intake,. op cit.</li>
<li>Klenner, F.R.: The use of Vitamin C as an Antibiotic, op cit.</li>
<li>Mokranjac, M. and Petrovic, C.: Report on Mercury Studies in Guinea Pigs in Relation to
Amounts of Vitamin C Administered. <i>Cr Acad Sci.</i>, Paris.</li>
<li>Dannenburg, A.M. et al: Ascorbic acid in the treatment of chronic lead poisoning. <i>JAMA</i>,
114:1439-1440, 1940.</li>
<li>Pelletier, O.: Experiments with smokers and non-smokers. JAMA, April 1969.</li>
<li>Mayers, B.W.: Where there’s smoke there may be carbon monoxide. <i>Med World News</i>,
Jan 21, 1972.</li>
<li>Hoffer, J.: Use of Ascorbic Acid with Niacin in Schizophrenia. <i>Can Med J.</i>, Nov 6,
1971.</li>
<li>Hawkins, D.: Back to Reality the Megavitamin Way. <i>Med World News</i>, Sept 24, 1971.</li>
<li>Greenwood, J.: Optimum Vitamin C Intake as a Factor in the Preservation of Disc
Integrity. <i>Med Ann DC</i>, 33:6, June 1964.</li>
<li>Massell, B.F. et al: Antirheumatic Activity of Ascorbic Acid in Large Doses. <i>New Eng
J Med</i>, 1950.</li>
<li>Kyhos, E.D. et al: Large Doses of Ascorbic Acid in Treatment of Vitamin C
Deficiencies. <i>Arch Int Med.</i>, 75:407, 1945.</li>
<li>Dalldorf, G.: <i>Vitamin C in Health and Disease.</i> W.B. Saunders, 1945.</li>
<li>Musser, J.H.: <i>Nutrition in the Aged</i>. W.B. Saunders Co., 1945.</li>
</ul>
Page 36, Burns:
<br />
<br />
<ul>
<li>Knisely, M.H. et al: <i>Arch Surg</i>, 51:220, 1945</li>
<li>Knisely, M.H.: <i>Science</i>, 106:431, 1947.</li>
<li>Berkeley, W.T., Jr.: <i>So Med J.</i>, 58:1182-1184.</li>
<li>Lund & Levenson: <i>Arch Surg.</i>, 55:557,1947.</li>
<li>Bergman, H.C. et al: <i>Am Hrt J.</i>, 29:506-512, 1945.</li>
<li>Lam, C.R.: <i>Col Rev Surg Gyn & Obst.</i>, 72:390-400, 1941.</li>
<li>Klasson, D.H.: <i>NY J Med.</i>, 51:2388-2392, Oct, 1951.</li>
</ul>
Page 37, Surgery, Shock;
<br />
<br />
<ul>
<li>Chambers, R. & Pollock, J.: <i>J Gen Physiol</i>, 10:739, 1927</li>
<li>Clark & Rassiter: <i>Q J Exp Physiol.</i>, 32:279, 1944.</li>
<li>Barlett, M.K. et al: <i>NEJM</i>, 226:474, 1942.</li>
<li>Laninan, T.H. & Ingalls, TB.: <i>Am Surg.</i>, 105:616, 1937.</li>
<li>Schumacher: <i>Ohio State Med J.</i>, 42:1248, 1946.</li>
</ul>
Page 41-42, Poisonous Insects and Reptiles:
<br />
<br />
<ul>
<li>Klenner, F.R.: <i>Hunting and Fishing Magazine</i>, April, 1950.</li>
</ul>
Pages 43-54, Myasthenia Gravis and Multiple Sclerosis:
<br />
<br />
<ul>
<li>Klenner, F.R.: Response of Peripheral and Central Nerve Pathology to Megadoses of the
Vitamin B Complex and other Metabolites. <i>J Appl Nutrit.</i>, 25:#304, 1973.</li>
<li>Klenner, F.R.: Multiple Sclerosis Diagnosis and Treatment Suggestions. Original paper,
unpublished.</li>
<li>Klenner, F.R.: Fatigue—Normal and Pathological with Special Consideration of
Myasthenia Gravis and Multiple Sclerosis. <i>So Med & Surg.</i>, 111:#9, Sept 1949.</li>
</ul>
Page 45:
<br />
<br />
<ul>
<li>Stern, E. I.: The Intraspinal Injection of Vitamin B<sub>1</sub> for the Relief of
Intractable Pain, and for Inflammatory and Degenerative Diseases of the Central Nervous
System. <i>Am J Surg.</i>, 34:495, 1938.</li>
<li>Rosenberg, L.E.: Vitamin Deficiency Diseases and the Vitamin Dependent Diseases with
Reference to B and D., <i>National Health Federation Bulletin</i> Vol XVIII. #10, Nov
1972.</li>
<li>Moore, M.T.; Treatment of Multiple Sclerosis with Nicotinic Acid and Vitamin B<sub>1</sub>.
<i>Arch Int Med.</i>, 65:18, Jan 1940.</li>
</ul>
Other supportive articles from the medical literature:
<br />
<br />
<ul>
<li>Kempe, C.H.: A Key to the Secret of M.S., <i>Med World News</i>, July 7, 1972.</li>
<li>Schandl, D.K.: Dissertation on Environmental and Pyridoxine cause of M.S., <i>The
Charlotte Observer</i>, Charlotte, N.C., April 23, 1973.</li>
<li>Brickner, R.M.: A Critique of Therapy in M.S., <i>Bull Nue Inst NY.</i>, 4:665, April
19367.</li>
<li>Zimmerman, H.H. and Burack, E.: Lesions of the Nervous System Resulting from a
Deficiency of the Vitamin B complex. <i>Arch Path.</i>, 13:207, Feb 1932.</li>
<li>Spies, T.D. et al: The Use of Nicotinic Acid in the Treatment of Pellagra. <i>JAMA</i>,
110:622, Feb 1938.</li>
<li>Spies, T.D. and Aring, C.D.: The Effect of Vitamin B<sub>1</sub> on the Peripheral
Neuritis of Pellagra, <i>JAMA</i>, 110:1081, April, 1938.</li>
</ul>
Page 55, Toxic Doses:
<br />
<br />
<ul>
<li>Patterson, J.W.: <i>J Biol Chem.</i>, 81-88, 1950.</li>
<li>Lambden, M.P. et al: <i>Proc Soc Exp Biol Med.</i>, 85:190-192, 1954.</li>
</ul>
Need for Vitamin C:
<br />
<br />
<ul>
<li>Sabin: <i>J Exp Med.</i>, 89:507-515, 1939.</li>
<li>Wright: <i>Ann Int Med.</i>, 12, 4:516-528, Oct 1938.</li>
<li>Brody, H.D.: <i>J Am Diet Assn.</i>, 29:588, 1953.</li>
<li>Regnier, E.: <i>Rev of Allergy</i>, 22:948, Oct 1968.</li>
</ul>
<br />
<hr />
Adapted from <i>Vitamin C as a Fundamental Medicine: Abstracts of Dr. Frederick
R. Klenner, M.D.’s Published and Unpublished Work</i>,<br />
ISBN 0-943685-13-3, first printing 1988.<br />
Page references apply to original publication.<br />
HTML Revised 03 July, 2004.<br />
Corrections and formatting © 2004 AscorbateWeb<br />
<i><a href="http://expozium.com/klenner_ascorbate.html">Clinical Guide to the Use of Vitamin C</a></i><br />
<br />
<br />
Source: <a href="http://ascorbate101.blogspot.com/2013/06/clinical-guide.html">http://ascorbate101.blogspot.com/2013/06/clinical-guide.html</a><br />
<br />
<br />
Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-77605832854118669092013-01-08T22:12:00.000-08:002013-01-08T22:13:02.270-08:00Vibrational Frequency List In 1992, <a href="http://www.tainio.com/">Bruce Tainio</a>
of Tainio Technology, an independent division of Eastern State
University in Cheny, Washington, built the first frequency monitor in
the world. Tainio has determined that the average frequency of the human
body during the daytime is 62-68 Hz. A healthy body frequency is 62-72
Hz . When the frequency drops, the immune system is compromised. Check
out these very interesting findings: <span class="fullpost"><br /><br /><b><span style="color: red;">Human Body:</span></b><br />Genius Brain Frequency 80-82 MHz<br />Brain Frequency Range 72-90 MHz<br />Normal Brain Frequency 72 MHz<br />Human Body 62-78 MHz<br />Human Body: from Neck up 72-78 MHz<br />Human Body: from Neck down 60-68 MHz Thyroid and Parathyroid glands are 62-68 MHz<br />Thymus Gland is 65-68 MHz<br />Heart is 67-70 MHz<br />Lungs are 58-65 MHz<br />Liver is 55-60 MHz<br />Pancreas is 60-80 MHz</span><br />
<span class="fullpost">Colds and Flu start at: 57-60 MHz<br />Disease starts at: 58 MHz<br />Candida overgrowth starts at: 55 MHz<br />Receptive to Epstein Barr at: 52 MHz<br />Receptive to Cancer at: 42 MHz<br />Death begins at: 25 MHz<br /><br /><b><span style="color: red;">Foods</span></b><br />(fresh foods and herbs can be higher if grown organically and eaten freshly picked):<br />Fresh Foods 20-27 Hz<br />Fresh Herbs 20-27 Hz<br />Dried Foods 15-22 Hz<br />Dried Herbs 15-22 Hz<br />Processed/Canned Food 0 HZ...(the majority of food we eat)</span><br />
<span class="fullpost"><br />According
to Dr. Royal R. Rife, every disease has a frequency. He found that
certain frequencies can prevent the development of disease and that
others would destroy disease. Substances with higher frequency will
destroy diseases of a lower frequency. The study of frequencies raises
an important question, concerning the frequencies of substances we eat,
breathe and absorb. Many pollutants lower healthy frequency.
Processed/canned food has a frequency of zero. Fresh produce has up to
15 Hz, dried herbs from 12 to 22 Hz and fresh herbs from 20 to 27 Hz. </span><br />
<span class="fullpost"></span><br />
<span class="fullpost">Essential
oils start at 52 Hz and go as high as 320 Hz, which is the frequency of
rose oil. Clinical research shows that therapeutic grade essential oils
have the highest frequency of any natural substance known to man,
creating an environment in which disease, bacteria, virus, fungus, etc.,
cannot live.<br /><br />American inventor Nikola Tesla (1856 – 1943), a
pioneer of electrical technology, said that if you could eliminate
certain outside frequencies that interfered in our bodies, we would have
greater resistance toward disease.<br /><br />Every essential oil has a
frequency and each of our organs and body parts have a frequency. The
frequency of an oil will attract a like frequency in the body. Lower
frequencies become a sponge for negative energy. The frequency is what
stays in the body to maintain the longer lasting effects of the oil. Low
frequencies make physical changes in the body. Middle frequencies make
emotional changes in the body. High frequencies make spiritual changes
in the body. Spiritual frequencies range from 92 to 360 Hz. (Bone
frequency is 38-43; neck and down frequency is 62-68). </span><br />
<br />
<br />
<div>
<span class="fullpost">Dr.
Robert O. Becker M.D, in his book, The Body Electric, who also explains
that a person's health can be determined by the frequency of the
person's body.</span><br />
<br />
<span class="fullpost">Another
doctor and scientist, whose research has been buried for some time but
has managed to resurface due to the work of avid supporters, is Dr Royal
Raymond Rife M.D, who developed a frequency generator in the late
1920’s. In brief, Rife successfully treated 1,000 patients diagnosed
with incurable cancer in the 1930’s. He was honoured with 14 awards and
an honorary doctorate. </span><br />
<br />
<span class="fullpost">After
the unsuccessful attempt by pharmaceutical companies to buy out his
research and equipment, his office was ransacked, his research paperwork
was stolen and the machine that healed all those 1,000 “incurable”
cancer patients was destroyed. </span></div>
<div>
<span class="fullpost"></span><br />
<span class="fullpost">In
1934, before this destruction occurred, the University of Southern
California appointed a Special Medical Research Committee to bring
terminal cancer patients from Pasadena County Hospital to Rife's San
Diego Laboratory and clinic for treatment. The team included doctors and
pathologists assigned to examine the patients - if still alive - in 90
days. After the 90 days of treatment, the Committee concluded that 86.5%
of the patients had been completely cured. The treatment was then
adjusted and the remaining 13.5% of the patients also responded within
the next four weeks. The total recovery rate using Rife's technology was
100%. <a href="http://www.rife.org/">http://www.rife.org/</a></span><br />
<br />
<span class="fullpost">What
Rife had developed was a 100% effective cure for many forms of cancer.
So why do we not know about this and why are there so many cancer
research foundations in existence? Put simply, it is due to the economic
motives of the orthodox medical community, which relies on funding for
cancer research - such funding often coming from pharmaceutical
companies - and whose fortunes would be damaged if a cure for cancer was
found. (That is, it’s OK to search for a cure but don’t really find
one!) This is a story that illustrates yet another grand attempt by the
mainstream medical community to control the lives - and deaths - of so
many millions of people today.<br /><br />“In every culture and in every
medical tradition before ours, healing was accomplished by moving
energy." - Albert Szent-Gyorgyi, Nobel Laureate in Medicine (1937) What
Rife proved is that every health disorder has a frequency, which in turn
responds (resonates) to a specific (optimal) frequency for its
dissolving/healing in the body.<br /><br />People who maintain their optimal
frequency, at least of their immune system, would prevent development
of symptoms and illnesses associated with the common cold. Of course, in
practise this does not work for most of us because, being human, we
experience stress and emotional challenges on a daily basis, which lower
our body frequency. Hence, we need to raise our body frequency
regularly/daily with the right substances that are compatible at the
cellular/energic level of our being, rather than wait until our body
frequency has dropped so low that it becomes a friendly host for
microscopic invaders.<br /><br /><b><span style="color: red;">How can we prove this?</span></b></span></div>
<div>
<span class="fullpost">According
to a report (Epidemiology, May 2001; 11:345-349) psychological stress -
particularly the chronic type that may accompany a personality with a
negative outlook - is a risk factor for contracting colds. An optimistic
outlook and outgoing personality seemed to protect individuals,
investigators found. The findings indicate that high levels of
psychological stress are closely associated with contracting the common
cold. While the common cold is rarely a serious health hazard, it is
responsible for about 30 million days of lost work in the U.S. alone
each year. To investigate whether stress increased the likelihood of
developing a cold, the researchers surveyed more than 1,100 Spanish
university staff and students at regular intervals over a one year
period. The study focused on different types of stress, including stress
from life events, perceived stress, having a generally negative
outlook, anxious or compulsive personality, compared with having a
positive outlook/attitude to life.</span></div>
<div>
<span class="fullpost"><br />
Individuals with a negative
outlook were at greatest risk of developing colds - regardless of their
intake of vitamin C and zinc or their smoking and drinking habits. The
next highest-risk individuals were those who believed that they were
under stress. These people were nearly three times as likely to develop a
cold, according to the report.<br /><b><span style="color: red;"><br />Why Should I Avoid An Antibiotic?</span></b><br />Colds
can be contracted as the result of contact with more than 200 different
viruses. However, among all of the cold viruses, the rhinovirus and the
coronavirus cause the majority of colds. Each time you have a cold, it
is caused by a distinct virus (e.g. adenovirus, rhinovirus,
parainfluenza virus, and coronavirus). Viruses are much smaller than
bacteria. They are tiny clusters of genetic material surrounded by a
protein ‘wrapper’. Medical science currently does not have any drugs
that can kill these viruses. Antibiotics, including penicillin, do not
have any effect on viruses. They are only used to treat secondary
bacterial infections that can further complicate the effects of a cold. </span></div>
<span class="fullpost"></span><br />
<span class="fullpost"><div>
<br />
<span style="color: red;"><b>How Do We Actually Contract the Cold?</b></span><br />
The
most common source of infection is not from coughing or sneezing, or
walking barefoot in the rain, but from hand-to-hand contact. That is
why, when you have a cold, washing your hands frequently is very
important. The likelihood of contracting the cold virus increases,
however, if one is overtired and physically exhausted. Most
uncomplicated colds last eight to nine days; about 25% last two weeks;
and 5 -10% last three weeks.As long as one’s temperature remains below
38.8 degrees Celsius, there is no need to lower it. Cold viruses do not
reproduce at higher body temperatures. In fact, a slight fever should
help us get rid of the virus quicker and feel better much sooner. It is
our body’s own way of ridding itself of toxins.Why are Aspirin and
Tylenol counterproductive?A study (J Infect Dis, Dec 1990;
162(6):1277-82) showed that people who take aspirin and Tylenol
(acetaminophen) suppress their body's ability to produce antibodies that
destroy the cold virus. This actually causes the body to take longer to
fight the cold and it accounts for any secondary infections and
post-nasal drip.<br />
<br />
<b><span style="color: red;">What Can We Do to Avoid Common Cold?</span></b></div>
<div>
<b><span style="color: red;"></span></b>While
orthodox medicine does not have the answer for colds and ‘flu, nature
does - and it comes in the form of pure organic unadulterated
Therapeutic Essential Oils. Why? Because they are made up of very high
frequency molecules (ranging from 52MHz to 320MHz) and contain nature’s
wisdom and power to raise the body’s frequency and to assist our immune
system to fight viral invasions. For greater clarity, organic
Therapeutic Essential Oils are not the same as everyday aromatherapy
oils, which are produced for fragrant and other purposes. </div>
</span><br />
<div>
</div>
<div class="post-footer">
<br />
COMMENT: I am a neurofeedback therapist and have found that on the first day of a
cold (early symptoms are sore throat and achy body) that if I uptrain
beta (15-18hz) at F3 (10-20 electrode placement) left prefrontal lobe -
the symptoms dissipate after 10-15 mins. In some peculiar way the immune
system is kicked into action and energy is restored. I am thankful to
have found your blog!<br />
<br />
Lisa T<br />
San Diego<br />
<br />
Source: <a href="http://theashbulletin.blogspot.com/2013/01/vibrational-frequency-list.html" target="_blank">The ASH Bulletin</a></div>
Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-43406711527969577272012-10-12T14:48:00.003-07:002012-10-12T14:48:22.975-07:00RATH/PAULING U.S. PATENT # 5278189<b><font size="3"><center>RATH/PAULING U.S. PATENT # 5278189</center></b></font> <div style="MARGIN-LEFT: 10px; MARGIN-RIGHT: 10px; MARGIN-TOP: 10px"><font face="Verdana, Arial, Helvetica, sans-serif" size="2">
<h4>
Prevention and treatment of occlusive cardiovascular disease with
ascorbate and substances that inhibit the binding of lipoprotein (A)
</h4>
<hr>
<h3>PATN Patent Bibliographic Information</h3>
<pre>WKU Patent Number: 05278189
SRC Series Code: 7
APN Application Number: 5575168
APT Application Type: 1
ART Art Unit: 125
APD Application Filing Date: 19900724
TTL Title of Invention: Prevention and treatment of occlusive cardiovascular
disease with ascorbate and substances that
inhibit the binding of lipoprotein (A)
ISD Issue Date: 19940111
NCL Number of Claims: 15
ECL Exemplary Claim Number: 1
EXA Assistant Examiner: Henley, III; Raymond J.
EXP Primary Examiner: Waddell; Frederick E.
NDR Number of Drawings Sheets: 5
NFG Number of Figures: 6
</pre>
<h3>INVT Inventor Information</h3>
<pre>NAM Inventor Name: Rath; Matthias W.
STR Inventor Street: Eberhardstrasse 12
CTY Inventor City: 7141 Kirchberg/Murr
CNT Inventor Country: DEX
INVT Inventor Information
NAM Inventor Name: Pauling; Linus C.
STR Inventor Street: 15 Salmon Creek
CTY Inventor City: Big Sur
STA Inventor State: CA
ZIP Inventor Zip Code: 93920
</pre>
<h3>
RLAP Related U.S. Application Data
</h3>
<pre>COD Parent Code: 72
APN Application Number: 533129
APD Application Filing Date: 19900604
PSC Parent Status Code: 03
</pre>
<h3>
CLAS Classification
</h3>
<pre>OCL Original U.S. Classification: 514561
XCL Cross Reference Classification: 514356
XCL Cross Reference Classification: 514474
XCL Cross Reference Classification: 514824
EDF International Classification Edition Field: 5
ICL International Classification: A61K 31195
ICL International Classification: A61K 3134
ICL International Classification: A61K 3144
FSC Field of Search Class: 514
FSS Field of Search Subclass: 474;561;562;564;567;824
;356
</pre>
<h3>
UREF U.S. Patent Reference
</h3>
<pre>PNO Patent Number: 3956504
ISD Issue Date: 19760500
NAM Patentee Name: Sawyer
OCL Original U.S. Classification: 514567
</pre>
<h3>
U.S. Patent References
</h3>
<h4>
UREF U.S. Patent Reference
</h4>
<pre>PNO Patent Number: 4424232
ISD Issue Date: 19840100
NAM Patentee Name: Parkinson
OCL Original U.S. Classification: 514474
</pre>
<h4>
UREF U.S. Patent Reference
</h4>
<pre>PNO Patent Number: 4600582
ISD Issue Date: 19860700
NAM Patentee Name: Stevens et al.
OCL Original U.S. Classification: 514561
</pre>
<h4>
UREF U.S. Patent Reference
</h4>
<pre>PNO Patent Number: 4954521
ISD Issue Date: 19900900
NAM Patentee Name: Sawyer et al.
OCL Original U.S. Classification: 514474
</pre>
<h4>
FREF Foreign Reference
</h4>
<pre>PNO Patent Number: 60-4611
ISD Issue Date: 19850000
CNT Foreign Reference Country Code: JPX
</pre>
<h4>
FREF Foreign Reference
</h4>
<pre>PNO Patent Number: 60-78560
ISD Issue Date: 19850000
CNT Foreign Reference Country Code: JPX
</pre>
<h4>
FREF Foreign Reference
</h4>
<pre>PNO Patent Number: 60-87221
ISD Issue Date: 19850000
CNT Foreign Reference Country Code: JPX
</pre>
<h4>
OREF Other Reference
</h4>
<p>
Chemical Abstracts 77(13):86318 (1972).
</p><p>
Vitamin C in Health and Disease, Basu et al., AVI Publishing Co., Inc.
(1982) pp. 95-101.
</p><p>
Martindale, The Extra Pharmacopoeia, 28th edition (1982) p. 56, "Lysine
Hydrochloride".
</p><p>
The Nutrition Desk Reference, Garrison et al, Keats Publishing Inc. (1985)
pp. 172-177.
</p><p>
Rath, M. & L. Pauling, "Solution of the puzzle of human cardiovascular
disease: Its primary cause is ascorbate deficinecy leading to the
deposition of lipoprotein(a) and fibrinogen/fibrin in the vascular wall,"
J. Orthomolecular Med. (In Press 1991).
</p><p>
Markwardt, F. & H. P. Klocking, "Chemical control of hyperfibrinolytic
states by synthetic inhibitors of fibrinolytic enzymes," Biomed. Biochim.
Acta 42:725-730 (1983).
</p><p>
Werb, Z. et al., "Endogenous activation of latent collagenase by rheumatoid
synovial cells," New England J. Med. 296(18):1017-1023 (1977).
</p><p>
Knox, E. G., "Ischaemic-heart-disease mortality and dietary intake of
calcium," Lancet, i, pp. 1465-1467, Jun. 30, 1973.
</p><p>
Berg, K. "A new serum type system in man--The LP system," Acta Path.
59:369-382 (1963).
</p><p>
McLean, J. et al., "cDNA sequence of human apolipoprotein(a) is homologous
to plasminogen," Nature 300:132-137 (1987).
</p><p>
Salonen, E-M, et al., "Lipoprotein(a) binds to fibronectin and has serine
proteinase activity capable of cleaving it," EMBO J. 8(13):4035-4040
(1989.
</p><p>
Harpel, P.C. et al., "Plasmin catalyzes binding of lipoprotein(a) to
immobilized fibrinogen and fibrin," Proc. Natl. Acad. Sci. USA
86:3847-3851 (1989).
</p><p>
Gonzalez-Gronow, M. et al., "Further characterization of the cellular
plasminogen biding site: Evidence that Plasminogen 2 and Lipoprotein a
compete for the same site," Biochemistry 28:2374-2377 (1989).
</p><p>
Hajjar, K. A. et al., "Lipoprotein(a) modulation of endothelial cell
surface fibrinolysis and its potential role in atherosclerosis," Nature
339:303-305 (1989).
</p><p>
Armstrong, V. W. et al., "The association between serum Lp(a)
concentrations and angiographically assessed coronary atherosclerosis";
Atheroscloerosis 62:249-257 (1986).
</p><p>
Dahlen, G. H. et al., "Association of levels of lipoprotein Lp(a), plasma
lipids, and other lipoproteins with coronary artery disease documented by
angiography," Circulation 74(4): 758-765 (1986).
</p><p>
Miles, L. A. et al., "A potential basis for the thrombotic risks associated
with Lipoprotein (a)," Nature 339:301-302 (1989).
</p><p>
Zenker, G. et al., "Lipoprotein(a) as a strong indicator for
cerebrovascular disease," Stroke 17(5)942-945 (1986).
</p><p>
Zechner, R. et al., "Fluctuations of plasma Lipoprotein-A concentrations
during pregnancy and post partum," Metabolism 35(4):333-336 (1986).
</p><p>
Hoff, H. et al., "Serum Lp(a) level as a predictor of vein graft stenosis
after coronary artery bypass surgery in patients," Circulation
77(6):1238-1244 (1988).
</p><p>
Rath, M. et al., "Detection and quantification of Lipoprotein(a) in the
arterial wall of 107 coronary bypass patients," Arteriosclerosis
9(5):579-592 (1989).
</p><p>
Cushing, G. L. et al., "Quantitation and localization of Apolipoproteins
[a] and B in Coronary artery bypass vein grafts resected at re-operation,"
Arteriosclerosis 9(5):593-603 (1989).
</p><p>
Bruckert, E. et al., "Increased serum levels of Lipoprotein(a) in diabetes
mellitus and their reduction with glycemic control," JAMA 263(1):35-36
(1990).
</p><p>
Blumberg, B., et al., "A human lipoprotein polymorphism," J. Clin. Invest.
41:1936-1944 (1962).
</p><p>
Eaton, D. L., et al., "Partial amoni acid sequence of apolipoprotein(a)
shows that it is homologous to plasminogen," Proc. Natl. Acad. Sci. USA,
84:3224-3228 (1987).
</p><p>
Wright, L. C. et al., "Elevated apolipoprotein(a) levels in cancer
patients," Int. J. Cancer 43:241-244 (1989).
</p><p>
Som, S. et al., "Ascorbic acid metabolism in diabetes mellitus," Metabolism
30:572-577 (1981).
</p><p>
Maeda, S. et al., "Transient changes in serum lipoprotein(a) as an acute
phase protein," Atherosclerosis 78:145-150 (1989).
</p><p>
Kapeghian, J. C. et al., "The effects of glucose on ascorbic acid uptake in
heart, endothelial cells: Possible pathogenesis of diabetic angiopathies,"
Life Sci. 34:577 (1984).
</p><p>
Tomlinson, J. E. et al., "Rhesus monkey apolipoprotein(a)," J. Biol. Chem.
264:5957-5965 (1989).
</p><p>
Ginter, E. et al., "The effect of chronic hypovitaminosis C on the
metabolism of cholesterol and athergenesis in guinea pigs," J.
Atherosclerosis Res. 10:341-352 (1969).
</p><p>
</p><h3>
LREP Legal Information
</h3>
<pre>FRM Legal Firm: Limbach & Limbach
</pre>
<h3>
ABST Abstract
</h3>
A method is provided for prevention and treatment of cardiovascular
disease, such as atherosclerosis, by administering therapeutically
effective dosages of a drug comprised of ascorbate, lipoprotein(a) binding
inhibitors, and antioxidants.
<h3>
PARN Parent Case Text
</h3>
This application is a continuation-in-part of application Ser. No.
07/533,129, filed Jun. 4, 1990.
<h3>
BSUM Brief Summary
</h3>
<h4>
TECHNICAL FIELD
</h4>
The present invention relates generally to the prevention and treatment of
cardiovascular disease and more particularly to methods and compounds that
inhibit the binding of lipoprotein (a) to components of the arterial wall.
<h4>
BACKGROUND OF THE INVENTION
</h4>
Lipoprotein(a) ("Lp(a)") was first identified by Blumberg, B. S., et al.
(1962) J. Clin. Invest. 41: 1936-1944 , and Berg, K. (1963) Acta Pathol.
59: 369-382. The structure of Lp(a) resembles that of low-density
lipoprotein ("LDL") in that both share a lipid apoprotein composition,
mainly apolipoprotein B-100 ("apo B"), the ligand by which LDL binds to
the LDL receptors present on the interior surfaces of arterial walls. The
unique feature of Lp(a) is an additional glycoprotein, designated
apoprotein(a), apo(a), which is linked to apo B by disulfide groups. The
cDNA sequence of apo(a) shows a striking homology to plasminogen, with
multiple repeats of kringle 4, one kringle 5, and a protease domain. The
isoforms of apo(a) vary in the range of 300 to 800 kDa and differ mainly
in their genetically determined number of kringle 4 structures. McLean, J.
W., et al. (1987) Nature 300: 132-137. Apo(a) has no plasmin-like protease
activity. Eaton, D. L., et al., (1987) Proc. Natl Acad. Sci. USA, 84:
3224-3228. Serine protease activity, however, has been demonstrated.
Salonen, E., et al. (1989) EMBO J. 8: 4035-4040. Like plasminogen, Lp(a)
has been shown to bind to lysine-sepharose, immobilized fibrin and
fibrinogen, and the plasminogen receptor on endothelial cells. Harpel,
P.C., et al. (1989) Proc. Natl. Acad. Sci. USA 86:3847-3851;
Gonzalez-Gronow, M., et al. (1989) Biochemistry 28: 2374-2377; Miles, L.
et al. (1989) Nature 339: 301-302; Hajjar, K. A., et al. (1989) Nature
339: 303-305. Furthermore, Lp(a) has been demonstrated to bind to other
components of the arterial wall like fibronectin and glycosaminoglycans.
The nature of these bindings, however, is poorly understood.
<p>
Essentially all human blood contains lipoprotein(a); however, there can a
thousand-fold range in its plasma concentration between individuals. High
levels of Lp(a) are associated with a high incidence of cardiovascular
disease. Armstrong, V. W., et al. (1986) Atherosclerosis 62: 249-257;
Dahlen, G., et al. (1986) Circulation 74: 758-765; Miles, L. A., et al.
(1989) Nature 339: 301-302; Zenker, G., et al. (1986). Stroke 17: 942-945
(The term occlusive cardiovascular disease will be used hereafter as
including all pathological states leading to a narrowing and/or occlusion
of blood vessels throughout the body, but particularly atherosclerosis,
thrombosis and other related pathological states, especially as occurs in
the arteries of the heart muscle and the brain.)
</p><p>
For some time, general medical practice has focused on the role of LDL, th
e
so called "bad cholesterol," in occlusive cardiovascular disease. A great
many studies have been published ostensibly linking occlusive
cardiovascular disease with elevated levels of LDL. As a result, most
therapies for the treatment and prevention of arteriosclerosis rely on
drugs and methods for the reduction of serum levels of LDL's. Such
therapies have had mixed results. The efficacy of such approaches to the
problem of occlusive cardiovascular disease continues to be major source
of debate.
</p><p>
There exists therefore a need for a drug therapy for reducing the binding
of Lp(a) to vessel walls, for reducing the overall level of Lp(a) in the
circulatory system and for promoting the release of existing deposits of
Lp(a) on vessel walls.
</p><h4>
SUMMARY OF THE INVENTION
</h4>
The foregoing needs in the treatment and prevention of cardiovascular
disease are met by the methods and compositions of the present invention.
<p>
A method is provided for the treatment of occlusive cardiovascular disease
,
comprising the step of administering to a subject an effective amount of
ascorbate and one or more binding inhibitors, as a mixture or as a
compound comprising ascorbate covalently linked with binding inhibitors,
which inhibit the binding of Lp(a) to blood vessel walls, such as arterial
walls. This effect may also be obtained by administering an effective
amount of one or more inhibitors, without ascorbate. The term binding
inhibitor throughout the specification and claims is intended to include
all substances that have an affinity for the lysine binding site present
on the interior walls of blood vessels, particularly arteries, the site of
Lp(a) binding. Most of these substances compete with plasmin for the
lysine binding site and some of these compounds, in high doses, are in
clinical use for the treatment of hyperfibrinolytic states.
</p><p>
A method is further provided for the prevention of atherosclerosis
comprising the step of administering to a subject an effective amount of
ascorbate and one or more binding inhibitors as previously discussed but
further comprising one or more antioxidants. The term antioxidant
throughout the specification and the claims is intended to exclude
ascorbate which has as one of its chemical properties a potent antioxidant
effect.
</p><p>
It is thus an object of the invention to provide a method for treatment of
occlusive cardiovascular disease by administering to a subject an
effective amount of ascorbate and one or more binding inhibitors, or an
effective amount of one or a mixture of binding inhibitors.
</p><p>
It is another object of the invention to provide a method for preventing o
f
occlusive cardiovascular disease, by administering to a subject an amount
of ascorbate effective to lower the amount of Lp(a) in the plasma of the
subject.
</p><p>
Yet another object of the present invention is to provide a method for
prevention of cardiovascular disease by administering to a subject an
effective amount of ascorbate and one or more binding inhibitors, or an
effective amount of one or more binding inhibitors.
</p><p>
A further object of the present invention is to provide a pharmaceutically
acceptable agent for the treatment of occlusive cardiovascular disease.
</p><p>
Still another object of the present invention is to provide a
pharmaceutically acceptable agent for the prevention of cardiovascular
disease.
</p><p>
These and other objects will be more readily understood upon consideration
of the following detailed descriptions of embodiments of the invention and
the drawings.
</p><h3>
DRWD Drawing Description
</h3>
<h4>
BRIEF DESCRIPTION OF THE DRAWINGS
</h4>
FIG. 1 is an immunoblot of the plasma of guinea pigs form from the test
described in Example 1.
<p>
FIG. 2A a photograph of the aorta of a guinea pig receiving an adequate
amount of ascorbate from the test diet in Example 1.
</p><p>
FIG. 2B is a photograph of an aorta of a guinea pig receiving a
hypoascorbic diet after three weeks from the test diet in Example 1.
</p><p>
FIG. 3 is an immunoblot of plasma and tissue of guinea pigs from the test
shown in Example 2.
</p><p>
FIG. 4 shows the potential mechanism of binding inhibitors in the therapy
for atherosclerosis.
</p><p>
FIG. 5 show the potential mechanism of ascorbate in the binding of Lp(a) t
o
the arterial wall.
</p><h3>
DETD Detail Description
</h3>
<h4>
DETAILED DESCRIPTION OF THE INVENTION
</h4>
Our invention is based in part on our discovery that animals which have
lost the ability to produce ascorbate, such as higher primates and guinea
pigs, uniformly produce Lp(a). Most animals which possess the ability to
synthesize ascorbate generally do not produce Lp(a). Further, we have
found that ascorbate deficiency in humans and guinea pigs tends to raise
Lp(a) levels and causes atherosclerosis by the deposition of Lp(a) in the
arterial wall, from which we conclude that ascorbate administration lowers
plasma Lp(a) levels.
<p>
We have also discovered that substances that inhibit the binding of Lp(a)
to components of the arterial wall, particularly to fibrinogen, fibrin and
fibrin degradation products herein identified as binding inhibitors, such
as lysine or .epsilon.-aminocaproic acid used alone or in combination with
ascorbate, cause release of Lp(a) from the arterial wall. Thus, ascorbate
and such binding inhibitors are not only useful for the prevention of
occlusive cardiovascular disease, but also for the treatment of such
disease. The present invention, then, provides methods and pharmaceutical
agents for the both the treatment and prevention of occlusive
cardiovascular disease in vivo.
</p><h4>
GENERAL APPLICATIONS
</h4>
The present invention provides a method and pharmaceutical agent for the
treatment and prevention of occlusive cardiovascular disease generally, by
administering to a subject an effective amount of ascorbate and one or
more binding inhibitors. Throughout the specification and claims, the term
binding inhibitor is intended to cover any substance which has as at least
one of its chemical properties the ability to inhibit the binding of Lp(a)
to blood vessel wall components, particularly to fibrin or fibrinogen. As
used herein, the term "ascorbate" includes any pharmaceutically acceptable
salt of ascorbate, including sodium ascorbate, as well as ascorbic acid
itself. Binding inhibitors include, but are not limited to
.epsilon.-aminocaproic acid, lysine, tranexamic acid
(4-aminomethylcyclohexane carboxylic acid), p-aminomethylbenzoic acid,
p-benzylamine sulfuric acid, o-N-acetyl-lysine-methyl ester, PROBUCOL (a
compound comprised of 2 butyl hydroxy tocopherol groups linked together by
a disulphide group), Aprotinin, trans-4-aminomethylcyclohexanecarboxylic
acid (AMCA), and benzamidine derivatives such as amidinophenylpyruvic acid
(APPA) and 1-naphthyl-(1)-3-(6-amidinonaphthyl-(2))-propanone-1 HCl
(NANP). An effective amount of a binding inhibitor or a mixture of binding
inhibitors may also be used, without ascorbate. Other substances used in
the treatment of occlusive cardiovascular disease may be co-administered,
including antioxidants, such as tocopherol, carotene and related
substances; vitamins; provitamins; trace elements; lipid-lowering drugs,
such as hydroxy-methyl-glutaryl coenzyme A reductase inhibitors, nicotinic
acid, fibrates, bile acid sequestrants; and mixtures of any two or more of
these substances.
<p>
Although ascorbate can be used alone or in varying combinations with one o
r
more representative constituents of the above classes of compounds, we
prefer when treating a pre-existing cardiovascular condition to combine
ascorbate with at least one each of the binding inhibitors, antioxidants
and lipid lowering drugs elements in the dosages (per kilogram of body
weight per day (Kg BW/d)) provided in Table 1. It should be noted that
Table 1 provides differing concentration ranges of each constituent,
depending upon whether the agent is to be administered orally or
parenterally. The variance in dosages is reflective of variation in
disease severity. It will be realized therefore that if the subject has
been diagnosed for advanced stages of atherosclerosis,
</p><p>
dosages at the higher end of this range can be utilized. However, if only
prevention of an atherosclerosis condition is the object, dosages at the
lower end of this range can be utilized.
</p><p>
As an alternative, a pharmaceutical agent identical to the one just
described, but omitting ascorbate, may be employed.
</p><p>
Where ascorbate and binding inhibitors are utilized in the same agent, the
y
may simply be mixed or may be chemically combined using synthesis methods
well known in the art, such as compounds in which ascorbate and the
inhibitor are covalently linked, or form ionically bound salts. For
example, ascorbate may be bound covalently to lysine, other amino acids,
or .epsilon.-aminocaproic acid by ester linkages. Ascorbyl
.epsilon.-aminocaproate is such an example. In this form the ascorbate
moiety may be particularly effective in preventing undesirable lipid
peroxidation.
</p><p>
In the case of oral administration, a pharmaceutically acceptable and
otherwise inert carrier may be employed. Thus, when administered orally,
the active ingredients may be administered in tablet form. The tablet may
contain a binder such as tragacanth, corn starch or gelatin; a
disintegrating agent, such as alginic acid, and/or a lubricant such as
magnesium stearate. If administration in liquid form is desired,
sweetening and/or flavoring agents may be used. If administration is by
parenteral injection, in isotonic saline, a phosphate buffered solution or
the like, may be used as a pharmaceutically acceptable carrier.
</p><p>
The advisability of using binding inhibitors in treating occlusive
cardiovascular disease will depend to some extent on the subject's general
health, particularly with regard to hyperfibrinolytic conditions. Most
binding inhibitors (except lysine) are used clinically to treat such
conditions. As a result, monitoring of the subject's coagulation and
fibrinolytic sysem is recommended before and during treatment for
occlusive cardiovascular disease. Long-term administration of binding
inhibitors will require formulations in which the dosages of binding
inhibitors are in the lower ranges of the dosages given in Table 1.
</p><p>
Prevention, as contrasted with treatment, of cardiovascular disease may be
accomplished by oral or parenteral administration of ascorbate alone.
Table 1 gives a range of ascorbate concentrations sufficient to lower the
serum Lp(a) concentration.
</p><p>
Preferably the prevention of the occlusive cardiovascular disease accordin
g
to the invention is accomplished by use of a physical mixture of ascorbate
and one or more binding inhibitors, or by use of a compound comprising
covalently linked ascorbate with one or more of the binding inhibitors,
which inhibit binding of Lp(a) to the arterial wall. A binding inhibitor
or mixture of binding inhibitors may also be administered without
ascorbate to prevent Lp(a)-associated occlusive cardiovascular disease.
</p><p>
To optimize the therapeutic effect of the release of Lp(a) from the blood
vessel walls, the ascorbate and the binding inhibitors described above may
be separately administered. Further optimization of therapeutic effect can
be gained by using a time release composition to achieve relatively
constant serum concentrations of the agent through time.
</p><h4>
TBL TABLE 1
</h4>
<pre> ______________________________________
DOSAGES OF COMPONENTS IN THE DRUG
COMPOSITIONS OF THE PRESENT INVENTION
Oral Parenteral
Administration
Administration
______________________________________
Ascorbate: 5 mg-2500 mg/kg
25 mg-2500 mg/kg
bw/d bw/d
Binding inhibitors:
EACA 5 mg-500 mg/kg
same
bw/d
Tranexamic Acid
1 mg-100 mg/kg
same
bw/d
Para-aminomethyl
1 mg-30 mg/kg same
benzoic acid bw/d
Lysine 5-500 mg/kg bw/d
same
Antioxidants:
Tocopherol 0,1 IU-20 IU/kg
same
bw/d
Carotene 100 IU-1000 IU/kg
same
bw/d
Lipid
Lowering Drugs:
Nicotinic Acid
1 mg-300 mg/kg
bw/d
HMG-CoA 0.1-10 mg/kg bw/d
Fibrates 0.1-20 mg/kg bw/d
Probucol 0.1-20 mg/kg bw/d
Bile Acid Sequestrants
10-400 mg/kg bw/d
______________________________________
</pre>
<h4>
TBL TABLE 2
</h4>
<pre> ______________________________________
CONCENTRATION OF COMPONENTS IN THE
SOLUTION OF THE PRESENT INVENTION
______________________________________
Ascorbate 50-5000 mg/l
Binding inhibitors
EACA 2-2000 mg/l
Tranexamic Acid 1-300 mg/l
Para-aminomethyl 1-200 mg/l
benzoic acid
Lysine 10-5000 mg/l
Antioxidants
Tocopherol 1-1000 mg/l
Carotene 0.1-100 mg/l
______________________________________
</pre>
<h4>
EXPERIMENTAL
</h4>
Having disclosed the preferred embodiment of the present invention, the
following examples are provided by way of illustration only and are not
intended to limit the invention in any way.
<p>
</p><h4>
EXAMPLE 1
</h4>
Because of its metabolic similarity to man, with resepct to the metabolism
of ascorbate and Lp(a), the guinea pig was used in this example.
<p>
No study has been previously reported in the guinea pig to identify the
lopoprotein involved as risk factors in plasma and as constituents of the
atherosclerotic plaque.
</p><p>
Three female Gartly guinea pigs with an average weight of 800 g and an
approximate age of 1 year wer stuided. One animal received an extreme
hypoascorbic diet with 1 mg ascorbate/kg body weight/d. Another animal
received 4 mg/kg BW/d. The third animal served as a control receiving 40
mg ascorbate/kg/BW/d)
</p><p>
Blood was drawn by heart puncture from the anesthetized animals and
collected into EDTA containing tubes at the beginning, after 10 days, and
after 3 weeks, when the animals were sacrificed. Plasma was stored at
- -80.degree. C. until analyzed. Lp(a) was detected in the plasma of the
guinea pigs by use of SDS-polyacrylamide gels according to Neville (J.
Biol. Chem., 246, 6328-6334 (1971)) followed by Western blotting
(Beisiegel, et al., J. Biol. Chem., 257, 13150-13156 (1982)). 40 .mu.l of
plasma and 20 mg of arterial wall homogenate were applied in delipidated
form per lane of the gel. The immunodetection of apo(a) was performed
using a polyclonal anti-human apo(a) antibody (Immuno, Vienna, Austria)
followed by a rabbit anti-sheep antibody (Sigma) and the gold-conjugated
goat anti-rabbit anti-body with subsequent silver enhancement (Bio-Rad).
The determinations of cholesterol and triglycerides were done at
California Veterinary Diagnostics (Sacramento) using the enzyme assay of
Boehringer Mannheim. Plasma ascorbate was determined by the
dinitrophenylhydrazine method (Schaffer, et al., J. Biol. Chem., 212, 59
(1955)).
</p><p>
Vitamin C deficiency in the diet led to an increase of Lp(a) in the plasma
of the guinea pig indicated by a clear band in the immunoblot of the
plasma after 10 and 20 days of a hypoascorbic diet (FIG. 1). At necropsy
the animals were anesthetized with metophase and were exsanguinated.
Aorta, heart and various other organs were taken for biochemical and
histological analysis. The aorta was excised, the adventitial fat was
carefully removed, and the vessel was opened longitudinally. Subsequently
the aorta was placed on a dark metric paper and a color slide was taken.
The picture was projected and thereby magnified by an approximate factor
10. The circumference of the ascending aorta, the aortic arch and thoracic
aorta as well as the atherosclerotic lesions in this area were marked and
measured with a digitalized planimetry system. The degree of
atherosclerosis was expressed by the ratio of plaque area to the total
aortic area defined. The difference in the 3 one-year old animals of the
experiment was significant and pronounced lesions were observed in the
ascending aorta and the arch of the vitamin C deficient animal (FIG. 2B).
</p><h4>
EXAMPLE 2
</h4>
To confirm the data obtained in Example 1, a second guinea pig experiment
was conducted, using 33 male animals with a mean weight of 550 g and an
approximate age of 5 months. One group of 8 animals served as a control
and received 40 mg ascorbate/kg BW/d (group A). To induce hypoascorbemia
16 animals were fed 2 mg ascorbate/kd/d (group B). Group A and half of the
animals of group B (progression sub-group) were sacrificed after 5 weeks
as described above. Half of group B was kept for 2 more weeks, receiving
daily intraperitoneal injection of 1.3 g sodium ascorbate/Kg BW/d as a
daily intra peritoneal injection with the intention to reduce the extent
of atherosclerosis lesions. After this period these animals also were
sacrificed.
<p>
Plasma ascorbate levels were negatively correlated with the degree of the
atherosclerotic lesion. Total cholesterol levels increased significantly
during ascorbic acid deficiency (Table 3).
</p><p>
The aortas of the guinea pigs receiving a sufficient amount of ascorbate
were essentially plaque free, with minimal thickening of the intima in the
ascending region. In contrast, the ascorbate-deficient animals exhibited
fatty streak-like lesions, covering most parts of the ascending aorta and
the aortic arch. In most cases the branching regions of the intercostal
arteries of the aorta exhibited similar lipid deposits. The difference in
the precentage of lesion area between the control animals and the
hypoascorbic diet animals was 25% deposition of lipids and liporpoteins in
the arterial wall.
</p><h4>
TBL TABLE 3
</h4>
<pre> ______________________________________
MEAN PLASMA
PARAMETERS OF THE DIFFERENT GROUPS
IN RELATION TO THE AREA OF AORTIC LESIONS
Regression
Scurvy (after
Control (progress)
Scurvy)
______________________________________
Plasma 39 54 33
Chloesterol
(mg/dl)
Total Plasma
5.03 3.01 20.64
Ascorbic
Acid .mu.g/ml
Atheroscl. -- 25 19
Lesion
(Percent of
Aorta Thorac.
Surface)
______________________________________
</pre>
<h4>
EXAMPLE 3
</h4>
Human arterial wall was obtained post mortem from the aorta ascendens. The
tissue showed homogeneous intimal thickening (early atherosclerotic
lesion). It was cut into pieces, with 100 mg of the cut up tissue
homogenized in a glass potter for a 1 minute in 2.5 ml of the following
solutions:
<p>
</p><pre>
TBL ______________________________________
PBS (Dulbeco) + 50 mg/ml
NaAscorbate
PBS + EACS 50 mg/ml
PBS + Tranexamic Acid
50 mg/ml
PBS + NaAscorbate +
50 mg/ml
Tranexamic Acid
______________________________________
</pre>
<p>
Results of this treatment are given in Table 4 and show that, compared to
the control solution, a considerable amount of Lp(a) was released from the
interior arterial wall.
</p><p>
</p><h4>
TBL TABLE 4
</h4>
<pre> __________________________________________________________________________
Lp(a) RELEASED FROM HUMAN AORTA
IN RELATION TO SPECIFIC BINDING INHIBITORS
##STR1##
__________________________________________________________________________
</pre>
By now it is apparent that the methods and compositions of the present
invention meet longstanding meeds in the field of prevention and treatment
of occlusive cardiovascular disease. Although preferred embodiments and
examples have been disclosed, it is understood that the invention is in no
way limited by them, but rather is defined by the claims that follow and
equivalents thereof.
<p>
</p><h3>
CLMS Claims
</h3>
STM Claim Statement: What is claimed is:
<h4>
NUM Claim Number: 1.
</h4>
<ul>
<li>
1. A pharmaceutical composition consisting essentially of ascorbate,
traexamic acid, lysine and nicotinic acid said ingredients in an amount
effective to treat Lp (a)-associated occlusive cardiovascular disease.
</li><li>
NUM Claim Number: 2.
2. A method of treatment of occlusive cardiovascular disease comprising th
e
step of administering to a subject a therapeutic composition comprising
ascorbate and tranexamic acid in an amount sufficient to decrease the
binding of liproprotein (a) to blood vessel walls.
</li><li>
NUM Claim Number: 3.
3. A method according to claim 2 wherein said ascorbate is selected from
the group consisting of pharmaceutically acceptable ascorbate salts,
ascorbic acid and mixtures thereof.
</li><li>
NUM Claim Number: 4.
4. A method for treatment of occlusive cardiovascular disease comprising
the step of administering to a subject a therapeutic composition
comprising tranexamic acid in an amount sufficient to decrease the binding
of lipoprotein(a) to blood vessel walls.
</li><li>
NUM Claim Number: 5.
5. A method according to any one of the claims 2, 3 or 4 wherein occlusive
cardiovascular disease comprises atherosclerosis and thrombosis and said
vessel walls comprise arterial walls.
</li><li>
NUM Claim Number: 6.
6. A method according to any one of the claims 2, 3 or 4 wherein said
therapeutic composition is administered to a subject at risk of developing
and in need of preventing for Lp (a)-associated occlusive cardiovascular
disease in an amount of effective to inhibit binding of liproprotein(a) to
blood vessel walls.
</li><li>
NUM Claim Number: 7.
7. A method according to any one of the claims 2, 3 or 4 wherein said
therapeutic composition is administered in an amount effective to release
at least some lipoprotein(a) bound to blood vessels.
</li><li>
NUM Claim Number: 8.
8. A method according to any one of the claims 2, 3 or 4 wherein said
therapeutic composition is administered in an amount effective to reduce
concentrations of lipoprotein(a) in blood serum.
</li><li>
NUM Claim Number: 9.
9. A method for prevention of cardiovascular disease comprising the step o
f
administering to a subject at risk of developing and in need of prevention
for Lp (a)-associated occlusive cardiovascular disease a therapeutic
composition comprising ascorbate and tranexamic acid in an amount
sufficient to decrease binding of liproprotein(a) to blood vessel walls.
</li><li>
NUM Claim Number: 10.
10. A method according to claim 9 wherein said ascorbate is selected from
the group consisting of pharmaceutically acceptable salts of ascorbate,
ascorbic acid and mixtures thereof.
</li><li>
NUM Claim Number: 11.
11. A method of prevention of occlusive cardiovascular disease comprising
the step of administering to a subject at risk of developing and in need
of prevention for Lp (a)-associated occlusive cardiovascular disease a
therapeutic composition comprising tranexamic acid in an amount sufficient
to decrease binding of lipoprotein(a) to blood vessel walls.
</li><li>
NUM Claim Number: 12.
12. A method according to any one of claims 9, 10 or 11 wherein said
therapeutic composition is administered in an amount effective to inhibit
binding of lipoprotein(a) to the blood vessel walls.
</li><li>
NUM Claim Number: 13.
13. A method according to any one of claims 9, 10, 11, or 12 wherein said
therapeutic composition is administered in an amount effective to reduce
concentrations of lipoprotein(a) in blood serum.
</li><li>
NUM Claim Number: 14.
14. A method according to any one of claims 2, 3, 4 or 9 wherein the
administration is oral.
</li><li>
NUM Claim Number: 15.
15. A method according to any one of claims 2, 3, 4 or 9 wherein
administration is by parenteral application.
</li></ul>
<p>
Source: <a href="http://www.advancedhealthplan.com/paulingpatent.html" target="_blank"><i> Advanced Health Plan</i></a><br></p><center><a href=" http://www. http://www.thecureforheartdisease.com/pauling/internetwks.com/pauling/index.html" target="_blank">MORE on Linus Pauling, Mathias Rath, Ascorbates and Cardiovascular Disease</a></center>
<br></font><center><font face="Verdana, Arial, Helvetica, sans-serif" size="2"><a href="http://www.thecureforheartdisease.com/pauling/lpatent.html" target="_blank"><font color="white">cure for heart disease</font></a></font></center></div><br><br>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-65362605330372404922012-05-17T08:50:00.000-07:002012-05-17T08:50:02.873-07:00BAKING SODA and CANCER CELLSThe cancer industry is closing in on baking soda and beginning to do research in earnest about sodium bicarbonate and how it is a primary tool in the treatment of fungus. Cancer is a fungus, can be caused by a fungus, or is accompanied by late-stage fungal infections, and now the Mayo Clinic confirms this. They are not the first to say so though. Many, even from the official world of orthodox oncology, recognize the similarities of cancer and fungal infections, the decay that ties these two together in a dance that all too often ends in miserable death.<br />
<br />
<br />
The Mayo Clinic is saying that a fungal infection of the gastrointestinal tract mimics cancer and inflammatory bowel disease. The invasive fungus, Basidiobolus ranarum, is typically found in the soil, decaying organic matter and the gastrointestinal tracts of fish, reptiles, amphibians, and bats.<br />
<br />
Patients with this fungal infection had non-specific symptoms such as abdominal pain or a mass that could be felt on examination. Before a conclusive diagnosis of the fungal infection was made, most patients were thought to have abdominal cancer, inflammatory bowel disease or diverticulitis. Surgical resection of the area of involvement and prolonged antifungal therapy successfully treated most patients.<br />
<br />
Interestingly, a few years ago researchers at Johns Hopkins were surprised that the drug itraconazole, commonly used to treat toenail fungus, can also block angiogenesis, the growth of new blood vessels commonly seen in cancers. Tumor angiogenesis is the proliferation of a network of blood vessels that penetrates into cancerous growths, supplying nutrients and oxygen and removing waste products. Cancer researchers studying the conditions necessary for cancer metastasis have discovered that angiogenesis is one of the critical events required for metasteses to occur. In mice induced to have excess blood vessel growth, treatment with itraconazole reduced blood vessel growth by 67% compared to placebo. "We were surprised, to say the least, that itraconazole popped up as a potential blocker of angiogenesis," says Dr. Jun O. Liu, professor of pharmacology. "We couldn't have predicted that an antifungal drug would have such a role." Itraconazole was found to reduce the numbers of circulating cancer cells, prevent the worsening of prostate cancers, and delay the need for chemotherapy. However, it has serious side effects when given in the necessary high dosages that include hypertension, low potassium levels and fluid retention. These side effects require treatment with other medications. Effects of high doses of itraconazole could lead to heart failure.<br />
<br />
For two decades John Hopkins has recognized the increasing frequency of severe fungal infections in patients with neoplastic diseases. Most fungal infections are caused by the commonly recognized opportunistic fungi Candida spp and Aspergillus spp, and the pathogenic fungi Cryptococcus neoformans, Histoplasma capsulatum, Coccidiodes immitis, and less often by Blastomyces dermatidis. However, recently newer pathogens such as Pheohyphomycetes, Hyalohyphomycetes, Zygomycetes and other fungi of emerging importance such as Torulopsis glabrata, Trichosporon beigelii, Malassezia spp, Saccharomyces spp, Hansenula spp, Rhodotorula spp, and Geotrichum candidum have appeared as significant causes of infection in this patient population.<br />
<br />
Dr. Tullio Simoncini does not say that cancer is caused by yeast; what he is telling the world is that the cancer is a yeast overgrowth. What causes the cancer (or a yeast-filled tumor) is another thing. Simoncini has always insisted that tumors are white because they are fungi. Some have made fun of him, but looking around at the extremely sparse information about the subject, I ran into one person saying:<br />
<br />
"If someone had asked me a year ago what color the inside of a tumor was, I would have guessed red and gray. When they did the biopsy, I asked to see the tissue specimens: five quarter-inch to half-inch strings of vermicelli (Italian for little worms) with little streakings of blood. They didn't look evil to me, just strings of fat. The entire mass was white inside as the pathology report stated.<br />
<br />
Specialists in throat and mouth cancer say that cancers can be red or white patches: any patch that appears randomly and is red or white in color could be a mouth cancer symptom. The white patches in the mouth are called leukoplakia and the red patches are called erythroplakia, which are pre-cancerous conditions. Though these red or white patches are not always cancerous, it could be the result of a fungal infection caused by Candida called thrush. Thrush will lead to a red patch that often bleeds after the white patch disappears. A small amount of this fungus lives in your mouth most of the time. It is usually kept in check by your immune system and other types of germs that also normally live in your mouth. However, when your immune system is weak, the fungus can grow.<br />
<br />
<strong>Fungal Mycotoxins</strong><br />
<br />
It just so happens that a toxin produced by mold on nuts and grains can cause liver cancer, according to University of California Irvine Researchers. And a French case-control study of 1,010 breast cancer cases and 1,950 controls with nonmalignant diseases found that breast cancer was associated with increased frequency of mold-fermented cheese consumption. Fungi produce mycotoxins, which can kill us or cause cancer.<br />
<br />
Dr. Wang and Groopman from the Environmental Health Sciences Department at Johns Hopkins published on the effects of mold toxins on DNA in Mutation Research, a leading cancer journal. They said mycotoxins with carcinogenic potency include aflatoxins, sterigmatocystin, ochratoxin, fumonisins, zearalenone, and some Penicillium toxins. Most of these carcinogenic mycotoxins are genotoxic agents. Aflatoxin is a potent genotoxic agent, is mutagenic in many model systems and produces chromosomal aberrations, micronuclei, sister chromatid exchange, unscheduled DNA synthesis, and chromosomal strand breaks. Most strikingly, the relationship between aflatoxin exposure and development of human hepatocellular carcinoma (liver cancer) is demonstrated by studies.<br />
<br />
Harrison et al. (1993) examined human breast cancer tissue for evidence of the presence of aflatoxin. The researchers examined human DNA from a variety of tissues and organs to identify and quantify aflatoxin DNA-adducts. Such adducts are considered to be proof of the mycotoxin's presence in a particular tissue. Aflatoxins may in fact be a risk factor for cancer induction in a variety of organs in man, in the same manner as that of cigarette smoking.<br />
<br />
DNA from normal and tumorous tissue obtained from patients with cancer of the breast was examined. Tumor tissues had higher aflatoxin-adduct levels than did normal tissue from the same individual. The result of this study verifies the presence of carcinogenic aflatoxin within the cancer tissue and thus implicates aflatoxin as a cause of breast cancer. That is the same as saying cancer is a fungus or is caused by a fungus and this is what Dr. Simoncini has been saying all along.<br />
<br />
Intensive Care Units are particularly on alert with immunocompromised and oncology patients for fungal infections. "Patients with brain tumors used to have a life expectancy of 3-12 months, but better treatment has allowed them to live a bit longer," said Brenda Shelton, clinical nurse specialist at the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore. "The last two brain tumor ICU patients we treated died of infection, not of their disease. One patient had a rare fungus, and the other had candidemia. Years ago, you would not see most of these fungal infections in patients with brain tumors because they would not live long enough."<br />
<br />
"The biggest misconception is the belief that fungal infections are rare," Shelton said. "Another misconception is fungal infections are like every other severe infection. They are harder to manage, harder to eradicate and more frequent than people realize." One of the most common complications involved in treating patients with hematologic cancer is fungal infections.<br />
<br />
Aspergillus niger fungal infection in human lungs produces large amounts of oxalic acid, which is extremely toxic to the blood vessels and which may cause fatal pulmonary hemorrhages. Consequently, oxalic acid (calcium oxalate crystals) in the sputum or lung specimens of patients is also an indication of an Aspergillus infection of the lung. These calcium oxalate crystals are the same as the calcium oxalate found in breast cancers. The presence of oxalates in the breast is indicative of the presence of fungi interwoven within the stages of breast cancer development. Since humans do not make oxalic acid themselves, this is an appropriate conclusion.<br />
<br />
Dr. Robert Young states, "Bacteria, yeast/fungi, and mold are not the cause of a cancerous condition but are the result and the evidence of cells and tissues biologically transforming from a healthy state and to an unhealthy state." Dr. Young astutely observed that, "over-acidification of the body leads to the development of chronic yeast and fungal infections and ultimately a cancerous condition of the cells and tissues."<br />
<br />
If one has cancer, chances are pretty good that one also has a fungal infection to one degree or another.<br />
<br />
According to The Home Medical Encyclopedia, in 1963 about one-half of all Americans suffered from an "unrecognized" systemic fungal condition. Far more Americans suffer from fungal infections today as antibiotics, hormone replacement therapies, and birth control pills continue to be consumed like candy. Thus more and more children are becoming infected with candidal meningitis or viral meningitis, which means their systems are suffering under the weight of fungi who put out an assortment of poisons - or mycotoxins.<br />
<br />
<strong>Sodium Bicarbonate is an Antifungal Agent</strong><br />
<br />
The current controversy over sodium bicarbonate and its use in oncology might be relatively new but baking soda has a long history of helping people get through the worst medical conditions. The Eloquent Peasant, an Egyptian literary work dated around 2000 B.C., refers to a peddler selling natron, a natural blend of sodium bicarbonate, chloride and sodium carbonate used in mummification, just one of hundreds of uses this compound has been put to. Baking soda's first widespread use was probably as a leavening agent for bread and other baked goods. It has been used commercially since 1775, although the now-famous Arm & Hammer brand wasn't introduced until 1867.<br />
<br />
Sodium bicarbonate (Na2HCO3) is recognized by most as ordinary baking soda, which is found in deposits around the globe. Its backbone characteristic is to maintain balance of carbon dioxide, bicarbonate and pH. Sodium bicarbonate is available and sold in every supermarket and pharmacy in the world and is widely used in emergency rooms and intensive care wards in injectable forms but is sold as a common household substance that is used for hundreds of different things.<br />
<br />
Read my book, Sodium Bicarbonate, and see that something as inexpensive as baking soda will outperform the most expensive pharmaceuticals. Across a wide range of disorders, including cancer and diabetes, we find conclusive evidence and plenty of theoretical backing to suggest that sodium bicarbonate is a frontline universal medicine that should be employed by all practitioners of the healing and medical arts for a broad range of disorders that are afflicting contemporary man.<br />
<br />
For all the references, sources and more articles, please visit Dr. Mark Sircus blog.<br />
<br />
About the author:<br />
<br />
Mark A. Sircus, Ac., OMD, is director of the International Medical Veritas Association (IMVA) <a href="http://www.imva.info/">http://www.imva.info/</a>.<br />
<br />
Dr. Sircus was trained in acupuncture and oriental medicine at the Institute of Traditional Medicine in Sante Fe, N.M., and at the School of Traditional Medicine of New England in Boston. He served at the Central Public Hospital of Pochutla in Mexico, and was awarded the title of doctor of oriental medicine for his work. He was one of the first nationally certified acupuncturists in the United States. Dr. Sircus's IMVA is dedicated to unifying the various disciplines in medicine with the goal of creating a new dawn in healthcare.<br />
<br />
He is particularly concerned about the effect vaccinations have on vulnerable infants and is identifying the common thread of many toxic agents that are dramatically threatening present and future generations of children. His book, The Terror of Pediatric Medicine, is a free e-book offered on his web site. Humane Pediatrics will be an e-book available early in 2011 and then quickly as possible put into print.<br />
<br />
Dr. Sircus is a most prolific and courageous writer and one can read through hundreds of pages on his various web sites.<br />
<br />
He has recently released a number of e-books including Winning the War Against Cancer, Survival Medicine for the 21st Century, Sodium Bicarbonate, Rich Man’s Poor Man’s Cancer Treatment, New Paradigms in Diabetic Care and Bringing Back the Universal Medicine: IODINE.<br />
<br />
Dr. Sircus is a pioneer in the area of natural detoxification and chelation of toxic chemicals and heavy metals. He is also a champion of the medicinal value of minerals and seawater.<br />
<br />
Transdermal Magnesium Therapy, his first published work, offers a stunning breakthrough in medicine, an entirely new way to supplement magnesium that naturally increases DHEA levels, brings cellular magnesium levels up quickly, relieves pain, brings down blood pressure and pushes cell physiology in a positive direction. Magnesium chloride delivered transdermally brings a quick release from a broad range of conditions. His second edition of Transdermal Magnesium Therapy will be out shortly. In addition he writes critically about the political and financial crises occurring around us.<br />
<br />
International Medical Veritas Association: <a href="http://www.imva.info/">http://www.imva.info/</a>/<br />
<br />
<a href="http://publications.imva.info/">http://publications.imva.info/</a><br />
<br />
Source: <a href="http://cancerstopped.blogspot.com/2012/05/baking-soda-and-cancer-cells.html">http://cancerstopped.blogspot.com/2012/05/baking-soda-and-cancer-cells.html</a><br />
<br />
<br />Unknownnoreply@blogger.com1tag:blogger.com,1999:blog-1517448691385361754.post-69233095880422656482012-05-15T10:21:00.000-07:002012-05-15T10:23:04.152-07:00FOR IMMEDIATE RELEASE<br />
<span style="font-size: x-small;">Orthomolecular Medicine News Service, May 14, 2012</span><br />
<br />
<div style="text-align: center;">
<strong>Fukushima Radiation Release is Worse than You Have Been Told</strong></div>
<br />
<div style="text-align: center;">
What You Can Do to Protect Yourself and those you care for.</div>
<div style="text-align: center;">
<br /></div>
<span style="font-size: x-small;">by Steve Hickey, PhD; Atsuo Yanagisawa, MD, PhD; Andrew W. Saul, PhD; Gert E. Schuitemaker, PhD; Damien Downing, MD</span><br />
<br />
(OMNS May 14, 2012) People have been misinformed about the tragedy at Fukushima and its consequences. There is a continuing cover up, the reactors have not been stabilized, and radiation continues to be released. The Japanese College of Intravenous Therapy (JCIT) has recently released a video for people wishing to learn more about how to protect themselves from contamination by taking large doses of vitamin C.<br />
<br />
Part 1 : <a href="http://www.youtube.com/watch?v=Rbm_MH3nSdM">http://www.youtube.com/watch?v=Rbm_MH3nSdM</a><br />
<br />
Part 2 : <a href="http://www.youtube.com/watch?v=j4cyzts3lMo">http://www.youtube.com/watch?v=j4cyzts3lMo</a><br />
<br />
Part 3 : <a href="http://www.youtube.com/watch?v=ZYiRo2Oucfo">http://www.youtube.com/watch?v=ZYiRo2Oucfo</a><br />
<br />
Part 4 : <a href="http://www.youtube.com/watch?v=51Ie8FuuYJw">http://www.youtube.com/watch?v=51Ie8FuuYJw</a><br />
<br />
All four parts of the video are also available here http://firstlaw.wordpress.com/. Readers may link to, embed in their webpages, and make copies of the video for free distribution.<br />
<br />
<div style="text-align: center;">
<strong>Japanese Government Minimizes Danger; Ignores Vitamin C</strong></div>
<br />
In the fall of 2011, JCIT presented a study that Fukushima workers had abnormality gene expression, which may be avoided using dietary antioxidants, especially vitamin C. The data was presented in Japan, Taiwan, and Korea. The JCIT sent letters to the government urging the government to tell the people how they may protect themselves from radiation. To date, the recommendation has been ignored by Japanese government and TEPCO (Tokyo Electric Power Company).<br />
<br />
Linus Pauling gained the Nobel Peace Prize in part based on his calculations of the number of deaths from nuclear weapons fallout.[1] He was supported by physicist and father of the Soviet bomb Andrei Sakharov, who also later received the Nobel Prize for peace.[2] These and other scientists estimated that there would be an extra 10,000 deaths worldwide for each megaton nuclear test in the atmosphere. A nuclear reactor can contain much more radioactive material than a nuclear weapon. Fukushima had six reactors, plus stored additional radioactive material and nuclear waste.<br />
<br />
<strong>How Radiation Damages Cells</strong><br />
<br />
Ionizing radiation acts to damage living tissue by forming free radicals. Essentially, electrons are ripped from molecules. Removing an electron from an atom or molecule turns it into an ion, hence the term ionizing radiation. X-rays, gamma rays, alpha- and beta-radiation are all ionizing.<br />
<br />
Most of the damage occurs from ionizing radiation generating free radicals in water, as water molecules are by far the most abundant in the body. While avoiding unnecessary exposure to ionizing radiation is clearly preferable, people affected by Fukushima do not have the luxury of avoiding contamination.<br />
<br />
<strong>Antioxidants: Free-Radical Scavengers</strong><br />
<br />
Free-radical scavengers, as the name suggests, mop up the damaging radicals produced by radiation. The more common term for free radical scavenger is antioxidant. Antioxidants replace the electrons stripped from molecules by ionizing radiation. Antioxidants have long been used in the treatment of radiation poisoning.[3-7] Most of the harm from ionizing radiation occurs from free radical damage which may be quenched by the free electrons antioxidants provide. Fortunately, safe antioxidants are widely available as nutritional supplements. Vitamin C is the prime example.<br />
<br />
<strong>Why Vitamin C?</strong><br />
<br />
Vitamin C is of particular importance and should be included at high intakes for anyone trying to minimize radiation poisoning. High dose vitamin C provides continual antioxidant flow through the body. It is absorbed from the gut and helps to replenish the other antioxidants. When it is used up, it is excreted in the urine. Importantly, it can chelate, or grab onto, radioactive heavy metal atoms and help eliminate them from the body. Large dynamic flow doses of vitamin C (about 3,000 mg, taken 4 times a day for a total of 12,000 mg) would exemplify antioxidant treatment. Higher doses have been used by Dr. Atsuo Yanagisawa and colleagues. [8,9]<br />
<br />
Shortly after the disaster, Dr. Damien Downing described how supplements can help protect against radioactive fallout.[10] OMNS issued an update on the response to Fukushima in Japan.[11] Recently, Dr. Gert Schuitemaker has provided a review of vitamin C as a radio-protectant for Fukushima contamination.[12]<br />
<br />
Persons living in the areas affected by radioactive contamination can take antioxidant supplements, especially high doses of vitamin C, to counteract the negative consequences of long-term low dose radiation exposure, as well as to protect the health of coming generations.[12,13] People who have a possible internal or external radiation exposure should take antioxidant supplements to maintain an optimal antioxidant reserve. Because of the enormous size and oceanic spread of Fukushima contamination, this literally applies to everyone.<br />
<br />
"The International Society for Orthomolecular Medicine is pleased to have participated in the making of this important DVD on the protective effects of intravenous vitamin C on radiation exposure from the Fukushima nuclear plant in March 2011. We are in full support of the valuable work of Dr. Yanagisawa and his colleagues, and we very much appreciate the commitment of Mr. Daisuke Shibata, who has made it possible for the free distribution of the video around the world. May this orthomolecular message raise awareness and foster improvement in the treatment of radiation exposure."<br />
<br />
Steven Carter<br />
<br />
Director, International Society for Orthomolecular Medicine<br />
<br />
<strong>References:</strong><br />
<br />
1. The Nobel Foundation (1962) The Nobel Peace Prize 1962, Linus Pauling Biography, <a href="http://www.nobelprize.org/nobel_prizes/peace/laureates/1962/pauling-bio.html">http://www.nobelprize.org/nobel_prizes/peace/laureates/1962/pauling-bio.html</a>.<br />
<br />
2. Sakharov A. (1975) The Nobel Peace Prize 1975, Andrei Sakharov, Autobiography, <a href="http://www.nobelprize.org/nobel_prizes/peace/laureates/1975/sakharov-autobio.html">http://www.nobelprize.org/nobel_prizes/peace/laureates/1975/sakharov-autobio.html</a>.<br />
<br />
3. Brown SL, Kolozsvary A, Liu J, et al: Antioxidant diet supplementation starting 24 hours after exposure reduces radiation lethality. Radiat Res, 2010; 173: 462-468.<br />
<br />
4. Zueva NA, Metelitsa LA, Kovalenko AN, et al: Immunomodulating effect of berlithione in clean-up workers of the Chernobyl nuclear plant accident [Article in Russian]. Lik Sprava, 2002; (1): 24-26.<br />
<br />
5. Yamamoto T, Kinoshita M et al. Pretreatment with ascorbic acid prevents lethal gastrointestinal syndrome in mice receiving a massive amount of radiation. J Radiat Res (Tokyo) 2010; 51(2):145-56<br />
<br />
6. Gaby A. Intravenous Nutrient Therapy: the "Myers' Cocktail". Alt Med Rev 2002; 7(5):389:403<br />
<br />
7. Narra VR, Howell RW, Sastry KS, Rao DV. Vitamin C as a radioprotector against iodine-131 in vivo. J Nucl Med 1993; 34(4):637-40<br />
<br />
8. Yanagisawa A. Orthomolecular approaches against radiation exposure. Presentation Orthomolecular Medicine Today Conference. Toronto 2011 <a href="http://www.doctoryourself.com/Radiation_VitC.pptx.pdf">http://www.doctoryourself.com/Radiation_VitC.pptx.pdf</a> )<br />
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9. Green MH, Lowe JE et al. Effect of diet and vitamin C on DNA strand breakage in freshly-isolated human white blood cells. Mutat Res 1994; 316(2):91-102<br />
<br />
10. Downing D. (2011) Radioactive Fallout: Can Nutritional Supplements Help?, A Personal Viewpoint, OMNS, May 10, <a href="http://www.orthomolecular.org/resources/omns/v07n04.shtml">http://www.orthomolecular.org/resources/omns/v07n04.shtml</a>.<br />
<br />
11. OMNS (2012) Vitamin C Prevents Radiation Damage, Nutritional Medicine in Japan, Orthomolecular Medicine News Service, February 1. <a href="http://orthomolecular.org/resources/omns/v08n06.shtml">http://orthomolecular.org/resources/omns/v08n06.shtml</a><br />
<br />
12. Schuitemaker GE. Vitamin C as protection against radiation exposure. J Orthomolecular Med 2011, 26: 3; 141-145. [Also in Dutch: Schuitemaker G.E. Radioactiviteit in Japan: Orthomoleculair antwoord. Ortho 2011:3, June. <a href="http://www.ortho.nl/">http://www.ortho.nl/</a> ]<br />
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13. Yanagisawa A, Uwabu M, Burkson BE, Weeks BS, Hunninghake R, Hickey S, Levy T, (2011) Environmental radioactivity and health. Official JCIT Statement, March 29. <a href="http://media.iv-therapy.jp/wp-content/uploads/2012/05/Statement.pdf">http://media.iv-therapy.jp/wp-content/uploads/2012/05/Statement.pdf</a><br />
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<div style="text-align: center;">
<strong>Nutritional Medicine is Orthomolecular Medicine</strong></div>
<div style="text-align: center;">
<br /></div>
Orthomolecular medicine uses safe, effective nutritional therapy to fight illness. For more information: <a href="http://www.orthomolecular.org/">http://www.orthomolecular.org/</a><br />
<br />
<strong>Find a Doctor</strong><br />
<br />
To locate an orthomolecular physician near you: <a href="http://orthomolecular.org/resources/omns/v06n09.shtml">http://orthomolecular.org/resources/omns/v06n09.shtml</a><br />
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The peer-reviewed Orthomolecular Medicine News Service is a non-profit and non-commercial informational resource.<br />
<br />
<strong>Editorial Review Board:</strong><br />
<br />
Ian Brighthope, M.D. (Australia)<br />
Ralph K. Campbell, M.D. (USA)<br />
Carolyn Dean, M.D., N.D. (USA)<br />
Damien Downing, M.D. (United Kingdom)<br />
Dean Elledge, D.D.S., M.S. (USA)<br />
Michael Ellis, M.D. (Australia)<br />
Martin P. Gallagher, M.D., D.C. (USA)<br />
Michael Gonzalez, D.Sc., Ph.D. (Puerto Rico)<br />
William B. Grant, Ph.D. (USA)<br />
Steve Hickey, Ph.D. (United Kingdom)<br />
James A. Jackson, Ph.D. (USA)<br />
Michael Janson, M.D. (USA)<br />
Robert E. Jenkins, D.C. (USA)<br />
Bo H. Jonsson, M.D., Ph.D. (Sweden)<br />
Thomas Levy, M.D., J.D. (USA)<br />
Stuart Lindsey, Pharm.D. (USA)<br />
Jorge R. Miranda-Massari, Pharm.D. (Puerto Rico)<br />
Karin Munsterhjelm-Ahumada, M.D. (Finland)<br />
Erik Paterson, M.D. (Canada)<br />
W. Todd Penberthy, Ph.D. (USA)<br />
Gert E. Schuitemaker, Ph.D. (Netherlands)<br />
Robert G. Smith, Ph.D. (USA)<br />
Jagan Nathan Vamanan, M.D. (India) <br />
<br />
Source: <a href="http://orthomolecular.org/resources/omns/v08n17.shtml">http://orthomolecular.org/resources/omns/v08n17.shtml</a><br />
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<br />Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-46543270391018337062012-05-15T10:10:00.000-07:002012-05-15T10:22:14.223-07:00RADIATION EXPOSURE & VITAMIN CObviously, it would be preferable to avoid unnecessary radioactive contamination, but that option is no longer available. It is particularly sad that the Japanese government has been inept, irrational, and dishonest in dealing with this tragedy. The rest of the world needs to know how to deal with this exposure.<br />
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There are options for radioactive-protection that have not been disclosed.When people cannot avoid radioactive contamination there are safe radioprotectants that can help prevent the damage. <br />
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Eating the right foods providing cellular nutrition, cesium carbonate prevents uptake of the radioactive form C137 and educating ourselves and others on the ways to remove the toxic waste from our cells with Vitamin C. (buffered mineral form is the best form of ascorbate)<br />
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Video Source: <a href="http://firstlaw.wordpress.com/">http://firstlaw.wordpress.com/</a>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-35224774887133685202012-03-28T18:07:00.000-07:002012-03-28T18:07:37.753-07:00Vitamin C: intravenous useVitamin C: intravenous use by complementary and alternative medicine practitioners and adverse effects.<br />
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Padayatty SJ, Sun AY, Chen Q, Espey MG, Drisko J, Levine M.<br />
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Source<br />
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Molecular and Clinical Nutrition Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.<br />
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Abstract<br />
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BACKGROUND:<br />
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Anecdotal information and case reports suggest that intravenously administered vitamin C is used by Complementary and Alternate Medicine (CAM) practitioners. The scale of such use in the U.S. and associated side effects are unknown.<br />
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METHODS AND FINDINGS:<br />
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We surveyed attendees at annual CAM Conferences in 2006 and 2008, and determined sales of intravenous vitamin C by major U.S. manufacturers/distributors. We also queried practitioners for side effects, compiled published cases, and analyzed FDA's Adverse Events Database. Of 199 survey respondents (out of 550), 172 practitioners administered IV vitamin C to 11,233 patients in 2006 and 8876 patients in 2008. Average dose was 28 grams every 4 days, with 22 total treatments per patient. Estimated yearly doses used (as 25 g/50 ml vials) were 318,539 in 2006 and 354,647 in 2008. Manufacturers' yearly sales were 750,000 and 855,000 vials, respectively. Common reasons for treatment included infection, cancer, and fatigue. Of 9,328 patients for whom data is available, 101 had side effects, mostly minor, including lethargy/fatigue in 59 patients, change in mental status in 21 patients and vein irritation/phlebitis in 6 patients. Publications documented serious adverse events, including 2 deaths in patients known to be at risk for IV vitamin C. Due to confounding causes, the FDA Adverse Events Database was uninformative. Total numbers of patients treated in the US with high dose vitamin C cannot be accurately estimated from this study.<br />
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CONCLUSIONS:<br />
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High dose IV vitamin C is in unexpectedly wide use by CAM practitioners. Other than the known complications of IV vitamin C in those with renal impairment or glucose 6 phosphate dehydrogenase deficiency, high dose intravenous vitamin C appears to be remarkably safe. Physicians should inquire about IV vitamin C use in patients with cancer, chronic, untreatable, or intractable conditions and be observant of unexpected harm, drug interactions, or benefit. <br />
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Source: <a href="http://www.ncbi.nlm.nih.gov/pubmed/20628650">http://www.ncbi.nlm.nih.gov/pubmed/20628650</a>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-45528093734252687132012-03-27T15:37:00.001-07:002012-03-27T15:40:45.723-07:00High Daily Intake of Ascorbic Acid<div style="text-align: center;"><strong><span style="font-size: large;">Significance of High Daily Intake of</span></strong></div><div style="text-align: center;"><strong><span style="font-size: large;"></span></strong></div><strong><div style="text-align: center;"><span style="font-size: large;"><br />
</span></div></strong><div style="text-align: center;"><strong><span style="font-size: large;">Ascorbic Acid in Preventive Medicine</span></strong></div><br />
<div style="text-align: center;"><strong>Frederick Robert Klenner, M.D., F.C.C.P., A.A.F.P.,</strong></div><div style="text-align: center;"><strong><br />
</strong></div><div style="text-align: center;"><strong>Private practice, Reidsville, N. C.</strong> </div><div style="text-align: center;"> </div>Frederick Robert Klenner, B.S., M.S., M.D., F.C.C.P., A.A.F.P., after graduating Duke University School of Medicine, March, 1936, took three years of hospital training and then entered the private practice of medicine at Reidsville, N.C. Although specializing in diseases of the chest, Dr. Klenner is engaged in a limited general practice which has enabled him to make observations on the use of massive doses of ascorbic acid in virus diseases as well as on other pathological syndromes. He has published 28 scientific papers on these observations and has given numerous lectures to civic and other groups. Dr. Klenner is a Fellow of the American Association for Advancement of Science; Fellow and Diplomate of The International College of Applied Nutrition; Fellow of The Royal Society of Health, London, England; Honorary Fellow of The International Academy of Preventive Medicine and a member and fellow of many other medical and scientific organizations.<br />
<br />
<b>Introduction</b>The American Medical Association in its introduction to Nostrums, Quackery and Pseudo-Medicine states: “In from 80 to 85 per cent of all cases of human ailment, it is probable that the individual will get well whether he does something for his indisposition or does nothing for it. The healing power of nature, fortunately for biologic perpetuity, works that way.” These percentages are relative. Increased population and greater concentration in terms of living patterns, as well as other types of insult to the body, will frequently change this index. As physicians we have a duty to get the patient well, irrespective of his chance for self-healing with diet or herbs. Hippocrates once declared, “Of several remedies physicians should choose the least sensational.” Vitamin C would seem to meet this requirement.<br />
<br />
<b>The Virus Story</b>The common cold has received renewed interest since publication of Pauling’s book. [1] Brody, [2] in 1953, after studying vitamin C and its effect on colds in college students, advised that ascorbic acid be given early and often and in sufficient amounts. This confirmed what we had been experiencing and reporting over a period of several years. The response that we observed with massive and frequent doses of ascorbic acid in treating the common cold alerted us to the real significance of this treatment in preventive medicine. <br />
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In February 1948, [3] I published my first paper on the use of massive doses of vitamin C in treating virus pathology. By February 1960, [4] some 25 scientific papers later, I realized that every head cold must be considered as a probable source of brain pathology. <br />
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Many have died, especially children, following the sudden development of cerebral manifestations secondary to even a slight head and/or chest cold. These insidious cerebral happenings are responsible for the so-called crib deaths attributed to suffocation. They die by suffocation, but by way of a syndrome similar to that found in cephalic tetanus toxemia culminating in diaphragmatic spasm, with dyspnea and finally asphyxia. These infants and children who have been put to bed apparently well, except for an insignificant nasal congestion, will demonstrate bilateral pneumonitis at autopsy. Adequate vitamin C, taken daily, will eliminate this syndrome. <br />
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A similar pathology, dubbed Crib Syndrome, is less acute but unless recognized and treated heroically, the infant will also die. This condition is probably due to severe brain trauma received at time of delivery. Laryngismus stridulous will be present in this condition and the child will sound as if it has a cold. Calcium gluconate and massive, frequent injections of vitamin C will also reverse this pathology. The recognized treatment is daily oral dihydrotachysterol. <br />
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Adequate ascorbic acid taken during the period of gestation will also prevent the occurrence of this syndrome. The information relative to crib syndrome is backed by case histories at Annie Penn Memorial Hospital, Reidsville, N. C. I have seen children dead in less than two hours after hospital admission, having received no treatment, simply because the attending physicians were not impressed with their illness. A few grams of ascorbic acid, given by needle, while they waited for laboratory procedures or examination to fit their schedule, could have saved their lives. I know this to be a fact because I have been in similar situations and by routinely employing ascorbic acid have seen death take a holiday. <br />
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In a paper titled “An Insidious Virus,” [5] I reasoned that it should be a maxim of medicine for large doses of vitamin C to be given in all pathological conditions while the physician ponders his diagnosis. The wisdom of this dictum is backed by many hundred cases under our supervision. I have seen critically ill chest patients well enough to go home after intravenous injection of 1 or 2 liters of 5% dextrose in water, each carrying 50 gm ascorbic acid. This procedure resulted in a dramatic transition from sickness to health.<br />
<br />
Virus encephalitis can also be associated with the common cold as a result of the presence of herpes simplex in cold sores. Lerner [6] and associates believe that thousands of cases exist yearly from this route. Of this number, they estimate that one third die; and of the survivors, eight out of nine have residual brain damage. Their work suggests that passive hemaggluting antibodies in the cerebrospinal fluid are a better indicator of the presence of infectious virus than are circulating antibody titers in the serum. <br />
<br />
The simple herpes virus from the insignificant fever blister, but possessing the capability of producing encephalitis, can remain hidden for years in the neuron according to Drs. Stephens and Cook. [7] This confirms the thinking of Goodpasture [ 8] given to us many years ago. Thus, a herpes simplex virus once present in a cold sore, although healed and leaving no evidence of lip pathology, could ignite later by simple exposure to ultraviolet light. How many mothers are endangering the lives of their children by sun-bathing, laboring under the belief that they are improving their health? Roizman [ 9] believes that all children are infected by age 5, but that only 1% experience true clinical illness. <br />
<br />
For many years investigators thought that each recurrence of fever blisters represented a new infection. Evidence is accumulating that shows the herpes simplex virus is harbored in dormant form until a physiologic or emotional event provokes the virus to produce the typical herpetic lesion. In one case with five repeats of herpes virus erupting at yearly intervals and at the same site, 7-10 gm ascorbic acid by mouth, daily, was found to eliminate this pathology.<br />
<br />
Effecting a cure when a virus is the offending agent, and many times bringing about this change in the short space of 24 hours, is a rewarding moment in medicine. Vitamin C treatment must be intensive to be successful. Use veins when practical, otherwise give vitamin C intramuscularly. Never give less than 350 mg/kg body weight. This must be repeated every hour for 6 to 12 times, depending upon clinical improvement, then every two to four hours until the patient has recovered. Ice cubes held to the gluteal muscle before and after injection will reduce or eliminate pain and induration. When treatment continues for several days, the child can be placed on an ice cap between injections. When employing vitamin C intravenously, it is best to use sodium ascorbate and the solution free of all additives except sodium bisulfite. The dose of vitamin C using a syringe should range between 350 mg and 400 mg/kg body weight. In older patients or when very high doses are required the vitamin can be added to 5% dextrose in water, in saline solution or in Ringer’s solution. The concentration should approximately be 1 gm to 18 cc fluid. Bottle injections will need 1 gm calcium gluconate one to two times each day to replace calcium ions removed by the high intravenous schedule. One quart of milk daily will suffice when using the vitamin intramuscularly. In place of milk one can substitute calcium gluconate tablets. Supplemental vitamin C is always given by mouth. As a guide in determining the amount and frequency of injections we recommend our Silver Nitrate-Urine test. [10] This is done by placing ten drops of 5% silver nitrate in a Wasserman tube and adding ten drops urine. A color pattern will develop showing white, beige, smoke gray or one that looks like fine grain charcoal. Charcoal is the color needed and the test is performed at least every four hours. The test itself is read in one minute.<br />
<br />
These large doses of ascorbic acid will also bring all body tissue back to saturation which means that the white blood cells will now be capable of destroying other pathogens that might be clouding the picture. Unless the white blood cells are saturated with ascorbic acid they are like soldiers without bullets. Research on this is now under way at the Bowman Gray School of Medicine by McCall and Cooper. [11] White cells ingest bacteria and in the process produce hydrogen peroxide. Hydrogen peroxide will combine with ascorbic acid to produce a substance which is lethal to bacteria. I have seen diphtheria, hemolytic streptococcus and staphylococcus infections clear within hours following injections of ascorbic acid in a dose range of from 500 mg to 700 mg/kg body weight given intravenously and run in through a 20G needle as fast as the patient’s cardiovascular system would allow.<br />
<br />
Part of the white cells are lymphocytes. They, too, play an important role in survival from infection. We found in several cases of trichinosis [12] that the behavior of the lymphocytes was the real story of the changing blood picture and actually determined the course of the disease. Wintrobe [ 13] observed that the function of the lymphocytes was stimulation of antibody formation and that the lymphocytic response runs parallel with the recovery of the patient. This build-up of antibodies appears directly proportional to the concentration of ascorbic acid in all body tissue, and yet we give vaccines but pay no attention to the degree of tissue saturation of ascorbic acid. Dr. Nossal [14] of the Institute of Medical Research, Melbourne, Australia, wonders about the mechanism by which lymphocytes, on meeting antigens, decide to be turned on or off. He asks what physiological mechanism underlies the discrimination between immunization and the induction of immunological tolerance and would suggest that it is controlled by vitamin C which in turn affects the negative charge which then influences the response of the lymphocyte. Ginter [15] of the Research Institute of Human Nutrition, Bratislava, offers some evidence to this effect in his statement: “that all reactions which are connected with vitamin C have oxidation-reduction features. It is therefore probable that the biological function of vitamin C can be located in the metabolic reactions which are connected with electron transfer.”<br />
<br />
The killing power of ascorbic acid is not limited to just herpes simplex and the adenovirus. When proper amounts are used it will destroy all virus organisms. <br />
<br />
We found measles to be a medical curiosity. Specifically we observe that vitamin C given prophylactically, by mouth, was not protective unless 1 gm was given every two hours around the clock. One gram every four hours would modify the attack. One gram given every four hours intramuscularly was also protective. With our own children we kept the measle syndrome going off and on for 30 days by giving 1 gm every two hours for two days, then off for two days. The disease was then stopped by continuing 1 gm every two hours, by mouth, for four days. By 1950 we learned that we could kill the measles virus in 24 hours by giving intramuscular injections in a dose range of 350 mg/kg body weight every 2 hours. We also found that we could dry up chicken pox in the same time, but more dramatic results were obtained by giving 400 mg/kg body weight intravenously. Two to three injections in 24 hours were all that was required. We published these results in 1951. [16] <br />
<br />
Recently, we cured a man weighing 85 kg in four days taking 30 gm each day by mouth. In conclusion, the killing power of ascorbic acid on virus bodies has been demonstrated by me in hundreds of cases, many of which were treated in our hospital with nothing but vitamin C. We have published some 28 papers on this matter.<br />
<br />
In certain individuals some virus conditions have a slower response. Herpes zoster and mumps belong to this group. We found that in these conditions equally rapid destruction of the virus could be effected through the use of adenosine-5-monophosphate. Adenosine was given according to age and weight, 25 mg in children and 50-100 mg intramuscularly in adults. This was given every 12 hours along with ascorbic acid. Adenosine will sometimes precipitate a mild reaction in that the patient will feel a fullness in his head with varying degrees of nausea. Inhalation of aromatic spirits of ammonia will quickly relieve and, if used before injection, will prevent this condition. Their response, when adenosine was administered, led us to theorize that when a cell has been invaded by a foreign substance, like virus nucleic acid, enzymic action fostered by ascorbic acid contributes to the breakdown of virus nucleic acid to adenosine deaminase which converts adenosine to inosine. <br />
<br />
Some individuals cannot manufacture sufficient adenosine to cope with this phase of purine metabolism under certain stress conditions associated with virus pathology. The net result from this chemical action is to catabolize purines rendering them unavailable for making additional virus nucleic acid. Ascorbic acid is further unique in that it possesses the capability of entering all cells. After entering a virus infected cell, ascorbic acid proceeds to take up the protein coats being manufactured by the virus nucleic acid, thus preventing the assembly of new virus units. These newly made macromolecules within the host cell soon create a situation where the tensile strength of the cell membrane is exceeded with resulting rupture and cell death. <br />
<br />
Ascorbic acid, when given in the massive amounts that accomplish full tissue saturation, will also enter those cells harboring the so-called dormant virus. Where the vitamin C removes the protective protein coat of the virus the micromolecule formed will act in the capacity of a repressor factor inhibiting further activity of the virus nucleic acid which is then destroyed by additional vitamin C. We offer as proof of this the instance of a patient having herpetic lesions for five years and being cured with continuous high daily intake of ascorbic acid. In acute virus infection, associated with a virusemia, ascorbic acid given intravenously will remove the protein protective coat from the virus body, leaving the denuded virus unit vulnerable to the leukocytes for destruction. Note that adrenal cortex extract and/or desoxycorticosterone acetate must also be considered for support of the adrenals in a debilitated patient.<br />
<br />
<strong>The Cholesterol Story</strong><br />
<br />
Next in importance to the virus is the story of cholesterol. One must understand, as noted by Ginter [17], that acute scurvy and chronic hypovitaminosis C are metabolically different conditions. On this point the Food and Life Yearbook, 1939, U. S. Department of Agriculture, had this to say: “Even when there is not a single outward symptom of trouble, a person may be in a state of vitamin C deficiency more dangerous than scurvy itself. When such a condition is not detected, and continues uncorrected, the teeth and bones will be damaged, and what may be even more serious, the blood stream is weakened to the point where it can no longer resist or fight infections not so easily cured as scurvy.”<br />
<br />
Working with guinea pigs many research groups have proved that acute avitaminosis C produces an increase m cholesterol concentration in the whole body. This increased concentration of whole body cholesterol in scorbutic guinea pigs can be caused either by increased biosynthesis or by slowed down cholesterol metabolism. The main pathway of cholesterol catabolism is in conversion to bile salts. <br />
<br />
The stimulating effect of ascorbic acid on the oxidation of polyunsaturated fatty acids and decreased oxidation of linolenic acid in the tissues of scorbutic guinea pigs has been well documented. Mjasnikova [ 18] found that intravenous injections of high doses of ascorbic acid to patients with high level blood cholesterol is followed by a distinct decrease of cholesterolemia. It must be remembered that the referred high doses of vitamin C employed by other scientists does not approach the dose schedule that we recommend. <br />
<br />
For example, Tjapina [19] reported on the effect of intravenous doses of 500 mg ascorbic acid on cholesterolemia in patients suffering from atherosclerosis. The hypocholesterolemic effect from vitamin C was apparent within one hour. With continued daily injections of 500 mg there was continued drop in blood cholesterol. Spittle [20] showed that blood cholesterol levels, in humans, vary with the amount of vitamin C employed. In our own experience we lowered the blood cholesterol in one patient 42 points in six weeks by increasing the vitamin C intake by mouth from 10 gm to 20 gm each day. Spittle advanced the theory that atherosclerosis is a long-term deficiency or negative balance of vitamin C, which permits cholesterol levels to build up in the arterial system and results in changes in other fractions of the fats. <br />
<br />
Ginter [21] also demonstrated that with a high cholesterol diet, guinea pigs used up all their dietary vitamin C while rats and rabbits who manufacture their own vitamin C showed a gain in ascorbic acid tissue levels. Ginter also showed that experimental animals given 50 mg vitamin C each day had cholesterol deposits 40% lower than animals fed the same diet but given only 5 mg of C daily. In a survey of 1000 school children Ginter et al showed that 97% suffered from vitamin C lack during winter months when C-rich fruits and vegetables were less abundant [22]. The children also showed corresponding rise in cholesterol. <br />
<br />
Czechoslovakian workers also reported that when guinea pigs are fed a diet deficient in vitamin C and rich in cholesterol, they frequently develop gallstones [23]. Small reported to the Society of University Surgeons in New Orleans in 1973 that when gallstones are removed from patients they are 60%-70% cholesterol [24]. This suggests a causative factor in human gallstone formation. Reviewing the literature and summarizing his own studies, Ginter concluded that there is no doubt that the daily intake of ascorbic acid in the control of cholesterol will have a more pronounced effect in those persons who are already saturated with vitamin C. Tjapina and many others have reported that when amounts of ascorbic acid as low as 500 mg each day, by needle, were continued for 60 days, the clinical picture in the majority of the patients was dramatic, especially concerning the manifestations of coronary artery disease. <br />
<br />
Willis [ 25] reported that in scorbutic guinea pigs, fatty deposits on the aorta were formed very quickly, even without adding cholesterol to their diet. In 1957, Willis [26] found that when ascorbic acid was given to these scorbutic guinea pigs, the atherosclerotic lesions were quickly absorbed. Ascorbic acid is directly associated with the mechanism involved in the pathogenesis of human atherosclerosis. Duguid [27] found alterations of ground substance observed in atherosclerosis that produced experimentally to be morphologically similar. Electrocardiographic tracings by Shafer [28] on scorbutic animals showed that with prolonged vitamin C therapy, abnormalities disappeared entirely. Stamler [ 29], following the mortality rate for middle aged persons, found a significant drop with improved nutrition with supplemental C.<br />
<br />
We must protect our heart from stress. Adequate vitamin C is one answer. Asahina and Asano [30] of the Toho University School of Medicine in Tokyo found that the larger the dose of ascorbic acid given to experimental rats, the longer they survived in decompression chambers in which the air was made to approximate that found at elevations of 33,000 feet. When ascorbic acid was given in amounts representing 14 gm in a human, only half their animals expired. In humans we have observed that 30 gm in 24 hours is critical in any acute situation. Had the Japanese doubled their vitamin C dose they probably would have had no deaths.<br />
<br />
<strong>The Heavy Metal Story</strong><br />
<br />
Heavy metal poisoning is another morbid chapter in medicine. Lead poisoning comes from many sources. Auto exhaust, smelter furnaces and storage battery factories lead the list. Mercury takes second place. It is estimated that at least I million children in the U. S. have some degree of lead poisoning. <br />
<br />
In 1964 Mokranjac and Petrovic [ 31] studied the effect of mercury chloride in guinea pigs when ascorbic acid was administered in different ways. They first gave each animal 200 mg of vitamin C a day for one week (this roughly would represent 14 gm in a human) and then administered a dose of mercury proved beforehand to be 100% fatal. They then continued to give 0.2 gm of vitamin C daily. After 20 days the animals were all alive proving that vitamin C had protected them from certain death. If they gave vitamin C before and none after poisoning, two died. If vitamin C was given daily after poisoning, nine of 25 died; and if a single massive shot was given after poisoning, eight of 25 died. This again confirms that high daily intake of vitamin C will protect one from many of the ills seen today. <br />
<br />
The same can be said for lead poisoning. One of the more common types of lead poisoning is seen in long-term workers in lead storage battery plants. All have subclinical scurvy. Adequate ascorbic acid intake would eliminate the monthly blood examination for red cell stippling. The report by Dannenberg [ 32] that high doses of ascorbic acid were without effect in treating lead intoxication in a child must be ignored, since his extremely high dose was 25 mg by mouth four times a day and one single daily injection of 250 mg of C. Had he administered 350 mg/kg body weight every two hours, he would have seen the other side of the coin.<br />
<br />
Monoxide poisoning is another killer or crippler. Persons living in most American cities are frequently exposed to 100 ppm (that is, 115 mg/cu mm) of carbon monoxide in the ambient air for varying periods of time and may attain carboxyhemoglobin blood levels up to 10% [33]. Carboxyhemoglobin blood levels up to 7% have been reported in cigarette smokers. These levels of carbon monoxide are quite capable of causing considerable interference with tissue oxygenation in man by displacing oxygen from the hemoglobin molecule and shifting the oxyhemoglobin dissociation curve to the left. Anderson [ 34] reports a definite link between carbon monoxide, both in the atmosphere and in cigarette smoke, with cardiac function. Normal coronary arteries can readily dilate and supply an increased demand; while diseased coronary arteries (e.g., angina pectoris) may not be able to meet this challenge. The hypoxic effect of carbon monoxide may act in a synergistic manner with other factors operative in ischemic heart disease, outstripping the limited coronary reserve and augmenting the production of stress-induced myocardial ischemia. <br />
<br />
Interesting is the report by Pelletier [ 35] who has shown experimentally that once you stop smoking, your ascorbic acid level approaches that of the nonsmoker. Victims of house fires, especially children, succumb more often to monoxide poisoning, which is overlooked in the course of treating the burn. Mayers [36] warns physicians that symptoms of smoke poisoning might be delayed from 3 to 48 hours. <br />
<br />
In cases of this nature ascorbic acid serves a dual purpose. A dose of 500 mg/kg body weight of vitamin C given intravenously will immediately neutralize the carbon monoxide or smoke poisoning while at the same time it will prevent blood sludging which is a major factor in the development of third degree burns.<br />
Other Applications<br />
<br />
Other therapeutic effects of vitamin C include the following. Vitamin C will also destroy pseudamonis, locally as a 3% spray and systemically with massive frequent injections. This has been demonstrated in case histories on burns treated at Annie Penn Memorial Hospital, Reidsville, N. C. It is a demonstrated principle that the production of histamine and other end products from deaminized cell proteins, released by injury to cells, is a cause of shock. <br />
<br />
The clinical value of ascorbic acid in combating shock is explained when we realize that the deaminizing enzymes from the damaged cells are inhibited by vitamin C. <br />
<br />
Chambers and Pollock [ 37] have reported that mechanical damage to a cell results in pH changes which reverse the cell enzymes from constructive to destructive activity. The destructive activity releases histamine, a major shock-producing substance. Ascorbic acid, when present in sufficient amounts, inhibits this enzyme transition.<br />
<br />
Ascorbic acid will reverse shock found in other areas of medicine. In one patient who had taken 2640 mg Lotusate (talbutal), the blood pressure was 60/0 when first seen in the emergency room. Twelve gm sodium ascorbate was administered with a 50 cc syringe. In ten minutes the blood pressure was recorded at 100/60. Over 100 additional grams were given intravenously over the following three hours, at which time the patient was awake. Shock from toxalbumin, neurotoxin, proteotoxin, muscarine and formic acid responds equally as well to high doses of vitamin C. Keeping the tissues saturated will prevent such experiences or make recovery by additional vitamin C a routine matter.<br />
<br />
Blumberg, writing in Medical World News, noted that the discovery of the Australian antigen raises hopes for an effective hepatitis vaccine. Many controversial studies have been reported in the use of this antigen. Another controversial substance, vitamin C, will cure viral hepatitis in two to four days and allow the patient to immediately resume his usual activities. It should be given in a dose range of 500 to 700 mg/kg body weight every 8 to 12 hours. Our latest case was given 5 gm sodium ascorbate, as crystals dissolved in 200 cc water or fruit juice, every 4 hours — i.e., 30 grams per 24-hour period. All symptoms and signs were removed in 96 hours. By contrast treating virus hepatitis with an immunizing agent would possibly require several vaccines in a single hepatic epidemic. If you want results, use adequate ascorbic acid.<br />
The Cancer Story<br />
<br />
The question of virus and cancer association is still academic. Herpes simplex causing cervical cancer appears to be positive. We have cured many fever blisters by applying a 3% ointment of vitamin C to the lip 10-15 times a day. This is put in a water soluble base. I think that it is time for those women with a family history of cervical cancer to douche with a 3% solution of ascorbic acid at the first report of cervical erosion. Tamponing with a 3% solution should also be done by the physician. Twenty grams of vitamin C daily by mouth along with local application of vitamin C could erase this form of malignancy. <br />
<br />
Virus and breast cancer, which in the mouse has been established, seems likely to be confirmed in women on the basis of a hereditary factor along with a virus role. Paul Broca (1866) pointed out that ten of 24 women among his immediate forebears had died of cancer of the breast. J. A. Murray (1911) demonstrated that mice with familial history of breast cancer developed breast cancer at an incidence three times that of mice with no familial history of tumor. Feller and associates found particles resembling type B and C viruses in eight of 16 human milk specimens from women with breast cancer but in only one of 43 apparently cancer-free women. These are stepping stones which serve to give warning that women from cancer-prone families should not breast feed their children. What will daily high intake of vitamin C do in altering the breast cancer picture? The answer is waiting for experimental work to be done with mice from knowledge gained from Bittner’s classic cross-suckling experiment.<br />
<br />
The role of ascorbic acid in treating virus cancer pathology can be seen with its action in mononucleosis. Large doses of vitamin C, given intravenously, will eliminate this virus in just a few days, the actual time being directly proportional to the amount of the vitamin employed in relation to the severity of the infection. A research team at Yale, after studying hundreds of college students, believe they have evidence that associates the Epstein-Barr virus with Burkett lymphoma [38, 39]. This has also been confirmed by researchers at Children’s Hospital, Philadelphia, Pa. Many investigators have been working with immunological procedures for the treatment of malignant disease. <br />
<br />
As we noted earlier, unless the patient’s tissues are saturated with vitamin C, the response in this area will be negated. Massive employment of vitamin C will make possible prolonged radiation therapy in late cases. It will also prevent radiation burns. Who can say what 100 gm or 300 gm given intravenously, daily, for several months might accomplish in cancer. The potential is so great and the employment so elementary that only the illiterate will continue to deny its use. Schlegel [ 40] has demonstrated that the use of ascorbic acid as low as 1.5 gm each day will prevent recurrence of bladder cancer. This is the so-called wasted vitamin C.<br />
Other Applications<br />
<br />
Rous [41] has found that just 3 gm daily, by mouth, for four days will completely relieve all symptoms of urethritis. He believes that the urethral irritation is caused by phosphatic crystals formed in the urine because of insufficient acidity. Ascorbic acid, in this case, acidified the urine enough to force the crystals back into solution. The neglected chronic cystitis which is the rule with ammonical decomposition in the bladder, most always associated with marked alkalinity of the freshly voided urine, will cease to be a clinical entity once people take at least 10 gm vitamin C every day. This will also eliminate the backwash type pyelitis so debilitating, especially in women of childbearing age.<br />
<br />
In over 300 consecutive obstetrical cases, we found that the simple stress of pregnancy increased the ascorbic acid demand up to 15 gm daily. This simple stress of pregnancy becomes meaningful when we review the work of Conney [42] on mammalian synthesis of vitamin C in the rat. Compared to a 70 kg individual the rat would make, under stress, 15.2 gm of C each day. Compare this to the 100 mg now recommended in pregnancy by the National Academy of Science and National Research Council and the disparity is shocking. Fred Stare’s 40 mg/day is catastrophic. <br />
<br />
This must be changed. There are at least 16 categories [42], not including scurvy, that cry out against minimal daily requirements for vitamin C. There can never exist a situation where a set numerical unit of vitamin C will meet the needs of all men. This is true because people are different and these same people experience different situations at various times. Roger Williams, speaking before the National Academy of Science in 1967, reported that among guinea pigs living in his laboratory, some needed 20 times more vitamin C than others to maintain health. <br />
<br />
We must accept Ginter’s conclusion that acute scurvy and chronic hypovitaminosis C are metabolically different conditions. Antonowicz and Kodicek (1969), working with guinea pigs, discovered an extremely complex chemical process existing in animals receiving ascorbic acid which did not occur in the animals with scurvy. They found that glucosamine synthesis with the formation of galactosamine was normal in those animals receiving vitamin C but did not take place in those with scurvy.<br />
<br />
Under a grant from the National Institute of Mental Health, Hepler and associates, according to Medical Tribune, reported that marijuana smoking caused a significant decrease in intraocular pressure. This decrease was found 30 minutes after smoking. In fine print they conceded that the drop was not significant after three hours. Thus, one would need be a chain-link smoker to maintain worthwhile levels [ 43, 44]. No mention was made of the many deleterious effects smoking marijuana has on the human body. Virno and associates [45], working in G. B. Bietti’s eye clinic observed a pronounced reduction in intraocular pressure in the glaucomatous eyes by giving high daily doses of vitamin C. <br />
<br />
Bietti states that these high doses of vitamin C are a very effective hypotonic agent for intraocular pressure and when an intravenous dose calculated at 1 gm/kg body weight is administered, the action is predominantly by osmotic dehydration of the eyeball. Virno employed 35 gm by mouth in divided doses each day. This gave marked reduction of pressure within four hours and this was maintained even in patients where Diamox and Philocarpone had failed. Linner in several symposiums using 0.5 gm twice daily reported no significant changes in eye pressure. Linner used 1 gm and Virno 35 gm each day — thus the difference in results. In the 1940s patients died receiving 5,000-10,000 units penicillin every four to six hours. The same type pathology is cured today in 24 to 48 hours using 1-3 million units. The size of the dose does make a difference — a real difference.<br />
<br />
Dr. Linus Pauling has written that “Biochemical and genetic arguments support the idea that orthomolecular therapy may be the preferred treatment for many ill patients.” It is difficult to understand why megavitamin therapy remains so controversial when massive doses of vitamin B12 are universally used in pernicious anemia and niacinamide to correct the pathology of pellagra. I have used 150,000-200,000 units of vitamin A in a case of ichthyosis. The patient has been taking this dose for ten years. His skin is clear with no signs or symptoms of vitamin A toxicity. During the same time he has taken 10 gm of vitamin C each day. Is vitamin C the answer?<br />
<br />
Hoffer [46] and Osmond were probably the first to realize the value of ascorbic acid as an adjuvant with niacin in treating schizophrenics. They employed from 6 to 8 gm daily. One acute case was given 1 gm every hour for 48 hours at which time the patient was completely recovered and remained so for six months without further treatment. <br />
<br />
Hawkins [47] found that by adding megavitamin treatment he doubled the recovery rate, half the rehospitalization rate and virtually eliminated self-destruction in dealing with schizophrenics who have a suicide rate 22 times that of the general population. Dr. Pauling enabled his clinic to treat seriously ill schizophrenics for $200 per patient per year and to reduce the number of patient visits from 150 per year to 15. Hawkins’ method gives schizophrenic patients four gm ascorbic acid and four gm niacin or the equivalent in niacinamide, in divided doses, each day. <br />
<br />
Vanderkamp (1966) demonstrated that schizophrenics burn up ascorbic acid ten times faster than normal people. On an intake of four gm vitamin C each day, almost 100% of normal people will spill some degree of ascorbic acid into the urine. In schizophrenics one can often go as high as 40 grams/day before spilling occurs. I have observed this same picture in severe virus infections where the patient did not spill over the urine until the second or third day, when a clinical response was evident. Milmer in Great Britain and Lucksch in Germany have reported significant improvement in schizophrenics given vitamin C alone. Both investigators used the double blind approach.<br />
<br />
Ascorbic acid has value as an adjuvant in other medical syndromes. With para-aminobenzoic acid (PABA), which is a fraction of the B vitamins, it will cure trichinosis in nine days [48]. Used with intravenous mephenesin or methocarbamol, it will cure tetanus in 96 hours.<br />
<br />
Arthritis is not only a crippler but also a nagger. Aspirin is the favorite medication of many physicians because it will ease the arthritic pain. This makes aspirin a good guy and a bad guy. The bad side is that those who take high aspirin therapy will also have low platelet and plasma levels for vitamin C. With low plasma levels there will also be depletion in the white blood cells. We know what this will do. As to platelets, their main business is to keep people from bleeding to death. <br />
<br />
When a blood vessel ruptures, collagen tissue, which makes up the basement membrane of blood vessels, is exposed. The collagen affects the platelets so that they release a mineral substance called adenosine diphosphate. This substance makes the platelets very sticky so that they cling together. Aspirin can destroy this substance, but adequate vitamin C will prevent this action. As the platelets act to seal off the wound, a second mechanism for clot formation comes into play. This is a liquid protein called fibrinogen. In a recent case in which the platelet count was abnormally low and bleeding was a serious problem, 25 gm of ascorbic acid daily by mouth raised the platelet count back to normal with cessation of bleeding. Vitamin C is also the number one agent in collagen formation. <br />
<br />
A person who will take 10-20 gm of ascorbic acid a day along with other nutrients might very well never develop arthritis. Abrams and Sandson [49] have pointed out that synovial fluid becomes thinner, thus allowing easier movement, when serum levels of ascorbic acid are high. Drugs such as ACTH and cortisone are noted for their ability to drain ascorbic acid in prolonged usage. In our experience we found that the patient who took vitamin C to tolerance made more rapid progress in reversing arthritic joints.<br />
<br />
The importance of daily high intake of ascorbic acid in preventive medicine has no limits. Crest and Colgate might limit tooth decay to one cavity every checkup, a relatively high index. Ten or more gm of ascorbic acid from age 10 up and at least 1 gm for each year of life, each day, through age 9 will record no cavities. Our son who is 20 has never had a tooth cavity. The same schedule could eliminate disc pathology. McCormick believes the problem is avitaminosis C [ 50]. <br />
<br />
Greenwood [ 51] believes that adequate amounts of ascorbic acid seem necessary to disc metabolism and maintenance. In surgery we found that plasma determinations taken before starting anesthesia, at the conclusion of surgery, and six hours later, were constant. At 12 hours postoperative, there was a significant drop in vitamin C levels and at 24 hours there was a dramatic loss of the vitamin. We have always required the surgeon to give 10 gm before surgery, 10 gm in each postoperative bottle of fluids and 10 gm by mouth after discontinuing fluids. Crandon et al state that postoperative disruption of abdominal wounds occurs eight times more often in patients with vitamin C deficiency. Not only surgery but any type of wound or fracture will heal slowly or not heal at all without the benefits of adequate vitamin C. <br />
<br />
Powdered vitamin C mixed with water to form a paste and applied to poison ivy or oak will usually effect a cure in 24 hours when adequate vitamin C is also taken by mouth. Ascorbic acid does have a definite influence on the rheumatic heart, especially in the acute stage [52]. I have seen children with the heart impulse so great that it raised the bed covers with each contraction recover so completely that later in life they were inducted into the armed services. <br />
<br />
Massive daily doses will also cure tuberculosis by removal of the organisms’ polysaccharide coat. It does the same with pneumococci. I am convinced that ten or more grams a day will prevent cancer of the lung in tobacco smokers. <br />
<br />
It will relieve prickly heat and prevent heat stroke. Vitamin C will immediately reverse heat collapse, cramps or exhaustion if 12 to 40 gm are given intravenously. It will bring recovery to electric shock victims if sufficient amounts are administered soon after the accident. Lightning victims can also be saved. I have done it. Chronic myelocytic leukemia responds dramatically to 30 or more grams daily by mouth. <br />
<br />
Pancreatitis can be cured in less than three hours with 50 gm intravenously, and ten gm daily by mouth is positive insurance that it will never return. Virus pancarditis as a sequela of an adenovirus infection can be relieved in 36 hours giving 400 mg/kg body weight, intravenously, every four to six hours. I have never seen a patient that vitamin C would not benefit. And, too, never send a boy to do a man’s job; meaning the dose level is very important.<br />
<br />
In closing, I would like to quote Herbert Spencer, who summed up rather well a caution I would like all of us to take to heart: “There is a principle which is a bar against all information, which is proof against all argument, and which cannot fail to keep a man in everlasting ignorance. That principle is condemnation without investigation.”<br />
<br />
<strong>Summary</strong><br />
<br />
The drug evaluation book of the American Medical Association (1971) gives information on the value of ascorbic acid which is at least 30 years behind present day knowledge. The 200-500 mg of ascorbic acid which is recommended as the 24-hour dose in burn cases is a typical example. From clinical experience we know that ascorbic acid must be given to burn victims in massive, frequent intravenous injections. Thirty to one hundred grams daily is the proper amount to employ and this is given until healing takes place — 7-30 days depending upon the degree of burn. <br />
<br />
We have found and reported that this massive vitamin C therapy will eliminate skin grafting by keeping the tissues oxygenated. Ample supply of oxygen to the tissues will prevent blood sludging and in place of the third degree burns that develop on the fourth or fifth day, the eschars will drop off leaving normal tissue. <br />
<br />
These high doses of ascorbic acid will also remove the smoke poisoning found in many fire victims and save many lives, especially children who expire from the effects of monoxide gas. The statement found in the A.M.A. book mentioned above — that controlled studies have shown no benefit from large doses of ascorbic acid in human subjects — must be ignored. The large doses referred to never exceeded 5 gm and in most cases not more than that found in a quart of orange juice, for a 24-hour period. It is unfortunate that the editorial staff of the AMA failed to check out the world literature. An example of their high doses was an article by Dannenberg [ 32] which was published in the JAMA in which the author found no value in lead poisoning by giving extremely high doses of ascorbic acid to a child. Dannenberg’s extremely high dose was 25 mg four times a day, by mouth, and one single intramuscular injection of 250 mg. Had Dannenberg employed 350 mg/kg body weight and given it, intramuscularly, every two to four hours he would have had a recovered patient in less than 72 hours. <br />
<br />
The amount of ascorbic acid employed in any given case is the all important factor. In 28 years of research we have observed that 30 gm each day is critical in terms of response. This seems to be true regardless of age and weight. In certain pathological conditions like barbiturate intoxication, snake bite or virus encephalitis, higher doses are required in some individuals. We have observed from experience and from review of the literature that 15%-20% of humans require much more ascorbic acid than do others. <br />
<br />
Approximately 15% is in evidence when giving vaccines, since they make no antibodies. Roughly 15% of pregnant humans were scheduled, in the past, to become paralyzed if hit with the polio virus. Fifteen percent of over 3000 cases in our files required more ascorbic acid to prevent colds or to relieve the cold once infected. This percentage difference is the reason why one patient would die with pneumonia while another lived, when all other factors were apparently equal. This dosage factor alone has misled many scientists to disregard the value of ascorbic acid in virus pathology because they would see dogs die with distemper when they knew that the dog could make his own vitamin C. What they did not appreciate was that even the animal could not make enough vitamin C under certain situations. I have cured many dogs suffering with distemper by giving several grams ascorbic acid, by needle, every two hours. <br />
<br />
We also found in over 300 obstetrical cases that roughly 15% require as much as 15 gm supplemental vitamin C each day just to remain within normal limits. Ten grams each day was the highest requirement of the other 85%.<br />
<br />
Herpes simplex virus and the adenovirus can be destroyed with high doses of ascorbic acid. Many infections can be prevented by taking adequate vitamin C, daily, by mouth — 1 gm for each year of life up to age 10 and after 10 years of age at least 10 gm vitamin C daily. With these amounts the patient will spill varying amounts into the urine. The kidneys have a threshold for vitamin C much like the spillway of a dam. Spilling is necessary to assure adequate amounts for various body tissues. <br />
<br />
For example, white blood cells are useless unless they are full of ascorbic acid, since it is the ascorbic acid which makes their phagocytosis and/or destruction of pathogens possible. Although herpes simplex usually shows itself as a small lip sore and the adenoviruses as a mild but lingering cold, both can become killers through passage of the virus to the brain. Either one can cause crib deaths, which is truly the real cause. <br />
<br />
Again, we point out that high daily intake of vitamin C can prevent this tragic incident. For this reason, if for no other, the National Research Council and the National Academy of Science must remove the so-called minimal daily requirement for this substance. Williams has shown and reported to the National Academy that even guinea pigs living in his laboratory differ in their requirements for vitamin C and that they differ each day, sometimes 20 times a given unit. Guinea pigs, like man, cannot manufacture ascorbic acid due to genetic fault. Scurvy which accounts for the thinking on the amount of vitamin C needed is actually of no consequence m terms of avitaminosis C, which can determine one’s future existence. <br />
<br />
Ginter, after ten years of research with vitamin C, concluded that acute scurvy and chronic hypovitaminosis C are metabolically different conditions. Antonowicz and Kodick confirmed this by finding that glucosamine synthesis in the guinea pig with the formation of galactosamine was normal in those animals receiving vitamin C but did not take place in the presence of acute scurvy.<br />
<br />
Ascorbic acid when taken in sufficient quantities will relieve the intraocular pressure in the glaucomatous eyes, will relieve such things as prickly heat, and is a positive reversal for pemphigus. <br />
<br />
Vitamin C when given by needle will destroy all viruses and many can be destroyed by taking 25-30 gm each day by mouth. Lesser amounts will protect against these pathogens. <br />
<br />
I have cured diphtheria, hemolytic streptococcus and staphylococcus infections by employing vitamin C intravenously in a dose range of 500 to 700 mg/kg body weight. Doses under 400 mg/kg body weight can be given with a syringe using the sodium salt. This will always produce thirst. Fluids taken just before or immediately after will eliminate this annoyance. Doses above 400 mg/kg body weight must be diluted to at least 1 gm to 18 cc solution, using 5% dextrose in water, saline in water or Ringer’s solution. One gram calcium gluconate must be added to these bottle injections to replace Ca ions pulled from the calcium-prothrombin complex. There is no limit to the amount that can be administered by vein when honoring these two precautions. <br />
<br />
The use of vitamin C in cancer will prove to be a very beneficial agent. <br />
<br />
We recommend bottle doses containing 60 gm vitamin C and such fractions of the B complex as 500 mg thiamin HCl, pyridoxine 300 mg, calcium pantothenate 400 mg, riboflavin 100 mg and niacinamide 300 mg. This is to be given daily or even twice daily. Vitamin C is a positive neutralizing agent in snake bite [53], spider bite [54] and insect stings. <br />
<br />
Our use of ascorbic acid in snake bite has been limited to the Highland moccasin, a member of the copperhead family. Other poisonous snakes are more deadly but we can easily calculate from our experience what dose to employ. In a 4-year-old receiving a full strike from a mature Highland moccasin, 12 gm was required. Unlike a virus that will continue production until completely destroyed, the venom of the snake is constant in that there will exist no later increase in amount. I would suggest 40-60 gin, as a starter, in a large diamondback or cottonmouth. Additional vitamin C can be given if needed since the patient will be well on the road to recovery with the first injection.<br />
<br />
Adenosine monophosphate given with ascorbic acid will increase the potential of the vitamin. This can be given in doses from 25 mg in children to as much as 200 mg in adults. Our use of this agent has been limited to mumps and herpes zoster but we are now of sufficient knowledge to believe that its use should be routine. The aqueous solution is more efficacious than the gel. Some patients experience a fullness in the head, a sickish feeling in the chest and a slowed pulse rate. Aromatic spirits of ammonia as a smelling agent relieves or prevents this syndrome. At present we are using 50 mg doses more frequently, until we can establish a reason for this type response.<br />
<br />
Ascorbic acid can be lifesaving in shock. Twelve grams of the sodium salt given with a 50 cc syringe will reverse shock in minutes. In barbiturate poisoning and monoxide poisoning the results are so dramatic that it borders on malpractice to deny this therapy. <br />
<br />
Surgeons must learn to employ ascorbic acid more liberally. Ten to twenty grams in the preoperative solutions and 10 gm in each postoperative bottle will all but eliminate surgical deaths and will reduce hospital stay by 50%. The same can be said for obstetrical cases. We found that obstetrical cases needed 4 gm each day the first trimester, 6 gm the second trimester and 8-10 gm the third trimester. Fifteen percent of the patients required 15 gm each day just to stay within normal limits.<br />
<br />
Ascorbic acid is the safest and the most valuable substance available to the physician. Many headaches and many heartaches will be avoided with its proper use.<br />
References<br />
<br />
Pauling, L.: Vitamin C and the Common Cold San Francisco: W. F. Freeman & Co., 1970.<br />
Brody, H. D.: J. Amer. Diet. Ass., 29:588, 1953.<br />
Klenner, F. R.: Virus pneumoniaand its treatment with vitamin C Southern Med. Surg., Feb. 1948.<br />
Klenner, F. R.: Encephalitis as a sequelae of the pneumonias. Tri-State Med. J., Feb. 1960.<br />
Klenner, F. R.: An insidious virus. Tri-State Med. J., June 1957.<br />
Lerner, M. et al: Detecting herpes encephalitis earlier. Med. World News, May 26, 1972.<br />
Stephens, J. C. and Cook, M. Cases of the hidden herpes virus. Med. World News, Feb. 25, 1972.<br />
Goodpasture, E. W.: Case of the hidden herpes virus. Med. World News, Feb. 25, 1972.<br />
Roizman, B. et al: Tracing herpes viruses. Med. World News, Oct. 1, 1971.<br />
Klenner, F. R.: A new office procedure for the determination of plasma levels for ascorbic acid. Tri-State Med. J., 5, 1956.<br />
McCall, C. E. and Copper, R.: Vitamin C shows promise as a bactericidal agent. Bowman Gray School Med. Med. Alumni News, 14:1, Feb., 1972.<br />
Klenner, F. R.: The treatment of trichinosis with massive doses of vitamin C and para-aminobenzoic acid. Tri-State Med. J., 1952.<br />
Wintrobe, M. M.: Clinical Hematology. Text Book. Lea and Febiger, 3rd Edition, 1952.<br />
Nossal, G.: Most killed vaccines in use termed not fit for a mouse. Medical Tribune, April 5, 1972.<br />
Ginter, E.: The Role of Ascorbic Acid In Cholesterol Metabolism. Research Institute of Human Nutrition, Bratislava, 1970.<br />
Klenner, F. R.: Massive doses of vitamin C and the virus diseases. Southern Med. Surg., 1951.<br />
Ginter, E.: Cholesterol and vitamin C. Amer. J. Clin. Nutr., 24:1238-1245, 1971.<br />
Mjasnikova, I. A.: O vlijaniji vodorastvorimych vitaminov na nekororyje storony obmena vescesty. Tr. Vojennomorskof medicinsk. akademiji Leningr., 8:140-148, 1947.<br />
Tjapina, L. A.: Vlijanie askorbovoj kisloty na cholesterinemiju pri giper toniceskoj bolezm i ateroskleroze. Gipertoniceskaja bolezn. Tr. AMN SSSR, 2:108-113, 1952.<br />
Spittle, C.: Atherosclerosis and vitamin C. Lancet, 11:1280-1281, 1971.<br />
Ginter, E.: Effects of dietary cholesterol on vitamin C metabolism in laboratory animals. Acta med. Acad. Sci Hung., 27:23-29, 1970.<br />
Ginter, E., Kajabal, I. and Nizner, O.: The effects of ascorbic acid on cholesterolemia in healthy subjects with seasonal deficit of vitamin C. Nutr. MetaboL, 12:76-86, 1970.<br />
Ginter, E., Bilisics, I. and Cerven, J.: Cholesterol metabolism under conditions of acute and chronic vitamin C deficiency in guinea pigs. PhysioL Bohemoslov., 14:466-471, 1965.<br />
Small, D.: Med. World News, March 30, 1971.<br />
Willis, G. C.: An experimental study of the intimal ground substance in atherosclerosis. Canad. Med. Ass. J., 69:17-22, 1953.<br />
Willis, G. C.: The Reversibility of Atherosclerosis. Canad. Med. Ass. J., 77:106-109, 1957.<br />
Duguid, J. B.: Pathogenesis of atherosclerosis. Lancet, 2:925, 1957.<br />
Shafer, C. F.: Ascorbic acid and atherosclerosis. Amer. J. Clin. Nutr., 23:27, 1970.<br />
Stamler, J.: Comprehensive Treatment of Essential Hypertensive Diseases. Monograph on Hypertension. Merck, Sharp and Dohme.<br />
Asahina and Asano: Prevention, July 1972. pp. 8 1-82.<br />
Mokranjac, M., Petrovic, C.: Report on mercury studies in guinea pigs in relation to amounts of vitamin C administered. C. R. Acad. Sci., Paris.<br />
Dannenberg, A. M. et al: Ascorbic acid in the treatment of chronic lead poisoning. JAMA, 114:1439-1440, 1940.<br />
Klenner, F. R.: The role of ascorbic acid in therapeutics. Tri-State Med. J., Nov. 1955.<br />
Anderson, E: W. et al: Carbon monoxide linked to heart disease. JAMA,22:5, July 1972.<br />
Pelletier, O.: Experiments with smokers and non-smokers. JAMA, April 1969.<br />
Mayers, B. W.: Where there’s smoke there may be carbon monoxide. Med. World News, Jan. 21, 1972.<br />
Chambers, R. and Pollock, H.: J. Gen. Physiol., 10:739, 1927.<br />
Hellne, G. and Helene, W.: EB virus in the etiology of infectious mononucleosis. Hosp. Practice, July 1970.<br />
Niderman, J. C.: College findings tie mono to EB virus. Med. World News, Dec. 1968.<br />
Schlegel, G. E. et al: The role of ascorbic acid in the prevention of bladder tumor formation. Trans. Amer. Ass. Genitourin. Surg., 61, 1969.<br />
Rous, S.: Urethritis in men. N. Y. Soc. Med., Dec. 15, 1971.<br />
Klenner, F. R.: Observations on the dose and administration of ascorbic acid when employed beyond the range of a vitamin in human pathology. J. Appl. Nutr., 23:3-4, 1971.<br />
Leuchtenberger, C. and Leuchtenberger, R.: New dangers seen in marijuana. Nature, Nov. 1971.<br />
Campbell, A. M. G. et al: Significant brain damage caused by smoking marijuana. Lancet, Dec. 1971.<br />
Virno, M. et al: Eye, Ear, Nose, Throat Monthly, 64, Dec. 1967.<br />
Hoffer, A.: Use of ascorbic acid with niacin in schizophrenia. Canad. Med. J., Nov. 6, 1971.<br />
Hawkins, D.: Back to reality the megavitamin way. Med. World News, September 24, 1971.<br />
Klenner, F. R.: Recent discoveries in the treatment of lockjaw with vitamin C and Tolserol. Tri-State Med. J., July 1954.<br />
Abrams, E. and Sandson, J.: Ann. Rheum. Dis., 27, 1964.<br />
McCormick, W. J.: Intervertable Disc Pathology: A new etiologic concept. Arch. Pre., 71:29, 1954.<br />
Greenwood, J.: Optimum vitamin C intake as a factor in the preservation of disc integrity. Med. Ann. D. C., 33:6, June 1964.<br />
Massell, B. F., Warren, J. E., Patterson, P. R. et al: Antirheumatic activity of ascorbic acid in large doses. New Eng. J. Med., 1950.<br />
Klenner, F. R.: Case history: Cure of a 4 year old child bitten by a mature Hiland moccasin with vitamin C. Tri-State Med. J., July, 1954.<br />
Klenner, F. R.: Case history: The black widow spider. Tri-State Med. J., Dec. 1957.<br />
<br />
From Journal of the International Academy of Preventive Medicine, Spring 1974, Volume 1, Number 1, pp. 45-69<br />
<br />
HTML Revised 23 March, 2003.<br />
Corrections and formatting © 1999-2003 AscorbateWeb<br />
<br />
SOURCE: <a href="http://theashbulletin.blogspot.com/">http://theashbulletin.blogspot.com/</a>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-12879962817434769222012-03-25T14:58:00.000-07:002012-03-25T14:58:05.309-07:00Intravenous Vitamin C and Cancer"...it takes much more than logic and clear-cut demonstrations to overcome the inertia and dogma of established thought." — Irving Stone <br />
<br />
Irving Stone was an early thinker and writer about vitamin C (its scientific name is ascorbic acid). He knew it would be an uphill battle to change the way the medical profession viewed vitamin C. While most doctors accept that scurvy is a vitamin C deficiency illness, few have made the rather humongous jump to seeing high dose intravenous vitamin C as a major player in the management of cancer. <br />
<br />
There is actually a wide spectrum of medical uses for vitamin C. Evidence exists documenting it as the best antiviral agent now available ... IF used at the proper dose. Vitamin C can neutralize and eliminate a wide range of toxins. Vitamin C will enhance host resistance, greatly augmenting the immune system's ability to neutralize bacterial and fungal infections. Now the National Institutes of Health has published evidence demonstrating vitamin C's anti-cancer properties. With so many medical benefits, why do so few doctors know of them? <br />
<br />
One explanation stems from ascorbic acid's designation as a "vitamin." Consider Dorland's Illustrated Medical Dictionary's definition of vitamin: A general term for a number of unrelated organic substances that occur in many foods in small amounts that are necessary in trace amounts for the normal metabolic functioning of the body. As a vitamin, only a minuscule 60 mg of ascorbic acid is needed to prevent the emergence of scurvy symptoms. As a medical treatment for cancer and life-threatening infections and toxic exposures, tens of thousands of milligrams of ascorbic acid must be administered, often by the intravenous (IV) as well as the oral route. <br />
<br />
The Center's founder, Dr. Hugh Riordan, was a true scientist who believed in the power of scientific measurement over dogma. With the establishment of The Center in 1975, he routinely checked plasma vitamin C levels in chronically ill patients. He found these sick patients to be consistently low in their plasma C levels. Interestingly enough, the cancer patients he was seeing had VERY LOW vitamin C reserves. This matched scientific literature documenting low vitamin C levels in cancer patients. Cancer cells were actively taking up vitamin C in a way that depleted tissue reserves of C. <br />
<br />
PET scans are commonly ordered by oncologists to evaluate their cancer patients for metastases (cancer spread to other organs). What is actually injected into the patient at the start of the scan is radioactive glucose. Cancer cells are anaerobic obligates, which means they depend upon glucose as their primary source of metabolic fuel. Cancer cells employ transport mechanisms called glucose transporters to actively pull in glucose. <br />
<br />
In the vast majority of animals, vitamin C is synthesized from glucose in only four metabolic steps. Hence, the molecular shape of vitamin C is remarkably similar to glucose. (Figure 1) Cancer cells will actively transport vitamin C into themselves, possibly because they mistake it for glucose. Another plausible explanation is that they are using the vitamin C as an antioxidant. Regardless, the vitamin C accumulates in cancer cells.<br />
<br />
Figure 1<br />
<br />
If large amounts of vitamin C are presented to cancer cells, large amounts will be absorbed. In these unusually large concentrations, the antioxidant vitamin C will start behaving as a pro-oxidant as it interacts with intracellular copper and iron. This chemical interaction produces small amounts of hydrogen peroxide. <br />
<br />
Because cancer cells are relatively low in an intracellular anti-oxidant enzyme called catalase, the high dose vitamin C induction of peroxide will continue to build up until it eventually lyses the cancer cell from the inside out! This effectively makes high dose IVC a non-toxic chemotherapeutic agent that can be given in conjunction with conventional cancer treatments. Based on the work of several vitamin C pioneers before him, Dr. Riordan was able to prove that vitamin C was selectively toxic to cancer cells if given intravenously. This research was recently reproduced and published by Dr. Mark Levine at the National Institutes of Health. <br />
<br />
As feared by many oncologists, small doses may actually help the cancer cells because small amounts of vitamin C may help the cancer cells arm themselves against the free-radical induced damage caused by chemotherapy and radiation. Only markedly higher doses of vitamin C will selectively build up as peroxide in the cancer cells to the point of acting in a manner similar to chemotherapy. These tumor-toxic dosages can only be obtained by intravenous administration. <br />
<br />
Over a span of 15 years of vitamin C research, Dr. Riordan's RECNAC (cancer spelled backwards) research team generated 20 published papers on vitamin C and cancer. RECNAC even inspired its second cancer research institute, known as RECNAC II, at the University of Puerto Rico. This group recently published an excellent paper in Integrative Cancer Therapies, titled "Orthomolecular Oncology Review: Ascorbic Acid and Cancer 25 Years Later." RECNAC data has shown that vitamin C is toxic to tumor cells without sacrificing the performance of chemotherapy. <br />
<br />
Intravenous vitamin C also does more than just kill cancer cells. It boosts immunity. It can stimulate collagen formation to help the body wall off the tumor. It inhibits hyaluronidase, an enzyme that tumors use to metastasize and invade other organs throughout the body. It induces apoptosis to help program cancer cells into dying early. It corrects the almost universal scurvy in cancer patients. Cancer patients are tired, listless, bruise easily, and have a poor appetite. They don't sleep well and have a low threshold for pain. This adds up to a very classic picture of scurvy that generally goes unrecognized by their conventional physicians. <br />
<br />
When Center cancer patients receive IVC, they report that their pain level goes down, and that they are better able to tolerate their chemotherapy. They bounce back quicker since the IVC reduces the toxicity of the chemotherapy and radiation without compromising their cancer cell killing effects. IVC is complementary to oncologic care. IVC is not "either/or" - it's a good "both/and" proposition. IVC can help cancer patients withstand the effects of their traditional therapies, heal faster, be more resilient to infection, develop a better appetite, and remain more active overall. These things promote a better response to their cancer therapy. <br />
<br />
IVC has been used for three decades here at The Center. There have been no serious complications, but there are a couple of potential complications that need to be screened for. Because vitamin C enhances iron absorption, iron overload must be ruled out. The high sodium load of IVC can create a fluid overload in a patient with congestive heart failure, renal insufficiency or failure. We also check our patients for G6PD deficiency (an enzyme used to maintain stability of the red blood cell membranes). Although many physicians worry that large doses of vitamin C may cause kidney stones, we have rarely seen the phenomenon, and several huge clinical trials in the medical literature refute this misconception. <br />
<br />
To summarize, most organisms make their own vitamin C. When they are under stress, either by illness or injury, Mother Nature has provided them with a means to facilitate healing: they synthesize more ascorbic acid. As a result, they are in less pain, they remain active, they can sleep, and they have a better appetite: all functions which promote healing.<br />
<br />
Dr. Riordan once said that here at The Center, we don't treat cancer... we treat people who happen to have cancer. IVC is a tool that allows our Center physicians to harness a healing mechanism that our human ancestors lost long ago: the ability to dramatically increase tissue levels of vitamin C. Research shows that the astonishingly high levels achievable only by IVC not only help fight the risk of infection and the pain of metastases, they actually aid in the defeat of the cancer cells themselves, through a very elegant mechanism that does no harm to healthy cells. It's a discovery that the medical world is only beginning to discover. <br />
<br />
<i>Source: <a href="http://www.riordanclinic.org/who-we-are/team/hunninghake/">Ron Hunninghake, M.D.,<br />
</a>Chief Medical Officer, Olive W. Garvey Center for Healing Arts </i>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-47225754715537300222012-03-22T11:45:00.001-07:002012-03-22T12:17:25.089-07:00The Hippocratic Oath<center><table style="width: 400px;"><tbody>
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Perhaps the most enduring - certainly the most quoted - tradition in the history of medicine is the Hippocratic Oath. Named after the famous Greek physician Hippocrates, this oath was written as a guideline for the medical ethics of doctors. Although the exact words have changed over time, the general content is the same - an oath to respect those who have imparted their knowledge upon the science of medicine, and respect to the patients as well as the promise to treat them to the best of the physicians' ability.<br />
<br />
</td><td></td><td><img src="http://www.annybelle.org/HippocraticOath.jpg" width="200" /></td></tr>
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<span style="font-size: large;"><b>Original, translated into English: </b></span><br />
<br />
I swear by Apollo, the healer, Asclepius, Hygieia, and Panacea, and I take to witness all the gods, all the goddesses, to keep according to my ability and my judgment, the following Oath and agreement:<br />
<br />
To consider dear to me, as my parents, him who taught me this art; to live in common with him and, if necessary, to share my goods with him; To look upon his children as my own brothers, to teach them this art; and that by my teaching, I will impart a knowledge of this art to my own sons, and to my teacher's sons, and to disciples bound by an indenture and oath according to the medical laws, and no others.<br />
<br />
I will prescribe regimens for the good of my patients according to my ability and my judgment and never do harm to anyone.<br />
<br />
I will give no deadly medicine to any one if asked, nor suggest any such counsel; and similarly I will not give a woman a pessary to cause an abortion.<br />
<br />
But I will preserve the purity of my life and my arts.<br />
<br />
I will not cut for stone, even for patients in whom the disease is manifest; I will leave this operation to be performed by practitioners, specialists in this art.<br />
<br />
In every house where I come I will enter only for the good of my patients, keeping myself far from all intentional ill-doing and all seduction and especially from the pleasures of love with women or with men, be they free or slaves.<br />
<br />
All that may come to my knowledge in the exercise of my profession or in daily commerce with men, which ought not to be spread abroad, I will keep secret and will never reveal.<br />
<br />
If I keep this oath faithfully, may I enjoy my life and practice my art, respected by all humanity and in all times; but if I swerve from it or violate it, may the reverse be my life.<br />
<br />
<span style="font-size: large;"><b>Classic translation into English:</b></span><br />
<br />
I swear by Apollo the Physician and Asclepius and Hygieia and Panaceia and all the gods, and goddesses, making them my witnesses, that I will fulfill according to my ability and judgment this oath and this covenant:<br />
<br />
To hold him who has taught me this art as equal to my parents and to live my life in partnership with him, and if he is in need of money to give him a share of mine, and to regard his offspring as equal to my brothers in male lineage and to teach them this art – if they desire to learn it – without fee and covenant; to give a share of precepts and oral instruction and all the other learning to my sons and to the sons of him who has instructed me and to pupils who have signed the covenant and have taken the oath according to medical law, but to no one else.<br />
<br />
I will apply dietic measures for the benefit of the sick according to my ability and judgment; I will keep them from harm and injustice.<br />
<br />
I will neither give a deadly drug to anybody if asked for it, nor will I make a suggestion to this effect. In purity and holiness I will guard my life and my art.<br />
<br />
I will not use the knife, not even on sufferers from stone, but will withdraw in favor of such men as are engaged in this work.<br />
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Whatever houses I may visit, I will come for the benefit of the sick, remaining free of all intentional injustice, of all mischief and in particular of sexual relations with both female and male persons, be they free or slaves.<br />
<br />
What I may see or hear in the course of treatment or even outside of the treatment in regard to the life of men, which on no account one must spread abroad, I will keep myself holding such things shameful to be spoken about.<br />
<br />
If I fulfill this oath and do not violate it, may it be granted to me to enjoy life and art, being honoured with fame among all men for all time to come; if I transgress it and swear falsely, may the opposite of all this be my lot.<br />
<br />
<span style="font-size: large;"><b>Modern version</b></span><br />
<br />
<i>A widely used modern version of the traditional oath was penned in 1964 by Dr. Louis Lasagna, former Principal of the Sackler School of Graduate Biomedical Sciences and Academic Dean of the School of Medicine at Tufts University:</i><br />
<br />
I swear to fulfill, to the best of my ability and judgment, this covenant:<br />
<br />
I will respect the hard-won scientific gains of those physicians in whose steps I walk, and gladly share such knowledge as is mine with those who are to follow.<br />
<br />
I will apply, for the benefit of the sick, all measures [that] are required, avoiding those twin traps of overtreatment and therapeutic nihilism.<br />
<br />
I will remember that there is art to medicine as well as science, and that warmth, sympathy, and understanding may outweigh the surgeon's knife or the chemist's drug.<br />
<br />
I will not be ashamed to say "I know not", nor will I fail to call in my colleagues when the skills of another are needed for a patient's recovery.<br />
<br />
I will respect the privacy of my patients, for their problems are not disclosed to me that the world may know. Most especially must I tread with care in matters of life and death. If it is given to me to save a life, all thanks. But it may also be within my power to take a life; this awesome responsibility must be faced with great humbleness and awareness of my own frailty. Above all, I must not play at God.<br />
<br />
I will remember that I do not treat a fever chart, a cancerous growth, but a sick human being, whose illness may affect the person's family and economic stability. My responsibility includes these related problems, if I am to care adequately for the sick.<br />
<br />
I will prevent disease whenever I can, for prevention is preferable to cure.<br />
<br />
I will remember that I remain a member of society with special obligations to all my fellow human beings, those sound of mind and body as well as the infirm.<br />
<br />
If I do not violate this oath, may I enjoy life and art, be respected while I live and remembered with affection thereafter. May I always act so as to preserve the finest traditions of my calling and may I long experience the joy of healing those who seek my help.<br />
<br />
<span style="font-size: x-small;">Source: <a href="http://en.wikipedia.org/wiki/Hippocratic_Oath">http://en.wikipedia.org/wiki/Hippocratic_Oath</a></span>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-69905269176563712672012-03-22T01:14:00.001-07:002012-03-22T01:26:43.987-07:00GET SMART ABOUT CANCER<span style="font-family: Georgia, "Times New Roman", serif;">When you first walk into the oncologist's office after your cancer diagnosis, you need to be smarter than he or she is about cancer. What? Smarter than the cancer specialist? Yes. Exactly. If you want to survive your cancer and get your cancer under control, you need to be smarter than your oncologist.</span><br />
<span style="font-family: Georgia, "Times New Roman", serif;"><br />
</span><br />
<span style="font-family: Georgia, "Times New Roman", serif;">Why?</span><br />
<span style="font-family: Georgia, "Times New Roman", serif;"><br />
</span><br />
<span style="font-family: Georgia, "Times New Roman", serif;">THE CANCER "SYSTEM"</span><br />
<span style="font-family: Georgia, "Times New Roman", serif;"><br />
</span><br />
<span style="font-family: Georgia, "Times New Roman", serif;">All conventional cancer treatment today is driven and controlled by drug company money and investment in "equipment." Any competition is brutally suppressed, with the cooperation of our Federal and State governments. Many books have been written on this subject, some better than others. One especially good one is "Politics in Healing," by Daniel Haley. The fact of the corruption is very real. Don't you be a victim of it. </span><br />
<br />
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<br />
A FEW FACTS<br />
<br />
<br />
* Since the 1930's in the U.S. alone, over 350 treatments for cancer which are gentle and non-toxic have healed cancer patients. Some treatments have healed hundreds. Many have healed thousands. I know many of the people who have been healed by them. Why won't you hear about these from your cancer doctor? Because they are all natural substances. Therefore, they cannot be patented and offer no profit to the pharmaceutical companies. This simple fact drives all conventional cancer treatments.<br />
<br />
* Since 1971, when President Nixon declared "War on Cancer," cancer deaths per 100,000 population have risen steadily. If you were the General in charge of this "war," you almost certainly would have scrapped your strategy for something different by now. Instead we, the taxpayers, keep funding the National Cancer Institute (NCI). This year their budget request is for $6.2 billion (with a "b") of your tax money. This agency was established in 1937. Not once in their 72-year history have they honestly tested even one of the 350 "alternative" substances mentioned above.<br />
<br />
* 55% of Food and Drug Administration (FDA) executives are employed by a pharmaceutical company when they leave the FDA. Several ex-Congressmen are among the 1,214 full-time lobbyists for "Big Pharma" in Washington. The pharmaceutical companies are the largest contributors to political campaigns.<br />
<br />
* The average cancer patient generates $1,300,000 of revenue for the cancer treatment "system" before they die. This is invisible to most cancer patients because much of it is covered by private insurance or Medicare/Medicaid. Over 1.2 million Americans are diagnosed with cancer each year. Over 570,000 Americans die of their cancer every year -- 1,500 every day. Cancer treatment is REALLY big business.<br />
<br />
* According to Forbes magazine, AstraZeneca made $630 million in 2001 on one breast cancer drug. Thay call it Nolvadex (commonly known as Tamoxifen). Why has the name been changed? Because the original patent for this drug was issued in 1972. It has been extended, as is typical for expensive prescription drugs, by manipulation of the filler and packaging and other trivial changes made by AstraZeneca to extend the life of the patent and avoid cheaper generic forms of this drug.<br />
<br />
* Have you ever wondered why a drug company would spend $200-500 million testing a new drug? Tamoxifen aka Nolvadex alone has made AstraZeneca and its predecessor companies over $23 billion in the last 39 years. Forbes estimated that AstraZeneca would make $2.6 billion in 2002 on cancer drugs alone.<br />
<br />
* Because of politics, our government's Medicare system encourages the fraud and abuse that is rampant among oncologists. For example, the chemotherapy drug Etoposide is sold wholesale to oncologists for them to administer it to cancer patients in their office. The cost to the oncologist is $7.50 for a 100mg dose. The allowable Medicare reimbursement, however, is $129.24 for that same 100mg dose. The consumer (you and I) pay a co-payment of $25.87 for this dose -- almost three and a half times the doctor's cost! Medicare pays the rest from our tax dollars.<br />
<br />
* According to the Journal of the American Medical Association (JAMA), the average oncologist makes $253,000 a year. Of this, 75% is profit on chemotherapy drugs administered in his or her office. All of these drugs, like Tamoxifen and Etoposide, treat the symptoms of cancer, not its causes, and make the patient's condition worse.<br />
<br />
* A recent survey of the 64 oncologists on the staff at McGill Cancer Therapy Center in Montreal found that 58 of them (91%) said they would not take chemotherapy or allow their family members to take it for cancer treatment. Why not? Too toxic and not effective. Today, 75% of cancer patients are administered chemotherapy. Go figure!<br />
<br />
* Very few oncologists advise their patients that there are dozens of substances available which are inexpensive and effectively offset the side effects of chemotherapy and radiation. Why? They just don't know about them. They're too busy to study what my readers and I study -- or too close-minded -- or both.<br />
<br />
* The long-term survival rate of cancer patients with metastasized cancer treated with chemotherapy is 3%. Most of the "alternative" substances I discuss have long-term survival rates of 50-70% when used alone (few of them are used alone). Combinations of different and compatible "alternative" substances boost survival rates to 90% or more.<br />
<br />
* A recent survey by Life Extension Foundation found that 80% of cancer patients take some "alternative" substances for their cancer. Half of them do not tell their cancer doctor what they are taking. Obviously, this is a sad testimony to the "ignorance and arrogance" of the cancer treatment "system."<br />
<br />
Enough? Do you see why you must be aware of the cancer treatment environment before you "submit" to treatment? Our medical system has been completely corrupted by drug company money. You and I are not going to be able to change this in our lifetimes. What we can do, and what I'm dedicated to helping you do, is survive chronic, degenerative diseases like cancer by being aware of this and taking charge of our own health care. <br />
<span style="font-size: x-small;">Source: </span>Bill Henderson - Cancer Free<span style="font-size: x-small;"> </span><br><a href="http://www.diseasefreezone.com/" target="_blank"><span style="font-size: x-small;">http://www.diseasefreezone.com/</span></a><br><br>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-34059448406215889442012-03-04T18:57:00.000-08:002012-03-04T18:57:00.330-08:00Louis Pasteur vs. Antoine BechampMainstream medicine believes that virtually all illness is caused by germs or genetic hereditary weakness, as well as deformities and trauma injuries. Their solution and strategy is to have us believe that there are over 10,000 different diseases and that each of these diseases requires outside intervention from drugs and surgery. The truth is that most illness is due to cellular malfunction caused by cellular toxicities and cellular malnutrition, both of which can be avoided and overcome naturally.<br />
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It was Louis Pasteur, the so-called "father of modern germ theory" so widely revered by mainstream medicine, who was largely responsible for germ theory being a primary precept of today`s medical practice. Few people are aware of the controversy which surrounded Pasteur in his early days or of the work of a more esteemed contemporary whose works Pasteur plagiarized and distorted. That contemporary was fellow French Academy of Sciences member Antoine Bechamp, one of France`s most prominent and active researchers and biologists whose theories and research results stood in stark opposition to Pasteur`s germ theory.<br />
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Pasteur essentially dug up the germ theory of disease and put his name on it. It wasn`t a new idea. The concept, which theorizes that many diseases are caused by germs, had actually been outlined by other people many years before. Pasteur nevertheless claimed to have "discovered" germs. Bechamp, on the other hand, proved through original research that most diseases are the result of diseased tissue and that bacteria and viruses are largely after-effects instead of causes of disease.<br />
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Antoine Bechamp was able to scientifically prove that germs are the chemical by-products and constituents of pleomorphic microorganisms enacting upon the unbalanced, malfunctioning cell metabolism and dead tissue that actually produces disease. Bechamp found that the diseased, acidic, low-oxygen cellular environment is created by a toxic/nutrient deficient diet, toxic emotions, and a toxic lifestyle. His findings demonstrate how cancer develops through the morbid changes of germs to bacteria, bacteria to viruses, viruses to fungal forms and fungal forms to cancer cells.<br />
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After some initial controversy, Pasteur`s germ theory ended up winning the day with mainstream medicine - owing in large part to the fact that the theory enabled mainstream medicine to hugely profit from the patented drugs and treatments for fighting germs. After all, had Bechamp`s discoveries been incorporated into current medical curriculum, it would likely have meant a virtual elimination of disease and the end of the pharmaceutical industry.<br />
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The germ theory of medicine stands in stark contrast to thousands of years of man looking to nature to nourish and heal it, dating back to ancient Chinese medicine which treated the whole body instead of the symptoms of illness. As Hippocrates, "the father of medicine" observed 2400 years ago, "Nature is the physician of man." Hippocrates also advised, "Leave your drugs in the chemist`s pots if you can cure your patient with food."<br />
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Though mainstream medicine might have us believe otherwise, the simple truth is that no one ever became ill due to a deficiency in pharmaceutical drugs. Lack of nutrition combined with exposure to toxins is what causes us to become ill.<br />
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Someday, germ theory and unnatural drugs will be relegated to the science junk pile where they belong and man will re-discover the value of eating a nutrient-dense organic diet, avoiding toxins and nutritional deficiencies and living a healthy lifestyle. When that happens, the words of Thomas Edison may prove to be a welcome prophesy:<br />
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"The doctor of the future will give no medicine but will interest his patients in the care of the human frame, in diet and in the cause and prevention of disease."<br />
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Source: <a href="http://theashbulletin.blogspot.com/2012/03/louis-pasteur-vs-antoine-bechamp.html">http://theashbulletin.blogspot.com/2012/03/louis-pasteur-vs-antoine-bechamp.html</a>Unknownnoreply@blogger.com3tag:blogger.com,1999:blog-1517448691385361754.post-85575869072029349052010-09-02T17:07:00.001-07:002012-04-10T21:44:06.528-07:00The Law of Health and DiseaseJust as there is the Law of Gravity, Law of Relativity and Law of Attraction there is also the Law of Health and Disease.<br />
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Neglecting this simple Law of Health & Disease is the major contributor to the current health care crisis facing this nation and others around the world. The numbers being diagnosed with and treated for degenerative diseases continue to rise. Increase in the costs of treating these so-called diseases also continues to rise.<br />
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Unfortunately, the Law of Health and Disease is not taken under consideration nor is it being factored in to the diagnosis, prognosis, medical treatment plans or procedures provided by the medical mainstream professionals or the alternative health care community.<br />
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However, the Law of Health and Disease IS recognized and addressed in sound science. Sound science is 100%. The Advanced Scientific Health Group has developed an entire, concise and comprehensive education program for anyone willing to learn.<br />
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Science has proven that the human body was Created PERFECTLY. Applying the knowledge from the Insider Doctors and Scientists will be your proof.<br />
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Isn't it time we take a more logical approach to health and disease?<br />
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Live, Love & Breathe,<br />
<br />
Vickie Barker - ASH Family Advocate<br />
<a href="http://www.advancedscientifichealth.net/">http://www.advancedscientifichealth.net/</a>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-7616798770938473602010-01-24T14:46:00.001-08:002010-01-24T14:46:52.789-08:00Element III: Hormonal BalanceThe third element is the balance between the hormone insulin and growth hormone. People with the highest levels of the growth hormone somatotrophin (STH) live the longest.<br />
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Insulin, produced in the pancreas, is secreted to regulate the rate at which the body utilizes carbohydrates. When we consume carbohydrates (sugars and starches), insulin is released to lower the level of sugar (glucose) in the blood. Insulin also promotes the use of glucose as an energy source for the body, promotes the storage of fat and encourages the conversion of proteins to fat for storage.<br />
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Produced in the pituitary gland, STH increases the rate of protein synthesis, affects the metabolism of sodium, potassium and calcium and influences the metabolism of carbohydrates. The purpose of STH is to convert the body's available energy into bone, muscle and tissue growth.<br />
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When we are young, our bodies have a low ratio of insulin to STH so we are healthier, leaner, full of energy-and growing. The insulin encourages the body to store carbohydrates as fat while STH stimulates the burning of that fat.<br />
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Due to age and inactivity, stored carbohydrates accumulate in the form of fat. Because we are now full-grown, the hypothalamus tells the pituitary gland to release less and less STH. This causes the pancreas to produce more insulin in order to maintain proper blood sugar levels. The visible result of this hormonal imbalance is weight gain. The chronic symptoms of this imbalance is hypoglycemia. If not corrected, diabetes is the end result.<br />
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There are no surgeries that can be performed nor drugs that can be taken to maintain optimal levels of both insulin and STH.Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-79209346390818156032010-01-24T13:52:00.000-08:002010-01-24T13:52:05.630-08:00Element II: Acid/alkaline BalanceThe second element is the acid/alkaline balance in the body. It is monitored by measuring the "pH (the symbol for hydrogen ion concentration)" which is regulated by the body's oxygen saturation level. The body must be slightly alkaline for its cells to be properly oxygenated.<br />
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The pH scale goes from zero to 14-zero being purely acid, 14 being purely alkaline and 7 being "neutral pH."<br />
Without exception, people with cancer have a pH below 7.0, which means their tissues, their cells, are not being properly oxygenated. This condition is called "acidosis."<br />
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People with a body pH over 7.4 do not have cancer because their cells and tissues are being properly oxygenated.<br />
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Contrary to current medical information, cancer is the easiest of all degenerative diseases to understand and is readily reversible without dangerous drugs and surgeries.<br />
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The body is constantly regulating the replacement of worn out cells while creating new cells to repair tissue damage.<br />
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"Cancerous" is the term applied to cells that reproduce in an unregulated manner until they form a tissue mass, or "tumor."<br />
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In order to create a cancerous cell in the lab, technicians simply withhold oxygen from a healthy cell and it becomes cancerous within a few hours. Conversely, supplying the cancerous cell with more oxygen than was withheld from it causes that cancerous cell to die within a few hours.<br />
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An individual cell cannot be cured of cancer; once cancerous, the cell must be destroyed.<br />
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The natural way to accomplish the feat of destroying cancer cells is exposing them to oxygen. Increasing the amount of oxygen available to the cells is accomplished by elevating body pH through diet and exercise.<br />
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In cases where elevating body pH is critical, the most alkalinizing element known to man is cesium. Daily intake of cesium, with potassium, will quickly increase body pH. It has been demonstrated that cancerous cells cannot survive in a pH of 8.0.<br />
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Once cancerous cells have been destroyed, maintaining body pH at 7.4-7.5 will prevent cells from becoming cancerous.<br />
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There are no surgeries that can be performed nor drugs taken that will restore or maintain the body's acid/alkaline balanceUnknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-66449429094429537972010-01-24T13:46:00.000-08:002010-01-24T13:46:50.157-08:00Element I: The collagen matrixThe entire body is held together by connective tissue. Collagen is the strong, fibrous protein that serves as the building block for connective tissues-including skin, tendons, ligaments, eyes and arteries.<br />
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Collagen is like the glue that holds the body together. Collagen production is dependent upon ample supplies of ascorbates.<br />
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While most animals produce their own ascorbates from the food they eat, humans, guinea pigs, fruit bats and primates do not. Scientists believe that about 10,000 years ago humans could produce their own ascorbates.<br />
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Unless sufficient quantities of usable ascorbates are ingested daily, the collagen matrix becomes stiff and brittle: Skin wrinkles, backs ache, ligaments pull and the little sacs in the lungs get stiff-causing blood vessels and arteries to crack.<br />
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Also critical to the production of collagen are the amino acids lysine and proline. When our bodies do not have enough vitamin C, they cannot use the amino acids lysine and proline to make the proper cross links in the collagen. Like ascorbates, humans must obtain lysine from dietary sources. Our dietary intake is usually deficient in lysine. Proline can be produced by the body but usually in inadequate quantities. Lysine and proline are essential for proper collagen formation and to prevent cholesterol build-up in the form of plaque.<br />
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Symptoms caused by ascorbate deficiencies (and the body's subsequent inabilityto utilize lysine and proline) are traditionally referred to as "scurvy." The body can, for a time, manufacture enough lipoproteins from blood plasma to "patch" the vesicular/arterial cracks. The patch material is commonly called "plaque." As the plaque gets thicker, vessels and arteries can no longer flex and blood flow is restricted.<br />
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As a result, the resting heart rate increases. This condition is commonly diagnosed as "high blood pressure."<br />
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Over time, vessels and arteries can become so cracked and plaqued that people lose blood internally, eventually resulting in a heart attack.<br />
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High blood pressure, also known as hypoascorbemia, is advance warning that the host is preparing to become another heart disease statistic.<br />
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A diet rich in ascorbates can prevent scurvy and, to some extent, therapeutic doses of ascorbic acid (vitamin C) can reverse the deficiency and other chronic conditions created by a lack of vitamin C. But ascorbic acid is only one form of ascorbate and can cause digestive discomfort when therapeutic doses are administered.<br />
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Buffered mineral ascorbates (sodium ascorbate, calcium ascorbate and potassium ascorbate) can be taken daily in larger quantities without discomfort. The only substances capable of healing damaged vessels and arteries are ascorbates.<br />
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It should also be noted that the presence of buffered mineral ascorbates prevents and/or reverses the symptoms of high blood sugar, commonly referred to as "diabetes."<br />
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There are no surgical procedures to be performed nor drugs taken that will remove the plaque and heal cracked vessels and arteries.Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-48809835402715646282010-01-24T13:21:00.000-08:002010-01-24T13:21:49.646-08:00Three Elements of Optimal HealthOur health relies on trillions of cells repeatedly performing billions of specialized functions. Though the processes and systems that animate our bodies are phenomenally complex, what the cells driving them need is simple-simple to understand and simple to provide. You are about to discover the three elements of optimal health-the collagen matrix, acid/alkaline balance and hormonal balance.<br />
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It is a well-established fact that the surest and safest defenses of the body against germs and diseases are normal blood and digestive juices and that a diminution in this bactericidal power means a 'run-down' condition of the person. It is an equally well established fact that the only sure and lasting defenses of the body against a run-down condition are good nutrition, hygiene, work and personal habits. A healthy body is self-immune. Devoting some study to the analysis and understanding of the body's means at self-immunization is fruitful of rewards. Much is known in the literature on this subject but little has been made practical. Physiologists know that normal blood and digestive juices possess chemical substances that are inimical to the life of our bacterial foes. If we can analyze the chemical changes in the blood and tissues which cause a person to get 'run down' and put him at the mercy of his bacterial foes, we surely can work out a normal beneficent method of increasing the blood's store of normal bactericidal substances. In living we produce body-acids and by eating we supply food-alkali. We are built up by foods that are made up of acid-forming and base-forming elements, and our metabolism is such that our blood is, so to speak, always on the verge of turning acid.<br />
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We are saved from that evil by the alkali in the blood and tissues which, of course, derive them from our foods. The body is a factory in which occurs an incessant mating and unmating of acid and alkaline substances. It is capable of health and survival only to the extent of understanding and heeding the mating and unmating of acid-forming and base-forming substances of the blood with the acid-forming and base-forming substances of foods. Normal alkalinity of the blood and tissues must be maintained through the foods, or disease appears. If the body is lacking in alkali it necessarily with holds from neutralization and elimination a certain amount of poisonous organic and mineral acids. We breathe air into the lungs to rob it of oxygen which is taken up by the arterial blood and carried to the tissues where the carbon is burned or oxidized. This burning of carbon yields carbonic acid, which then is returned by the venous blood to the lungs to be breathed out. The balance of the carbonic acid yielded by tissue-oxidation is neutralized in the tissues and eliminated mostly through the kidneys. The inevitable result of a retention of carbonic acid and its compounds beyond the normal quotient in the blood and tissues brings on that 'run down' which invites and underlies bacterial and other diseases. Carbonic acid and its compounds deplete the blood and tissues of their supply of alkali, and thus produce the abnormal changes which develop disease. This alkali-depleting activity is characteristic of all organic and mineral acids produced in the body. The blood and tissues are supplied through the foods with 'free' and 'fixed' bases or alkali. During the formative stage of any disease the first alkali to go are the free, and the last to go are the fixed, All tissues or organs do not yield their fixed alkali with the same ease.<br />
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The digestive cells, or the liver cells, or the brain cells may be the first to answer the blood's call for more alkali in some cases, whereas in others the kidneys or the lungs will be the first to give up their reserve of fixed alkali in order to control or check the disease. So there are really no fundamental differences between diseases. The difference is merely in the particular functional importance of the special organ or tissue subjected by the blood to the greatest drain of alkali. During the prodromal stage, say of pneumonia, there occurs an impoverishment of the patient's blood in alkali; then follows an impoverishment of the tissue-alkali more or less generally, but localizing itself more specifically in the lungs. This dilucidation of the etiology and modus operandi of diseases is accurate. It has the support of science and gives a well-defined significance to the cause and course of specific diseases. This interpretation also suggests the normal means for conferring immunity as well as for aborting and curing diseases through the alkali-bearing foods. The underlying cause of infectious diseases is, therefore, an alkali-depleted diet, and the underlying cause for failure to abort and cure infectious diseases in an alkali-depleted dietetic treatment. The evidence that this is correct is overwhelming. It has long been known that protein bases are essential components of the activated defense-yielding substances of foods, called vitamines. Foods are said to be 'nutritious' and 'non-nutritious,' according as they yield much or little nitrogenous, carbohydrate and fat substances. In keeping with this conception, foods were long ago divided into (1) Proteins, (2) Carbohydrates, (3) Fats. Fruits and green vegetables are not classified. The wonderful vitalizing acids and salts they yield are relegated to the "ash" column. Nevertheless, fruits and green vegetables yield to the blood more activating acids and bases than all nutritious foods together, and, moreover, yield them with little or no demand on digestion, absorption and assimilation. These particular acids and bases readily travel to the blood and are quickly utilized to build up and repair tissues, to promote immunity to and recovery from diseases.<br />
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All treatments must prove unsatisfactory or failures if (1) the oxygen-intake and (2) the alkali- yield are deficient.<br />
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Source: <a href="http://www.advancedhealthplan.com/autopathy.html">Advanced Health Plan - Autology</a>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-38721600326081730782010-01-24T11:57:00.000-08:002010-01-24T11:57:01.823-08:00Reversing Chronic DiseaseMost people believe that genetics or bad luck gave them diseases for which the only treatments are drugs and surgeries. As a result, organized medicine will sell an estimated two-trillion-dollars worth of drugs and surgeries in 2005.<br />
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Drugs and surgeries are obviously not the solution to our medical problems; each year more, not fewer people die slowly (and expensively) from pharmaceutically and surgically-treated diseases.<br />
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Drs. Otto Warburg and Linus Pauling were awarded Nobel Prizes for pioneering simple, inexpensive protocols to prevent or reverse chronic illnesses such as cancer and heart disease. They determined that chronic diseases develop in the presence of acidic/unoxygenated cells caused by bodily imbalances resulting from malnutrition. Simply giving the body the few nutrients it needs restores balance; oxygenation and alkalinization then follow so that real healing can begin.<br />
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The process is truly elemental. By learning how your body works and why it gets sick, you can then obtain the non-patentable vitamins, minerals, enzymes and amino acids known to reverse disease symptoms that may have otherwise been terminal.<br />
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Once you know how your body works, you can teach others how their bodies work. Whether they know it yet or not, they are depending on you.<br />
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People can now arm themselves for the future with the knowledge from the past.<br />
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<a href="http://www.advancedscientifichealth.com/ashReversingChronicDiseaseIsElemental.asp?sid=798514">Advanced Scientific Health Research</a>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-74088019526811021952009-12-26T16:02:00.001-08:002012-03-04T18:43:57.076-08:00Great News! Project CompleteAdvanced Scientific Health (ASH), now has a new live online presence and an enhanced education and access program for Licensed Medical Practioners, Health Care Providers and Families. Through a coordinated effort a team of independent researchers have tried, tested and approved the protocols as set forth by the scientific community and as validated through the works of Nobel Laureates.<br />
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The facts and findings have been confirmed and the evidence<b> </b>supports the scientists' and doctors' contention that disease is a result of the progressive degeneration of the body's own natural ability to heal, protect and maintain its own health at optimum levels.<b> </b><br />
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Through general study and analysis as to why the information available through the scientific health community had not been made readily available to the medical health institutes and universities became quite apparent. <br />
Although many of the discoveries were reported and published to the professional medical journals such as J.A.M.A. etc these were never highly promoted through university and curriculum study. There has been no vehicle in place to promote or provide the findings to the public.<br />
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As the health care crisis increses in severety here in the United States, we see the need for a call to action. The ASH program is a solution for millions that are suffering. The program invites Medical professionals, health care workers and families to review the material. A website has been developed to provide audios, lectures and resources available via the internet to help medical professionals determine what level of participation would best serve their patients and how to best integrate the ASH program into their current service model.<br />
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A portion of the facts and findings will be posted here on the Scientific Health Journal to help anyone further their understanding in how to best help themselves and others in applying this life saving knowledge.<br />
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No one need suffer with pain and early death. The answers are here for anyone. A great place to start is to go back and review what worked before. A very easy to read publication is available free:<br />
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<a href="http://www.annybelle.org/Klenner_KEY_order_page.html">"Conclusions of Dr. Frederick Klenner M.D." </a><br />
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We will be releasing the findings here as we also roll out the program so please be patient. Should you have any questions, please feel free to contact us at: <a href="http://www.advancedhealthplan.com/ash_contactus.html" target="_blank">www.AdvancedScientificHealth.net</a> Welcome 2010 ~ We Are Ready !Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-78293015671547151812007-11-12T09:53:00.000-08:002010-01-01T08:14:34.760-08:00Ask INSIDER DoctorsInsider Doctors and Scientists have been able to restore their health and now anyone can do it.<br />
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The information provided from the Scientific Health Community is the key to helping any human body restore its basic abilities to heal itself.<br />
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Learning and applying the knowledge from the scientific community is helping thousands learn how their body's work at the cellular level. This is important, because this is where healing begins.<br />
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For too long this information was available only to a few, but by applying the knowledge we can all begin to experience a healing process.<br />
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Is is simple, safe and effective. It also is affordable.What you can learn from the <a href="http://www.annybelle.org/better_health_today.html">Ask Insider Doctors & Scientists for Better Health Today</a>e-book will now provide you the basic knowledge to help your cells overcome the deficiencies in basic nutrients they were intended to have.<br />
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The 3 basics that must be addressed for a healthy body are:<br />
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1) The Collagen Matrix<br />
2) The pH Balance<br />
3) The Hormonal Balance<br />
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Learn today by <a href="http://www.advancedscientifichealth.com/ashTheThreeElementsOfOptimalHealth.asp?sid=798514">CLICKING HERE</a> <br />
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For more information please join us on our Live Lecture calls each:<br />
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Saturday at 10:00am Pacific Time<br />
<b>1-212-990-8000 Pin# 3024</b><br />
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I do hope to hear you there. <i>You may also invite a guest should you know someone that may be suffering with any dis-ease.</i><br />
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We have many researchers that at one time were dealing with Cancer, Heart Disease, Multiple Sclerosis, Parkinson's, Diabetes, High Blood Pressure, High Cholestrol and many other degenerations. Come and visit with them, learn all you can. <br />
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Someone close to you is dying to hear about how they can begin to regain their health.<br />
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Blessings to you and yours,<br />
<br />
Vickie Barker<br />
<a href="http://www.advancedscientifichealth.com/ashTheThreeElementsOfOptimalHealth.asp?sid=798514">ASH researcher since 1999</a><br />
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"My people are destroyed for lack of knowledge" ~Hosea 4:6Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1517448691385361754.post-67597720635872343302007-09-21T13:58:00.000-07:002007-09-21T14:02:51.344-07:00Oprah Winfrey- Autism and Mercury Vaccination Connection<span style="font-size:85%;"><span style="font-family: Arial,Helvetica,sans-serif;"><b>The Autism Mercury Vaccine Connection</b><br /><br />There is more information available than ever before about autism and the link to mercury (thermisol) ingredients found in vaccinations. The important fact as well is that there are ways through diet and learning how to build the body back to what it was intended to have available through supplementation.<br /><br />There is an Independent Research Group that is now providing an education program based on their findings in the scientific health community. The scientific health community has never before had a vehicle to bring this information to health care providers and families.<br /><br />I recommend taking a serious look. Do it for you, do it for your children and do it for the generations to come. We must act for the good of all. There are several websites that will help you find some answers, alerts and people who do in fact care. The medical mainstream as we all know functions on the primary goal of increased revenue. Unfortunately this is at the expense of our loved ones.<br /><br /></span></span><a href="http://www.annybelle.org/" target="_blank">AnnyBelle.org</a><br /><br /><a href="http://www.advancedhealthplan.com/" target="_blank">Advanced Health Education Program</a><br /><br /><a href="http://www.advancedhealthplan.com/autisim_mercury_vaccination.html" target="_blank">Autism Mercury Connection with Oprah Winfrey and Robert Kennedy Jr.</a>Unknownnoreply@blogger.com1